daf-16 (Caenorhabditis elegans)
Forkhead

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00250 (Forkhead) IPR001766 WBGene00000912 T188799_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables several functions, including 14-3-3 protein binding activity; beta-catenin binding activity; and enzyme binding activity. Involved in several processes, including defense response to other organism; regulation of dauer larval development; and regulation of transcription, DNA-templated. Located in cytosol and nucleus. Is expressed in several structures, including germ line; gonad; hypodermis; neurons; and somatic cell. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in alveolar rhabdomyosarcoma. Orthologous to several human genes including FOXO1 (forkhead box O1); FOXO3 (forkhead box O3); and FOXO4 (forkhead box O4). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
daf-16
M01989_2.00		 Caenorhabditis elegans
NNRWMAAYAN
NTRTTKWYNN		 PBM
Weirauch et al.(2014)
pTH8995		 (Direct) (Direct)
daf-16
M10574_2.00		 Caenorhabditis elegans
RNHGTAAACAANHN
NDNTTGTTTACDNY		 Transfac
Matys et al.(2006)
N$DAF16_01		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Foxo4
M00794_2.00 		Mus musculus
NNRWMAAYAN
NTRTTKWYNN		 PBM
Weirauch et al.(2013)
pTH3731 		0.779 0.711
Foxo4
M09107_2.00 		Mus musculus
MVWAAACAA
TTGTTTWBK		 Misc
Kulakovskiy et al.(2013)
FOXO4_MOUSE.H11MO.0.C 		0.779 0.711
Foxo3
M00797_2.00 		Mus musculus
RTMAACAN
NTGTTKAY		 PBM
Weirauch et al.(2013)
pTH3749 		0.759 0.759
FOXO3
M03019_2.00 		Homo sapiens
GTAAACATGTTTAC
GTAAACATGTTTAC		 SELEX
Jolma et al.(2013)
FOXO3_1 		0.759 0.759
FOXO3
M03020_2.00 		Homo sapiens
GTAAACAW
WTGTTTAC		 SELEX
Jolma et al.(2013)
FOXO3_2 		0.759 0.759
FOXO3
M03021_2.00 		Homo sapiens
KTTCCCCACAC
GTGTGGGGAAM		 SELEX
Jolma et al.(2013)
FOXO3_3 		0.759 0.759
FOXO3
M04813_2.00 		Homo sapiens
HHCCCCACACN
NGTGTGGGGDD		 SELEX
Yin et al.(2017)
FOXO3_eDBD_HT-SELEX 		0.759 0.759
FOXO3
M09087_2.00 		Homo sapiens
DGTAAACAVV
BBTGTTTACH		 Misc
Kulakovskiy et al.(2013)
FOXO3_HUMAN.H11MO.0.B 		0.759 0.759
Foxo3
M09110_2.00 		Mus musculus
DGTAAACAVV
BBTGTTTACH		 Misc
Kulakovskiy et al.(2013)
FOXO3_MOUSE.H11MO.0.B 		0.759 0.759
FOXO3
M10537_2.00 		Homo sapiens
WAHGTAAACAAVND
HNBTTGTTTACDWW		 Transfac
Matys et al.(2006)
V$FOXO3_01 		0.759 0.759
FOXO3
M10538_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$FOXO3A_Q1 		0.759 0.759
FOXO3
M10539_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$FOXO3A_Q3 		0.759 0.759
FOXO3
M04814_2.00 		Homo sapiens
NHCCCCACACV
BGTGTGGGGDN		 SELEX
Yin et al.(2017)
FOXO3_eDBD_Methyl-HT-SELEX 		0.759 0.759
Foxo6
M00798_2.00 		Mus musculus
NNNNHHRYDN
NHRYDDNNNN		 PBM
Weirauch et al.(2013)
pTH3477 		0.755 0.687
FOXO6
M03049_2.00 		Homo sapiens
GTAAACATGTTTAC
GTAAACATGTTTAC		 SELEX
Jolma et al.(2013)
FOXO6_1 		0.755 0.687
FOXO6
M03050_2.00 		Homo sapiens
GTAAACA
TGTTTAC		 SELEX
Jolma et al.(2013)
FOXO6_2 		0.755 0.687
FOXO6
M03051_2.00 		Homo sapiens
TTTCCCCACACGMC
GKCGTGTGGGGAAA		 SELEX
Jolma et al.(2013)
FOXO6_3 		0.755 0.687
Foxo1
M00795_2.00 		Mus musculus
NRWMAACAN
NTGTTKWYN		 PBM
Weirauch et al.(2013)
pTH3846 		0.747 0.711
FOXO1
M03022_2.00 		Homo sapiens
RTAAACAW
WTGTTTAY		 SELEX
Jolma et al.(2013)
FOXO1_1 		0.747 0.711
FOXO1
M03023_2.00 		Homo sapiens
GTAAACATGTTTAY
RTAAACATGTTTAC		 SELEX
Jolma et al.(2013)
FOXO1_2 		0.747 0.711
FOXO1
M03024_2.00 		Homo sapiens
TTTCCCCACACD
HGTGTGGGGAAA		 SELEX
Jolma et al.(2013)
FOXO1_3 		0.747 0.711
Foxo1
M08122_2.00 		Mus musculus
DGTAAACARSH
DSYTGTTTACH		 ChIP-seq
Mathelier et al.(2014)
MA0480.1 		0.747 0.711
FOXO1
M09091_2.00 		Homo sapiens
NRDAAACAVVVN
NBBBTGTTTHYN		 Misc
Kulakovskiy et al.(2013)
FOXO1_HUMAN.H11MO.0.A 		0.747 0.711
Foxo1
M09108_2.00 		Mus musculus
RWMAACAVVN
NBBTGTTKWY		 Misc
Kulakovskiy et al.(2013)
FOXO1_MOUSE.H11MO.0.A 		0.747 0.711
Foxo1
M09547_2.00 		Mus musculus
GTAAACAV
BTGTTTAC		 Misc
Heinz et al.(2010)
RAW-Foxo1_Fan_et_al. 		0.747 0.711
FOXO1
M10549_2.00 		Homo sapiens
NVWAAACAMN
NKTGTTTWBN		 Transfac
Matys et al.(2006)
V$FOXO1_01 		0.747 0.711
FOXO1
M10550_2.00 		Homo sapiens
VNHGTAAACAANHH
DDNTTGTTTACDNB		 Transfac
Matys et al.(2006)
V$FOXO1_02 		0.747 0.711
FOXO1
M10551_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$FOXO1_03 		0.747 0.711
FOXO1
M10552_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$FOXO1_04 		0.747 0.711
FOXO1
M10553_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$FOXO1A_Q3 		0.747 0.711
FOXO1
M10554_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$FOXO1A_Q5 		0.747 0.711
foxo
M06198_2.00 		Drosophila melanogaster
YVRWAAACA
TGTTTWYBR		 B1H
Zhu et al.(2011)
foxo_SANGER_10_FBgn0038197 		0.739 0.771
For this family, TFs with SR scores > 0.664 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M01989_2.00 Forkhead 50 140

DNA Binding Domains

Protein ID Domain From To Sequence
R13H8.1a Forkhead 165 255
R13H8.1b.1 Forkhead 143 233
R13H8.1b.2 Forkhead 143 233
R13H8.1c.1 Forkhead 145 235
R13H8.1c.2 Forkhead 145 235
R13H8.1d Forkhead 122 212
R13H8.1f Forkhead 152 242
R13H8.1g Forkhead 1 49
R13H8.1h Forkhead 176 266

Links

Other Forkhead family TFs
Other Caenorhabditis elegans TFs

284 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CRE28480 Caenorhabditis remanei CRE28480 I 0.834
L892_g28207 Steinernema scapterisci L892_g28207 I 0.832
SMUV_0000148401 Syphacia muris SMUV_0000148401 I 0.827
CBN07990 Caenorhabditis brenneri CBN07990 I 0.826
CBG12825 Caenorhabditis briggsae CBG12825 I 0.821
CJA04896 Caenorhabditis japonica CJA04896 I 0.821
HCOI00585700 Haemonchus contortus HCOI00585700 I 0.808
LOAG_18029 Loa loa LOAG_18029 I 0.808
Bm5392 Brugia malayi Bm5392 I 0.808
SPAL_0000140300 Strongyloides papillosus SPAL_0000140300 I 0.804
PTRK_0000872800 Parastrongyloides trichosuri PTRK_0000872800 I 0.804
SSTP_0001206800 Strongyloides stercoralis SSTP_0001206800 I 0.804
SVE_0221800 Strongyloides venezuelensis SVE_0221800 I 0.804
TCNE_0000984601 Toxocara canis TCNE_0000984601 I 0.801
ASU_05583 Ascaris suum ASU_05583 I 0.801
BGLB012045 Biomphalaria glabrata BGLB012045 I 0.801
ALUE_0000559201 Ascaris lumbricoides ALUE_0000559201 I 0.801
CGI_10007980 Crassostrea gigas CGI_10007980 I 0.801
ACOC_0001009801 Angiostrongylus costaricensis ACOC_0001009801 I 0.801
L596_g21623 Steinernema carpocapsae L596_g21623 I 0.800
L889_g26642 Steinernema feltiae L889_g26642 I 0.800
L893_g8649 Steinernema glaseri L893_g8649 I 0.799
D918_00830 Trichuris suis D918_00830 I 0.797
TTRE_0000521201 Trichuris trichiura TTRE_0000521201 I 0.797
TMUE_s0073000800 Trichuris muris TMUE_s0073000800 I 0.797
D917_06987 Trichinella nativa D917_06987 I 0.797
EFV53044 Trichinella spiralis EFV53044 I 0.797
snap_masked-nMf.1.1.scaf25582-processed-gene-0.1 Meloidogyne floridensis snap_masked-nMf.1.1.scaf25582-processed-gene-0.1 I 0.795
TriadG25137 Trichoplax adhaerens TriadG25137 I 0.793
MhA1_Contig353.frz3.fgene4 Meloidogyne hapla MhA1_Contig353.frz3.fgene4 I 0.788
ACYPI008827 Acyrthosiphon pisum ACYPI008827 I 0.787
GPLIN_001276900 Globodera pallida GPLIN_001276900 I 0.786
foxo1b Gasterosteus aculeatus ENSGACG00000020424 I 0.785
foxo1b Tetraodon nigroviridis ENSTNIG00000011758 I 0.785
foxo1b Takifugu rubripes ENSTRUG00000016495 I 0.785
ENSPFOG00000008773 Poecilia formosa ENSPFOG00000008773 I 0.785
ENSONIG00000005435 Oreochromis niloticus ENSONIG00000005435 I 0.785
ENSXMAG00000012178 Xiphophorus maculatus ENSXMAG00000012178 I 0.785
ENSAMXG00000008913 Astyanax mexicanus ENSAMXG00000008913 I 0.784
FOXO1 Anolis carolinensis ENSACAG00000016628 I 0.784
foxo3a Danio rerio ENSDARG00000023058 I 0.784
ENSAMXG00000000626 Astyanax mexicanus ENSAMXG00000000626 I 0.784
ENSONIG00000013292 Oreochromis niloticus ENSONIG00000013292 I 0.780
ENSONIG00000016186 Oreochromis niloticus ENSONIG00000016186 I 0.780
ENSAMXG00000001483 Astyanax mexicanus ENSAMXG00000001483 I 0.780
ENSPFOG00000019537 Poecilia formosa ENSPFOG00000019537 I 0.780
foxo1a Gasterosteus aculeatus ENSGACG00000011918 I 0.780
si:ch211-206a7.2 Oryzias latipes ENSORLG00000008208 I 0.780
foxo1 Oryzias latipes ENSORLG00000003107 I 0.780
si:ch211-206a7.2 Gasterosteus aculeatus ENSGACG00000007819 I 0.780
ENSONIG00000010293 Oreochromis niloticus ENSONIG00000010293 I 0.780
foxo3a Gasterosteus aculeatus ENSGACG00000011645 I 0.780
ENSPFOG00000015252 Poecilia formosa ENSPFOG00000015252 I 0.780
ENSPFOG00000014431 Poecilia formosa ENSPFOG00000014431 I 0.780
ENSLACG00000016385 Latimeria chalumnae ENSLACG00000016385 I 0.780
ENSLOCG00000008807 Lepisosteus oculatus ENSLOCG00000008807 I 0.780
si:dkey-11f5.5 Oryzias latipes ENSORLG00000014219 I 0.780
foxo3 Oryzias latipes ENSORLG00000013450 I 0.780
ENSLACG00000010206 Latimeria chalumnae ENSLACG00000010206 I 0.780
ENSPFOG00000005111 Poecilia formosa ENSPFOG00000005111 I 0.780
ENSGMOG00000002305 Gadus morhua ENSGMOG00000002305 I 0.780
ENSONIG00000005674 Oreochromis niloticus ENSONIG00000005674 I 0.780
ENSPFOG00000006480 Poecilia formosa ENSPFOG00000006480 I 0.780
ENSGMOG00000012748 Gadus morhua ENSGMOG00000012748 I 0.780
ENSLOCG00000003028 Lepisosteus oculatus ENSLOCG00000003028 I 0.780
FOXO1 Taeniopygia guttata ENSTGUG00000012008 I 0.780
ENSXMAG00000014478 Xiphophorus maculatus ENSXMAG00000014478 I 0.780
ENSONIG00000000638 Oreochromis niloticus ENSONIG00000000638 I 0.780
foxo1b Danio rerio ENSDARG00000061549 I 0.780
foxo1a Danio rerio ENSDARG00000099555 I 0.780
si:ch211-206a7.2 Danio rerio ENSDARG00000024619 I 0.780
ENSXMAG00000015269 Xiphophorus maculatus ENSXMAG00000015269 I 0.780
Pvit_12542 Pogona vitticeps Pvit_12542 I 0.780
foxo6.S Xenopus laevis XB-GENE-6259110 I 0.780
XP_002939401 Xenopus tropicalis XP_002939401 I 0.780
ENSXMAG00000000408 Xiphophorus maculatus ENSXMAG00000000408 I 0.780
ENSXMAG00000003269 Xiphophorus maculatus ENSXMAG00000003269 I 0.780
foxo3a Tetraodon nigroviridis ENSTNIG00000019314 I 0.780
si:ch211-206a7.2 Tetraodon nigroviridis ENSTNIG00000009804 I 0.780
FOXO3 Taeniopygia guttata ENSTGUG00000012135 I 0.780
ENSFALG00000001139 Ficedula albicollis ENSFALG00000001139 I 0.780
si:dkey-11f5.5 Takifugu rubripes ENSTRUG00000001776 I 0.780
ENSAMXG00000009884 Astyanax mexicanus ENSAMXG00000009884 I 0.780
si:ch211-206a7.2 Takifugu rubripes ENSTRUG00000009753 I 0.780
foxo1a Takifugu rubripes ENSTRUG00000014453 I 0.780
foxo3a Takifugu rubripes ENSTRUG00000004868 I 0.780
Foxo4 Mus musculus ENSMUSG00000042903 D 0.779
ENSOARG00000016065 Ovis aries ENSOARG00000016065 I 0.779
FOXO4 Ochotona princeps ENSOPRG00000004618 I 0.779
FOXO4 Sorex araneus ENSSARG00000008583 I 0.779
ENSMPUG00000004635 Mustela putorius furo ENSMPUG00000004635 I 0.779
ENSBTAP00000006418-D1 Bos grunniens ENSBTAP00000006418-D1 I 0.779
ENSP00000363377 Macaca fascicularis ENSP00000363377 I 0.779
