CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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ces-1
(
Caenorhabditis elegans
)
C2H2 ZF
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00096 (zf-C2H2)
IPR007087
WBGene00000468
T131549_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of programmed cell death and negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in head ganglion and head neurons. Orthologous to human SCRT1 (scratch family transcriptional repressor 1) and SCRT2 (scratch family transcriptional repressor 2). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
ces-1
M00608_2.00
Caenorhabditis elegans
CCTGTTG
CAACAGG
PBM
Narasimhan et al.(2015)
pTH9158
(Direct)
(Direct)
ces-1
M09518_2.00
Caenorhabditis elegans
NWAATYNRATTW
WAATYNRATTWN
Misc
Heinz et al.(2010)
cElegans-L1-CES1_modEncode
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
For this family, TFs with SR scores >
0.755
will likely have a similar motif
Experimental Constructs
Motif ID
Domain
From
To
Sequence
M00608_2.00
C2H2 ZF
51
73
CVCDKCGKSYATTSNLSRHKQTH
M00608_2.00
C2H2 ZF
82
104
KQCPHCDRVYVSMPALSMHILTH
M00608_2.00
C2H2 ZF
108
130
HECNVCGKRFSRLWLLQGHLRSH
M00608_2.00
C2H2 ZF
136
158
FSCAHCGKSFADRSNLRAHMLTH
M00608_2.00
C2H2 ZF
164
185
FECDKCGRRFALRAYLNRHLET
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
F43G9.11
C2H2 ZF
134
156
CVCDKCGKSYATTSNLSRHKQTH
F43G9.11
C2H2 ZF
165
187
KQCPHCDRVYVSMPALSMHILTH
F43G9.11
C2H2 ZF
191
213
HECNVCGKRFSRLWLLQGHLRSH
F43G9.11
C2H2 ZF
219
241
FSCAHCGKSFADRSNLRAHMLTH
F43G9.11
C2H2 ZF
247
268
FECDKCGRRFALRAYLNRHLET
Links
Other
C2H2 ZF
family TFs
Other
Caenorhabditis elegans
TFs
3 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy