HHAL010341-PA (Halyomorpha halys)
Forkhead

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00250 (Forkhead) IPR001766 HHAL010341-PA T189533_2.00 Misc (2018-Jan-19)
NCBI Gene Info:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
fd96Ca
M03743_2.00 		Drosophila melanogaster
WRWGYMAATATTKRCWYW
WRWGYMAATATTKRCWYW		 SELEX
Nitta et al.(2015)
fd96Ca_1 		0.760 0.867
Foxb1
M01983_2.00 		Mus musculus
TRTTKAYWYW
WRWRTMAAYA		 PBM
Weirauch et al.(2014)
pTH2808 		0.759 0.800
FOXB1
M03028_2.00 		Homo sapiens
GAATGACACRGCKV
BMGCYGTGTCATTC		 SELEX
Jolma et al.(2013)
FOXB1_1 		0.759 0.800
FOXB1
M03029_2.00 		Homo sapiens
WRWGTMAATATTKACWYW
WRWGTMAATATTKACWYW		 SELEX
Jolma et al.(2013)
FOXB1_2 		0.759 0.800
FOXB1
M03030_2.00 		Homo sapiens
WTRTTKACWTW
WAWGTMAAYAW		 SELEX
Jolma et al.(2013)
FOXB1_3 		0.759 0.800
FOXB1
M03031_2.00 		Homo sapiens
NTRTTTACW
WGTAAAYAN		 SELEX
Jolma et al.(2013)
FOXB1_4 		0.759 0.800
FOXB1
M04837_2.00 		Homo sapiens
NWRDGYMAATATTKRCWYWD
HWRWGYMAATATTKRCHYWN		 SELEX
Yin et al.(2017)
FOXB1_eDBD_HT-SELEX 		0.759 0.800
FOXB1
M04838_2.00 		Homo sapiens
NWRNGYMAATATTKRCDYWD
HWRHGYMAATATTKRCNYWN		 SELEX
Yin et al.(2017)
FOXB1_eDBD_Methyl-HT-SELEX 		0.759 0.800
lin-31
M00665_2.00 		Caenorhabditis elegans
NWRTAAAYANN
NNTRTTTAYWN		 PBM
Narasimhan et al.(2015)
pTH9116 		0.751 0.760
For this family, TFs with SR scores > 0.664 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
HHAL010341-PA Forkhead 1 79

Links

Other Forkhead family TFs
Other Halyomorpha halys TFs

216 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CLEC010021 Cimex lectularius CLEC010021 I 0.809
RPRC007940 Rhodnius prolixus RPRC007940 I 0.808
AFAF016495 Anopheles farauti AFAF016495 I 0.792
AFUN003012 Anopheles funestus AFUN003012 I 0.792
AMAM006044 Anopheles maculatus AMAM006044 I 0.792
AMEC004215 Anopheles melas AMEC004215 I 0.792
AEPI003894 Anopheles epiroticus AEPI003894 I 0.792
ADIR003007 Anopheles dirus ADIR003007 I 0.792
AARA004408 Anopheles arabiensis AARA004408 I 0.792
AALB009714 Anopheles albimanus AALB009714 I 0.792
AATE015004 Anopheles atroparvus AATE015004 I 0.792
ACOM036957 Anopheles coluzzii ACOM036957 I 0.792
ACUA003219 Anopheles culicifacies ACUA003219 I 0.792
AMEM008897 Anopheles merus AMEM008897 I 0.792
AMIN002729 Anopheles minimus AMIN002729 I 0.792
ADAC001695 Anopheles darlingi ADAC001695 I 0.792
AQUA009497 Anopheles quadriannulatus AQUA009497 I 0.792
AGAP013297 Anopheles gambiae AGAP013297 I 0.792
ASIS012327 Anopheles sinensis ASIS012327 I 0.792
ASTEI00712 Anopheles stephensi ASTEI00712 I 0.792
ENSPFOG00000020934 Poecilia formosa ENSPFOG00000020934 I 0.791
ACYPI001196 Acyrthosiphon pisum ACYPI001196 I 0.772
