Gtf3a (Rattus norvegicus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSRNOG00000050016 T109296_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Gtf3a
M10364_2.00
Rattus norvegicus Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TFIIIA_02
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Gtf3a
M10338_2.00
Mus musculus Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TFIIIA_01
0.791 0.942
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSRNOP00000065623 C2H2 ZF 38 62
ENSRNOP00000065623 C2H2 ZF 68 92
ENSRNOP00000065623 C2H2 ZF 98 123
ENSRNOP00000065623 C2H2 ZF 130 154
ENSRNOP00000065623 C2H2 ZF 160 183
ENSRNOP00000065623 C2H2 ZF 187 211
ENSRNOP00000065623 C2H2 ZF 215 237
ENSRNOP00000065623 C2H2 ZF 244 269
ENSRNOP00000065623 C2H2 ZF 275 299

Links

Other C2H2 ZF family TFs
Other Rattus norvegicus TFs

Invalid Input OrderBy

3 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action