TF Information

Zfp335 *(Mus musculus)* C2H2 ZF
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00096 (zf-C2H2)	IPR007087	ENSMUSG00000039834	T101157_2.00	Ensembl (2018-Dec-8)	Link out
NCBI Gene Info: Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in brain development and positive regulation of neuroblast proliferation. Acts upstream of or within several processes, including in utero embryonic development; nervous system development; and regulation of histone H3-K4 methylation. Located in nucleus. Part of histone methyltransferase complex. Is expressed in brain and future brain. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 10. Orthologous to human ZNF335 (zinc finger protein 335). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
Zfp335 M08998_2.00	Mus musculus	RGSTGYCYNNNSHDNTGCCTGH	DCAGGCANHDSNNNRGRCASCY	Misc Kulakovskiy et al.(2013) ZN335_MOUSE.H11MO.0.A	(Direct)	(Direct)
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
ZNF335 M08952_2.00	Homo sapiens	RGSTGYCYNNNSHDNTGCCTGH	DCAGGCANHDSNNNRGRCASCY	Misc Kulakovskiy et al.(2013) ZN335_HUMAN.H11MO.0.A	0.814	0.970
For this family, TFs with SR scores > 0.755* will likely have a similar motif*

Links
Other C2H2 ZF family TFs
Other *Mus musculus* TFs

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24 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action