PHUM202880 Pediculus humanus PHUM202880 I 0.772
L798_04274 Zootermopsis nevadensis L798_04274 I 0.771
PHUM202670 Pediculus humanus PHUM202670 I 0.771
TC013630 Tribolium castaneum TC013630 I 0.771
TC014185 Tribolium castaneum TC014185 I 0.765
YQE_02832 Dendroctonus ponderosae YQE_02832 I 0.765
LDEC021031 Leptinotarsa decemlineata LDEC021031 I 0.765
BGIBMGA003641 Bombyx mori BGIBMGA003641 I 0.761
BGIBMGA003547 Bombyx mori BGIBMGA003547 I 0.761
HMEL014116 Heliconius melpomene HMEL014116 I 0.761
HMEL014115 Heliconius melpomene HMEL014115 I 0.761
KGM_02399 Danaus plexippus KGM_02399 I 0.761
maker-nMf.1.1.scaf03071-snap-gene-0.6 Meloidogyne floridensis maker-nMf.1.1.scaf03071-snap-gene-0.6 I 0.761
GK13404 Drosophila willistoni FBgn0215413 I 0.760
GF17887 Drosophila ananassae FBgn0094905 I 0.760
fd96Ca Drosophila melanogaster FBgn0004897 D 0.760
PPAI002320 Phlebotomus papatasi PPAI002320 I 0.760
GJ23595 Drosophila virilis FBgn0210692 I 0.760
GG11359 Drosophila erecta FBgn0103659 I 0.760
GE23556 Drosophila yakuba FBgn0240732 I 0.760
GM17800 Drosophila sechellia FBgn0172707 I 0.760
GH18035 Drosophila grimshawi FBgn0125503 I 0.760
GI23781 Drosophila mojavensis FBgn0146506 I 0.760
GL21898 Drosophila persimilis FBgn0159491 I 0.760
AAEL002951 Aedes aegypti AAEL002951 I 0.760
LLOJ001046 Lutzomyia longipalpis LLOJ001046 I 0.760
MDOA004789 Musca domestica MDOA004789 I 0.760
ENSPPYG00000006525 Pongo abelii ENSPPYG00000006525 I 0.759
ENSPSIG00000000517 Pelodiscus sinensis ENSPSIG00000000517 I 0.759
ENSSHAG00000013988 Sarcophilus harrisii ENSSHAG00000013988 I 0.759
Gfo_R008826 Geospiza fortis Gfo_R008826 I 0.759
FOXB1 Pan troglodytes ENSPTRG00000007131 I 0.759
ENSPANG00000000869 Papio anubis ENSPANG00000000869 I 0.759
ENSONIG00000020607 Oreochromis niloticus ENSONIG00000020607 I 0.759
ENSONIG00000020969 Oreochromis niloticus ENSONIG00000020969 I 0.759
foxb1 Oryzias latipes ENSORLG00000007576 I 0.759
ENSSTOG00000020458 Ictidomys tridecemlineatus ENSSTOG00000020458 I 0.759
ENSPFOG00000019893 Poecilia formosa ENSPFOG00000019893 I 0.759
FOXB1 Tetraodon nigroviridis ENSTNIG00000008393 I 0.759
Brh_R004678 Buceros rhinoceros Brh_R004678 I 0.759
Afo_R009411 Aptenodytes forsteri Afo_R009411 I 0.759
Aan_R015086 Calypte anna Aan_R015086 I 0.759
FOXB1 Otolemur garnettii ENSOGAG00000007643 I 0.759
ENSMMUP00000001831 Macaca fascicularis ENSMMUP00000001831 I 0.759
ENSP00000365898-D1 Bos grunniens ENSP00000365898-D1 I 0.759
foxb1a Takifugu rubripes ENSTRUG00000003702 I 0.759
FOXB1 Takifugu rubripes ENSTRUG00000011290 I 0.759
ENSTSYG00000006726 Tarsius syrichta ENSTSYG00000006726 I 0.759
FOXB1 Taeniopygia guttata ENSTGUG00000005409 I 0.759
FOXB1 Takifugu rubripes ENSTRUG00000011299 I 0.759
