ces-1 (Caenorhabditis elegans)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 WBGene00000468 T131549_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of programmed cell death and negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in head ganglion and head neurons. Orthologous to human SCRT1 (scratch family transcriptional repressor 1) and SCRT2 (scratch family transcriptional repressor 2). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ces-1
M00608_2.00		 Caenorhabditis elegans
CCTGTTG
CAACAGG		 PBM
Narasimhan et al.(2015)
pTH9158		 (Direct) (Direct)
ces-1
M09518_2.00		 Caenorhabditis elegans
NWAATYNRATTW
WAATYNRATTWN		 Misc
Heinz et al.(2010)
cElegans-L1-CES1_modEncode		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.755 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00608_2.00 C2H2 ZF 51 73
M00608_2.00 C2H2 ZF 82 104
M00608_2.00 C2H2 ZF 108 130
M00608_2.00 C2H2 ZF 136 158
M00608_2.00 C2H2 ZF 164 185

DNA Binding Domains

Protein ID Domain From To Sequence
F43G9.11 C2H2 ZF 134 156
F43G9.11 C2H2 ZF 165 187
F43G9.11 C2H2 ZF 191 213
F43G9.11 C2H2 ZF 219 241
F43G9.11 C2H2 ZF 247 268

Links

Other C2H2 ZF family TFs
Other Caenorhabditis elegans TFs

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3 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action