ENSSTOG00000014587 Ictidomys tridecemlineatus ENSSTOG00000014587 I 0.779
FOXO4 Sus scrofa ENSSSCG00000012399 I 0.779
Foxo4 Rattus norvegicus ENSRNOG00000033316 I 0.779
Myotis_brandtii_FOXO4_10007300 Myotis brandtii Myotis_brandtii_FOXO4_10007300 I 0.779
ENSPPYG00000020444 Pongo abelii ENSPPYG00000020444 I 0.779
ENSPANG00000026427 Papio anubis ENSPANG00000026427 I 0.779
FOXO4 Felis catus ENSFCAG00000031493 I 0.779
FOXO4 Canis familiaris ENSCAFG00000016925 I 0.779
ENSCSAG00000011533 Chlorocebus sabaeus ENSCSAG00000011533 I 0.779
FOXO4 Callithrix jacchus ENSCJAG00000013651 I 0.779
FOXO4 Cavia porcellus ENSCPOG00000004771 I 0.779
Foxo4 Dipodomys ordii ENSDORG00000002179 I 0.779
ENSMEUG00000012979 Macropus eugenii ENSMEUG00000012979 I 0.779
ENSAMEG00000015896 Ailuropoda melanoleuca ENSAMEG00000015896 I 0.779
FOXO4 Myotis lucifugus ENSMLUG00000029037 I 0.779
FOXO4 Loxodonta africana ENSLAFG00000028324 I 0.779
FOXO4 Homo sapiens ENSG00000184481 D 0.779
FOXO4 Bos taurus ENSBTAG00000004879 I 0.779
GB48301 Apis mellifera GB48301 I 0.776
foxo1 Xenopus tropicalis XB-GENE-482528 I 0.775
foxo1.L Xenopus laevis XB-GENE-482532 I 0.775
foxo1b Oryzias latipes ENSORLG00000007715 I 0.774
foxo4 Xenopus tropicalis XB-GENE-480655 I 0.774
foxo4.L Xenopus laevis XB-GENE-6448195 I 0.774
NV14158 Nasonia vitripennis NV14158 I 0.772
FOXO4 Anolis carolinensis ENSACAG00000015254 I 0.772
Pvit_05359 Pogona vitticeps Pvit_05359 I 0.772
Ogr12016 Ophisaurus gracilis Ogr12016 I 0.771
foxo4 Tetraodon nigroviridis ENSTNIG00000016816 I 0.770
foxo4 Gasterosteus aculeatus ENSGACG00000017029 I 0.770
ENSONIG00000005449 Oreochromis niloticus ENSONIG00000005449 I 0.770
foxo4 Takifugu rubripes ENSTRUG00000012453 I 0.770
ENSXMAG00000013124 Xiphophorus maculatus ENSXMAG00000013124 I 0.769
ENSPFOG00000008795 Poecilia formosa ENSPFOG00000008795 I 0.769
si:dkey-11f5.5 Danio rerio ENSDARG00000100486 I 0.769
DME_0000896101 Dracunculus medinensis DME_0000896101 I 0.768
ENSAMXG00000008321 Astyanax mexicanus ENSAMXG00000008321 I 0.766
FOXO3 Callithrix jacchus ENSCJAG00000005929 I 0.766
ENSGMOG00000002885 Gadus morhua ENSGMOG00000002885 I 0.765
SPU_009178 Strongylocentrotus purpuratus SPU_009178 I 0.765
SPU_028698 Strongylocentrotus purpuratus SPU_028698 I 0.765
foxo4 Danio rerio ENSDARG00000055792 I 0.765
XP_002167754.1 Hydra magnipapillata XP_002167754.1 I 0.764
FOXO3 Homo sapiens ENSG00000118689 D 0.759
ENSSTOG00000022339 Ictidomys tridecemlineatus ENSSTOG00000022339 I 0.759
FOXO3 Sus scrofa ENSSSCG00000004387 I 0.759
FOXO3 Pan troglodytes ENSPTRG00000018476 I 0.759
FOXO3 Pteropus vampyrus ENSPVAG00000001137 I 0.759
Foxo3 Rattus norvegicus ENSRNOG00000000299 I 0.759