ENSAPLG00000006208 Anas platyrhynchos ENSAPLG00000006208 I 0.759
FOXB1 Bos taurus ENSBTAG00000019114 I 0.759
ENSAMXG00000025385 Astyanax mexicanus ENSAMXG00000025385 I 0.759
ENSAMXG00000003780 Astyanax mexicanus ENSAMXG00000003780 I 0.759
FOXB1 Monodelphis domestica ENSMODG00000024647 I 0.759
ENSAMEG00000019472 Ailuropoda melanoleuca ENSAMEG00000019472 I 0.759
FOXB1 Macaca mulatta ENSMMUG00000001379 I 0.759
FOXB1 Microcebus murinus ENSMICG00000017700 I 0.759
ENSCSAG00000019740 Chlorocebus sabaeus ENSCSAG00000019740 I 0.759
FOXB1 Callithrix jacchus ENSCJAG00000023331 I 0.759
ENSLOCG00000017957 Lepisosteus oculatus ENSLOCG00000017957 I 0.759
FOXB1 Canis familiaris ENSCAFG00000025176 I 0.759
FOXB1 Gallus gallus ENSGALG00000027498 I 0.759
foxb1b Danio rerio ENSDARG00000053650 I 0.759
foxb1a Danio rerio ENSDARG00000089042 I 0.759
ENSLACG00000017859 Latimeria chalumnae ENSLACG00000017859 I 0.759
ENSGMOG00000020232 Gadus morhua ENSGMOG00000020232 I 0.759
FOXB1 Felis catus ENSFCAG00000026520 I 0.759
FOXB1 Homo sapiens ENSG00000171956 D 0.759
ENSOARG00000000893 Ovis aries ENSOARG00000000893 I 0.759
FOXB1 Gorilla gorilla ENSGGOG00000024062 I 0.759
FOXB1 Gasterosteus aculeatus ENSGACG00000010700 I 0.759
ENSNLEG00000011675 Nomascus leucogenys ENSNLEG00000011675 I 0.759
ENSGMOG00000020283 Gadus morhua ENSGMOG00000020283 I 0.759
FOXB1 Dasypus novemcinctus ENSDNOG00000023596 I 0.759
ENSMPUG00000019446 Mustela putorius furo ENSMPUG00000019446 I 0.759
FOXB1 Equus caballus ENSECAG00000004144 I 0.759
ENSFALG00000012555 Ficedula albicollis ENSFALG00000012555 I 0.759
Foxb1 Mus musculus ENSMUSG00000059246 D 0.759
FOXB1 Cavia porcellus ENSCPOG00000020128 I 0.759
foxb2 Tetraodon nigroviridis ENSTNIG00000015811 I 0.758
ENSPFOG00000020822 Poecilia formosa ENSPFOG00000020822 I 0.758
foxb2 Oryzias latipes ENSORLG00000005726 I 0.758
foxb2 Takifugu rubripes ENSTRUG00000002220 I 0.758
BXY_1124000 Bursaphelenchus xylophilus BXY_1124000 I 0.751
lin-31 Caenorhabditis elegans WBGene00003017 D 0.751
LCUP010877 Lucilia cuprina LCUP010877 I 0.744
foxb1a Gasterosteus aculeatus ENSGACG00000017597 I 0.743
DME_0000946301 Dracunculus medinensis DME_0000946301 I 0.734
L893_g32465 Steinernema glaseri L893_g32465 I 0.733
L889_g13352 Steinernema feltiae L889_g13352 I 0.733
PTRK_0001493600 Parastrongyloides trichosuri PTRK_0001493600 I 0.733
RSKR_0000534800 Rhabditophanes kr3021 RSKR_0000534800 I 0.733
L596_g12640 Steinernema carpocapsae L596_g12640 I 0.733
NECAME_06653 Necator americanus NECAME_06653 I 0.733
HCOI01789800 Haemonchus contortus HCOI01789800 I 0.733
ACAC_0000134501 Angiostrongylus cantonensis ACAC_0000134501 I 0.733
