CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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Gtf3a
(
Rattus norvegicus
)
C2H2 ZF
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00096 (zf-C2H2)
IPR007087
ENSRNOG00000050016
T109296_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq, Jul 2008]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
Gtf3a
M10364_2.00
Rattus norvegicus
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TFIIIA_02
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
Gtf3a
M10338_2.00
Mus musculus
Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TFIIIA_01
0.791
0.942
For this family, TFs with SR scores >
0.755
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSRNOP00000065623
C2H2 ZF
38
62
FICSFPDCSASYNKAWKLDAHLCKH
ENSRNOP00000065623
C2H2 ZF
68
92
FVCDYEGCGKAFIRDYHLSRHILIH
ENSRNOP00000065623
C2H2 ZF
98
123
FVCADNGCNQKFSTKSNLKKHIERKH
ENSRNOP00000065623
C2H2 ZF
130
154
YVCNFEGCKKAFKKHQQLRTHQCQH
ENSRNOP00000065623
C2H2 ZF
160
183
FRCTHEGCGKHFASPSRLKRHGKR
ENSRNOP00000065623
C2H2 ZF
187
211
YLCQKGCSFVGKTWTELLKHTREAH
ENSRNOP00000065623
C2H2 ZF
215
237
VTCTVCQKMFKRKDHLKQHMKTH
ENSRNOP00000065623
C2H2 ZF
244
269
YRCPREGCARTYTTVFNLQSHILSFH
ENSRNOP00000065623
C2H2 ZF
275
299
FVCEHAGCGKTFAMKQSLMRHSVVH
Links
Other
C2H2 ZF
family TFs
Other
Rattus norvegicus
TFs
3 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy