CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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bcl-11
(
Caenorhabditis elegans
)
C2H2 ZF
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00096 (zf-C2H2)
IPR007087
WBGene00017430
T131625_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is expressed in head; hypodermis; muscle cell; neurons; and pharynx. Human ortholog(s) of this gene implicated in autism spectrum disorder; beta thalassemia; immunodeficiency 49; schizophrenia; and sickle cell anemia. Orthologous to human BCL11A (BAF chromatin remodeling complex subunit BCL11A) and BCL11B (BAF chromatin remodeling complex subunit BCL11B). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
bcl-11
M00641_2.00
Caenorhabditis elegans
NNTGACCRNN
NNYGGTCANN
PBM
Narasimhan et al.(2015)
pTH10807
(Direct)
(Direct)
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
For this family, TFs with SR scores >
0.755
will likely have a similar motif
Experimental Constructs
Motif ID
Domain
From
To
Sequence
M00641_2.00
C2H2 ZF
51
72
RCNFCNKVFTNRSNLIVHLRSH
M00641_2.00
C2H2 ZF
78
100
YKCQLCPYACAQSSKLTRHMRTH
M00641_2.00
C2H2 ZF
108
129
YHCYICRMPFSVHSTLEKHMRK
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
F13H6.1a
C2H2 ZF
495
516
RCNFCNKVFTNRSNLIVHLRSH
F13H6.1a
C2H2 ZF
522
544
YKCQLCPYACAQSSKLTRHMRTH
F13H6.1a
C2H2 ZF
552
573
YHCYICRMPFSVHSTLEKHMRK
F13H6.1b.1
C2H2 ZF
499
520
RCNFCNKVFTNRSNLIVHLRSH
F13H6.1b.1
C2H2 ZF
526
548
YKCQLCPYACAQSSKLTRHMRTH
F13H6.1b.1
C2H2 ZF
556
577
YHCYICRMPFSVHSTLEKHMRK
F13H6.1b.2
C2H2 ZF
499
520
RCNFCNKVFTNRSNLIVHLRSH
F13H6.1b.2
C2H2 ZF
526
548
YKCQLCPYACAQSSKLTRHMRTH
F13H6.1b.2
C2H2 ZF
556
577
YHCYICRMPFSVHSTLEKHMRK
Links
Other
C2H2 ZF
family TFs
Other
Caenorhabditis elegans
TFs
50 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy