Grhl3 (Mus musculus)
Grainyhead

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF04516 (CP2) IPR007604 ENSMUSG00000037188 T199111_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in establishment of skin barrier and neural tube closure. Acts upstream of or within several processes, including morphogenesis of an epithelium; positive regulation of macromolecule metabolic process; and sensory organ development. Located in nucleus. Is expressed in several structures, including alimentary system; embryo ectoderm; genitourinary system; heart; and hindlimb. Used to study Van der Woude syndrome. Orthologous to human GRHL3 (grainyhead like transcription factor 3). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000101481 Grainyhead 215 421

Links

Other Grainyhead family TFs
Other Mus musculus TFs

63 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Grhl3 Dipodomys ordii ENSDORG00000001381 N 0.952
Myotis_brandtii_Grhl3_10029711 Myotis brandtii Myotis_brandtii_Grhl3_10029711 N 0.947
ENSPPYG00000001721 Pongo abelii ENSPPYG00000001721 N 0.943
GRHL3 Homo sapiens ENSG00000158055 N 0.943
ENSPANG00000024748 Papio anubis ENSPANG00000024748 N 0.943
ENSCSAG00000000939 Chlorocebus sabaeus ENSCSAG00000000939 N 0.943
GRHL3 Gorilla gorilla ENSGGOG00000001792 N 0.943
GRHL3 Pan troglodytes ENSPTRG00000000344 N 0.943
ENSP00000288955 Macaca fascicularis ENSP00000288955 N 0.943
GRHL3 Equus caballus ENSECAG00000009866 N 0.942
GRHL3 Microcebus murinus ENSMICG00000000542 N 0.939
ENSMLUG00000012056 Myotis lucifugus ENSMLUG00000012056 N 0.934
GRHL3 Oryctolagus cuniculus ENSOCUG00000013357 N 0.934
GRHL3 Pteropus vampyrus ENSPVAG00000005827 N 0.934
ENSMPUG00000015840 Mustela putorius furo ENSMPUG00000015840 N 0.934
GRHL3 Otolemur garnettii ENSOGAG00000011027 N 0.934
GRHL3 Procavia capensis ENSPCAG00000011355 N 0.933
ENSBTAP00000026370-D1 Bos grunniens ENSBTAP00000026370-D1 N 0.933
GRHL3 Bos taurus ENSBTAG00000019791 N 0.933
GRHL3 Canis familiaris ENSCAFG00000012994 N 0.929
GRHL3 Callithrix jacchus ENSCJAG00000020858 N 0.929
GRHL3 Choloepus hoffmanni ENSCHOG00000000305 N 0.929
ENSSTOG00000023529 Ictidomys tridecemlineatus ENSSTOG00000023529 N 0.927
GRHL3 Echinops telfairi ENSETEG00000001594 N 0.927
GRHL3 Dasypus novemcinctus ENSDNOG00000013939 N 0.924
GRHL3 Tursiops truncatus ENSTTRG00000016160 N 0.924
GRHL3 Loxodonta africana ENSLAFG00000001618 N 0.924
ENSMLUG00000027396 Myotis lucifugus ENSMLUG00000027396 N 0.922
GRHL3 Ochotona princeps ENSOPRG00000003928 N 0.920
GRHL3 Cavia porcellus ENSCPOG00000008841 N 0.919
ENSMEUG00000004978 Macropus eugenii ENSMEUG00000004978 N 0.884
ENSOARG00000006636 Ovis aries ENSOARG00000006636 N 0.881
GRHL3 Sus scrofa ENSSSCG00000003539 N 0.878
GRHL3 Monodelphis domestica ENSMODG00000013064 N 0.874
Grhl3 Rattus norvegicus ENSRNOG00000029427 N 0.871
GRHL3 Felis catus ENSFCAG00000019048 N 0.866
ENSAMEG00000009982 Ailuropoda melanoleuca ENSAMEG00000009982 N 0.861
GRHL3 Macaca mulatta ENSMMUG00000004463 N 0.853
ENSSHAG00000008311 Sarcophilus harrisii ENSSHAG00000008311 N 0.852
GRHL3 Anolis carolinensis ENSACAG00000017262 N 0.836
Cmyd_10004499 Chelonia mydas Cmyd_10004499 N 0.796
ENSNLEG00000008898 Nomascus leucogenys ENSNLEG00000008898 N 0.794
Alligator_sinensis_CCG010998.1 Alligator sinensis Alligator_sinensis_CCG010998.1 N 0.786
GRHL3 Taeniopygia guttata ENSTGUG00000001153 N 0.785
Gfo_R011603 Geospiza fortis Gfo_R011603 N 0.782
ENSPSIG00000016215 Pelodiscus sinensis ENSPSIG00000016215 N 0.782
Tal_R005479 Tyto alba Tal_R005479 N 0.777
ENSAPLG00000003161 Anas platyrhynchos ENSAPLG00000003161 N 0.777
GRHL3 Gallus gallus ENSGALG00000004249 N 0.777
Afo_R008962 Aptenodytes forsteri Afo_R008962 N 0.777
ENSFALG00000000490 Ficedula albicollis ENSFALG00000000490 N 0.776
Brh_R012570 Buceros rhinoceros Brh_R012570 N 0.773
Aan_R005902 Calypte anna Aan_R005902 N 0.773
Pvit_10773 Pogona vitticeps Pvit_10773 N 0.768
GRHL3 Meleagris gallopavo ENSMGAG00000005903 N 0.761
GRHL3 Ornithorhynchus anatinus ENSOANG00000002207 N 0.753
ENSONIG00000003513 Oreochromis niloticus ENSONIG00000003513 N 0.724
grhl3.L Xenopus laevis XB-GENE-919808 N 0.723
grhl3.S Xenopus laevis XB-GENE-17342846 N 0.722
grhl3 Xenopus tropicalis XB-GENE-919797 N 0.718
ENSSTOG00000019842 Ictidomys tridecemlineatus ENSSTOG00000019842 I 0.716
grhl1 Danio rerio ENSDARG00000061391 I 0.714
ENSGMOG00000002256 Gadus morhua ENSGMOG00000002256 N 0.700