ENSCSAG00000015174 Chlorocebus sabaeus ENSCSAG00000015174 I 0.759
FOXO3 Cavia porcellus ENSCPOG00000021906 I 0.759
FOXO3 Canis familiaris ENSCAFG00000003783 I 0.759
FOXO3 Bos taurus ENSBTAG00000011234 I 0.759
ENSAMEG00000008158 Ailuropoda melanoleuca ENSAMEG00000008158 I 0.759
ENSP00000339527 Macaca fascicularis ENSP00000339527 I 0.759
ENSBTAP00000014920-D1 Bos grunniens ENSBTAP00000014920-D1 I 0.759
ENSDORG00000013871 Dipodomys ordii ENSDORG00000013871 I 0.759
FOXO3 Tursiops truncatus ENSTTRG00000017232 I 0.759
ENSPPYG00000016896 Pongo abelii ENSPPYG00000016896 I 0.759
FOXO3 Echinops telfairi ENSETEG00000004130 I 0.759
FOXO3 Dasypus novemcinctus ENSDNOG00000005257 I 0.759
Foxo3 Mus musculus ENSMUSG00000048756 D 0.759
FOXO3 Loxodonta africana ENSLAFG00000005834 I 0.759
ENSPANG00000015284 Papio anubis ENSPANG00000015284 I 0.759
ENSMICG00000014311 Microcebus murinus ENSMICG00000014311 I 0.759
FOXO3 Macaca mulatta ENSMMUG00000020369 I 0.759
ENSNLEG00000012446 Nomascus leucogenys ENSNLEG00000012446 I 0.759
FOXO3 Oryctolagus cuniculus ENSOCUG00000010471 I 0.759
FOXO3 Otolemur garnettii ENSOGAG00000027196 I 0.759
FOXO3 Procavia capensis ENSPCAG00000008041 I 0.759
ENSMPUG00000009847 Mustela putorius furo ENSMPUG00000009847 I 0.759
FOXO3 Gorilla gorilla ENSGGOG00000003517 I 0.759
ENSFALG00000008600 Ficedula albicollis ENSFALG00000008600 I 0.758
tetur18g03070 Tetranychus urticae tetur18g03070 I 0.758
ENSMEUG00000014523 Macropus eugenii ENSMEUG00000014523 I 0.757
FOXO3 Myotis lucifugus ENSMLUG00000002590 I 0.757
Sakowv30038013m.g Saccoglossus kowalevskii Sakowv30038013m.g I 0.757
FOXO4 Pan troglodytes ENSPTRG00000022004 I 0.756
ENSPSIG00000007776 Pelodiscus sinensis ENSPSIG00000007776 I 0.755
FOXO6 Gorilla gorilla ENSGGOG00000026271 I 0.755
ENSTTRG00000005580 Tursiops truncatus ENSTTRG00000005580 I 0.755
FOXO6 Callithrix jacchus ENSCJAG00000003070 I 0.755
FOXO6 Dasypus novemcinctus ENSDNOG00000032075 I 0.755
FOXO4 Otolemur garnettii ENSOGAG00000025297 I 0.755
HelroG64772 Helobdella robusta HelroG64772 I 0.755
ENSOARG00000020357 Ovis aries ENSOARG00000020357 I 0.755
Myotis_brandtii_Foxo6_10016755 Myotis brandtii Myotis_brandtii_Foxo6_10016755 I 0.755
FOXO6 Cavia porcellus ENSCPOG00000022256 I 0.755
foxo3b Danio rerio ENSDARG00000042904 I 0.755
ENSPANG00000000435 Papio anubis ENSPANG00000000435 I 0.755
ENSLOCG00000016605 Lepisosteus oculatus ENSLOCG00000016605 I 0.755
ENSCSAG00000001157 Chlorocebus sabaeus ENSCSAG00000001157 I 0.755
FOXO6 Ochotona princeps ENSOPRG00000003070 I 0.755
ENSAMXG00000014766 Astyanax mexicanus ENSAMXG00000014766 I 0.755
FOXO6 Monodelphis domestica ENSMODG00000017333 I 0.755
FOXO6 Homo sapiens ENSG00000204060 D 0.755