HPBE_0000783201 Heligmosomoides bakeri HPBE_0000783201 I 0.733
ACOC_0000941501 Angiostrongylus costaricensis ACOC_0000941501 I 0.733
NBR_0000031301 Nippostrongylus brasiliensis NBR_0000031301 I 0.733
SSTP_0001021200 Strongyloides stercoralis SSTP_0001021200 I 0.733
SVE_0297700 Strongyloides venezuelensis SVE_0297700 I 0.733
SPAL_0001167300 Strongyloides papillosus SPAL_0001167300 I 0.733
L892_g11556 Steinernema scapterisci L892_g11556 I 0.733
TTRE_0000632801 Trichuris trichiura TTRE_0000632801 I 0.731
D918_01192 Trichuris suis D918_01192 I 0.731
ASIM_0002015101 Anisakis simplex ASIM_0002015101 I 0.730
BTMF_0000846601 Brugia timori BTMF_0000846601 I 0.729
ASU_09508 Ascaris suum ASU_09508 I 0.729
SPU_004551 Strongylocentrotus purpuratus SPU_004551 I 0.729
WUBG_04707 Wuchereria bancrofti WUBG_04707 I 0.729
EEL_0000659801 Elaeophora elaphi EEL_0000659801 I 0.728
WBGene00246832 Onchocerca volvulus WBGene00246832 I 0.728
TCLT_0000530701 Thelazia callipaeda TCLT_0000530701 I 0.728
CJA18631 Caenorhabditis japonica CJA18631 I 0.728
LOAG_08523 Loa loa LOAG_08523 I 0.728
CPIJ013077 Culex quinquefasciatus CPIJ013077 I 0.727
CpipJ_CPIJ013077 Culex pipiens CpipJ_CPIJ013077 I 0.727
DAPPUDRAFT_7975 Daphnia pulex DAPPUDRAFT_7975 I 0.727
ENSPMAG00000010234 Petromyzon marinus ENSPMAG00000010234 I 0.726
Ogr16895 Ophisaurus gracilis Ogr16895 I 0.726
CAD31848 Xenopus laevis CAD31848 I 0.726
foxb2 Gasterosteus aculeatus ENSGACG00000007973 I 0.726
foxb1.S Xenopus laevis XB-GENE-1018260 I 0.726
foxb1 Xenopus tropicalis XB-GENE-1018255 I 0.726
ENSAMXG00000026024 Astyanax mexicanus ENSAMXG00000026024 I 0.726
ENSLOCG00000017539 Lepisosteus oculatus ENSLOCG00000017539 I 0.726
ENSLACG00000014889 Latimeria chalumnae ENSLACG00000014889 I 0.726
ENSONIG00000020990 Oreochromis niloticus ENSONIG00000020990 I 0.726
foxb2 Danio rerio ENSDARG00000037475 I 0.726
Alligator_sinensis_CCG013377.1 Alligator sinensis Alligator_sinensis_CCG013377.1 I 0.726
SMUV_0000222901 Syphacia muris SMUV_0000222901 I 0.725
Sakowv30030656m.g Saccoglossus kowalevskii Sakowv30030656m.g I 0.723
CGI_10011405 Crassostrea gigas CGI_10011405 I 0.723
Ocbimv22011663m.g Octopus bimaculoides Ocbimv22011663m.g I 0.723
ENSGMOG00000020422 Gadus morhua ENSGMOG00000020422 I 0.722
Hsal_02007--XP_001120879.1_APIME Harpegnathos saltator Hsal_02007--XP_001120879.1_APIME I 0.722
NV15918 Nasonia vitripennis NV15918 I 0.722
GB41986 Apis mellifera GB41986 I 0.722
GI23783 Drosophila mojavensis FBgn0146508 I 0.721
LotgiG186344 Lottia gigantea LotgiG186344 I 0.719
CBG18439 Caenorhabditis briggsae CBG18439 I 0.719
BGLB006567 Biomphalaria glabrata BGLB006567 I 0.719
CRE20476 Caenorhabditis remanei CRE20476 I 0.719