ENSMICG00000013973 Microcebus murinus ENSMICG00000013973 I 0.755
foxo3b Gasterosteus aculeatus ENSGACG00000008910 I 0.755
ENSSHAG00000003662 Sarcophilus harrisii ENSSHAG00000003662 I 0.755
ENSSTOG00000026753 Ictidomys tridecemlineatus ENSSTOG00000026753 I 0.755
Foxo6 Mus musculus ENSMUSG00000052135 D 0.755
ENSFCAG00000024925 Felis catus ENSFCAG00000024925 I 0.755
foxo3b Takifugu rubripes ENSTRUG00000001458 I 0.755
FOXO6 Otolemur garnettii ENSOGAG00000028037 I 0.755
Foxo6 Rattus norvegicus ENSRNOG00000032639 I 0.755
FOXO6 Procavia capensis ENSPCAG00000013290 I 0.755
ENSMPUG00000014082 Mustela putorius furo ENSMPUG00000014082 I 0.755
FOXO3 Monodelphis domestica ENSMODG00000017994 I 0.754
OFLC_0000193701 Onchocerca flexuosa OFLC_0000193701 I 0.753
nOo.2.0.1.g07140 Onchocerca ochengi nOo.2.0.1.g07140 I 0.753
WBGene00237302 Onchocerca volvulus WBGene00237302 I 0.753
nOo.2.0.1.g05753 Onchocerca ochengi nOo.2.0.1.g05753 I 0.753
nDi.2.2.2.g01961 Dirofilaria immitis nDi.2.2.2.g01961 I 0.753
BTMF_0000986201 Brugia timori BTMF_0000986201 I 0.753
WUBG_10392 Wuchereria bancrofti WUBG_10392 I 0.753
HelroG136569 Helobdella robusta HelroG136569 I 0.752
ENSGMOG00000005771 Gadus morhua ENSGMOG00000005771 I 0.752
RSKR_0000006600 Rhabditophanes kr3021 RSKR_0000006600 I 0.751
ENSLACG00000009595 Latimeria chalumnae ENSLACG00000009595 I 0.750
FOXO1 Monodelphis domestica ENSMODG00000010342 I 0.747
FOXO1 Bos taurus ENSBTAG00000044105 I 0.747
Foxo1 Mus musculus ENSMUSG00000044167 D 0.747
ENSAMEG00000011714 Ailuropoda melanoleuca ENSAMEG00000011714 I 0.747
FOXO1 Otolemur garnettii ENSOGAG00000029027 I 0.747
FOXO1 Pan troglodytes ENSPTRG00000005806 I 0.747
FOXO1 Callithrix jacchus ENSCJAG00000017816 I 0.747
FOXO1 Macaca mulatta ENSMMUG00000030780 I 0.747
FOXO1 Gorilla gorilla ENSGGOG00000008104 I 0.747
FOXO1 Ornithorhynchus anatinus ENSOANG00000015514 I 0.747
ENSNLEG00000001156 Nomascus leucogenys ENSNLEG00000001156 I 0.747
ENSCSAG00000017842 Chlorocebus sabaeus ENSCSAG00000017842 I 0.747
FOXO1 Ochotona princeps ENSOPRG00000008735 I 0.747
ENSPPYG00000005304 Pongo abelii ENSPPYG00000005304 I 0.747
FOXO1 Homo sapiens ENSG00000150907 D 0.747
ENSPCAG00000005483 Procavia capensis ENSPCAG00000005483 I 0.747
Foxo1 Rattus norvegicus ENSRNOG00000013397 I 0.747
FOXO1 Sus scrofa ENSSSCG00000009370 I 0.747
ENSPANG00000016677 Papio anubis ENSPANG00000016677 I 0.747
ENSSTOG00000009697 Ictidomys tridecemlineatus ENSSTOG00000009697 I 0.747
si:dkey-11f5.5 Gasterosteus aculeatus ENSGACG00000013956 I 0.744
FOXO1 Canis familiaris ENSCAFG00000005965 I 0.740
FOXO1 Pteropus vampyrus ENSPVAG00000012042 I 0.740
foxo Drosophila pseudoobscura FBgn0076264 I 0.739
AGAP001577 Anopheles gambiae AGAP001577 I 0.739
foxo Drosophila melanogaster FBgn0038197 D 0.739
foxo Drosophila grimshawi FBgn0129734 I 0.739
MCINX004005 Melitaea cinxia MCINX004005 I 0.739
foxo Drosophila willistoni FBgn0224664 I 0.739
foxo Drosophila virilis FBgn0201557 I 0.739
foxo Drosophila mojavensis FBgn0144713 I 0.739
HelroG136557 Helobdella robusta HelroG136557 I 0.737
TCLT_0000249001 Thelazia callipaeda TCLT_0000249001 I 0.733
NV18212 Nasonia vitripennis NV18212 I 0.732
Aqu1.217829 Amphimedon queenslandica Aqu1.217829 I 0.725
ENSXMAG00000007378 Xiphophorus maculatus ENSXMAG00000007378 I 0.724
foxo3.L Xenopus laevis XB-GENE-945076 I 0.723
foxo3 Xenopus tropicalis XB-GENE-945072 I 0.723
Aqu1.211498 Amphimedon queenslandica Aqu1.211498 I 0.695
nLs.2.1.2.g00563 Litomosoides sigmodontis nLs.2.1.2.g00563 I 0.690
ENSCSAVG00000008339 Ciona savignyi ENSCSAVG00000008339 I 0.690
EBI_27500 Enterocytozoon bieneusi EBI_27500 I 0.683
nAv.1.0.1.g02965 Acanthocheilonema viteae nAv.1.0.1.g02965 I 0.683
M438DRAFT_70359 Aureobasidium pullulans M438DRAFT_70359 I 0.682
CAOG_01766 Capsaspora owczarzaki CAOG_01766 I 0.678
NechaG104145 Fusarium solani NechaG104145 I 0.676
estExt_fgenesh1_pm.C_sca_3_chr4_2_00404 Nectria haematococca estExt_fgenesh1_pm.C_sca_3_chr4_2_00404 I 0.676
SJAG_03143 Schizosaccharomyces japonicus SJAG_03143 I 0.673
AGAP000569 Anopheles gambiae AGAP000569 I 0.672
ACUA012815 Anopheles culicifacies ACUA012815 I 0.672
ACOM033517 Anopheles coluzzii ACOM033517 I 0.672
ENSONIG00000002167 Oreochromis niloticus ENSONIG00000002167 I 0.670
FOXJ3 Tetraodon nigroviridis ENSTNIG00000007159 I 0.670
ENSXMAG00000016662 Xiphophorus maculatus ENSXMAG00000016662 I 0.670
ENSPFOG00000009113 Poecilia formosa ENSPFOG00000009113 I 0.670
FOXJ3 Oryzias latipes ENSORLG00000004623 I 0.669
ENSLOCG00000014427 Lepisosteus oculatus ENSLOCG00000014427 I 0.669
FOXP3 Ornithorhynchus anatinus ENSOANG00000013584 I 0.668
NEMVEDRAFT_v1g120142 Nematostella vectensis NEMVEDRAFT_v1g120142 I 0.666
ENSOCUG00000027545 Oryctolagus cuniculus ENSOCUG00000027545 I 0.666
ENSNLEG00000001131 Nomascus leucogenys ENSNLEG00000001131 I 0.666
FOXO4 Dasypus novemcinctus ENSDNOG00000041132 I 0.665
EmuJ_000500800 Echinococcus multilocularis EmuJ_000500800 I 0.665
ECANG7_07717 Echinococcus canadensis ECANG7_07717 I 0.665
FVEG_08252 Fusarium verticillioides FVEG_08252 I 0.665
FOXG_01874 Fusarium oxysporum FOXG_01874 I 0.665
FFUJ_02919 Fusarium fujikuroi FFUJ_02919 I 0.665
ENSAMXG00000000184 Astyanax mexicanus ENSAMXG00000000184 I 0.664
DAPPUDRAFT_335438 Daphnia pulex DAPPUDRAFT_335438 I 0.664
SMAR010863 Strigamia maritima SMAR010863 I 0.664
ASIM_0001256201 Anisakis simplex ASIM_0001256201 I 0.040