ACYPI41428 Acyrthosiphon pisum ACYPI41428 I 0.718
LCUP016832 Lucilia cuprina LCUP016832 I 0.717
GK13405 Drosophila willistoni FBgn0215414 I 0.715
ENSOARG00000012458 Ovis aries ENSOARG00000012458 I 0.711
FOXB2 Otolemur garnettii ENSOGAG00000031210 I 0.711
ENSACAG00000023403 Anolis carolinensis ENSACAG00000023403 I 0.711
ENSPANG00000024937 Papio anubis ENSPANG00000024937 I 0.711
ENSPPYG00000019307 Pongo abelii ENSPPYG00000019307 I 0.711
ENSOANG00000021049 Ornithorhynchus anatinus ENSOANG00000021049 I 0.711
ENSMPUG00000012521 Mustela putorius furo ENSMPUG00000012521 I 0.711
Foxb2 Mus musculus ENSMUSG00000056829 I 0.711
FOXB2 Choloepus hoffmanni ENSCHOG00000007726 I 0.711
Cmyd_10017037 Chelonia mydas Cmyd_10017037 I 0.711
Alligator_sinensis_CCG018219.1 Alligator sinensis Alligator_sinensis_CCG018219.1 I 0.711
ENSBTAP00000050460-D3 Bos grunniens ENSBTAP00000050460-D3 I 0.711
FOXB2 Vicugna pacos ENSVPAG00000002649 I 0.711
FOXB2 Tursiops truncatus ENSTTRG00000011568 I 0.711
FOXB2 Loxodonta africana ENSLAFG00000022363 I 0.711
FOXB2 Dasypus novemcinctus ENSDNOG00000041384 I 0.711
FOXB2 Homo sapiens ENSG00000204612 I 0.711
FOXB2 Gorilla gorilla ENSGGOG00000026109 I 0.711
FOXB2 Oryctolagus cuniculus ENSOCUG00000002111 I 0.711
FOXB2 Gallus gallus ENSGALG00000028819 I 0.711
Ogr19315 Ophisaurus gracilis Ogr19315 I 0.711
Pvit_12485 Pogona vitticeps Pvit_12485 I 0.711
FOXB2 Sus scrofa ENSSSCG00000005279 I 0.711
FOXB2 Monodelphis domestica ENSMODG00000012804 I 0.711
Foxb2 Rattus norvegicus ENSRNOG00000032137 I 0.711
FOXB2 Pan troglodytes ENSPTRG00000029242 I 0.711
FOXB2 Macaca mulatta ENSMMUG00000021769 I 0.711
ENSBTAG00000032983 Bos taurus ENSBTAG00000032983 I 0.711
FOXB2 Callithrix jacchus ENSCJAG00000008722 I 0.711
ENSAMEG00000005376 Ailuropoda melanoleuca ENSAMEG00000005376 I 0.711
ENSMICG00000003599 Microcebus murinus ENSMICG00000003599 I 0.711
FOXB2 Canis familiaris ENSCAFG00000001637 I 0.711
SNAPOd2T00013846001 Oikopleura dioica SNAPOd2T00013846001 I 0.701
GF17888 Drosophila ananassae FBgn0094906 I 0.700
GG11360 Drosophila erecta FBgn0103660 I 0.700
GM17802 Drosophila sechellia FBgn0172709 I 0.700
GE23557 Drosophila yakuba FBgn0240733 I 0.700
GL21899 Drosophila persimilis FBgn0159492 I 0.699
GA27944 Drosophila pseudoobscura FBgn0249307 I 0.699
CapteG225366 Capitella teleta CapteG225366 I 0.697
fd96Cb Drosophila melanogaster FBgn0004898 I 0.696
GD21173 Drosophila simulans FBgn0192624 I 0.696
ASIS002452 Anopheles sinensis ASIS002452 I 0.693
AATE009403 Anopheles atroparvus AATE009403 I 0.693
nRc.2.0.1.g20826 Romanomermis culicivorax nRc.2.0.1.g20826 I 0.690
MCINX009518 Melitaea cinxia MCINX009518 I 0.666
SMAR012068 Strigamia maritima SMAR012068 I 0.665