SIX4 (Choloepus hoffmanni)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSCHOG00000005951 T207766_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Six4
M00461_2.00
Mus musculus
NNKABMHNN

NNDKVTMNN
PBM
Berger et al.(2008)
Six4_2860
0.821 0.962
SIX4
M04939_2.00
Homo sapiens
NVYGATACVB

VBGTATCRBN
SELEX
Yin et al.(2017)
SIX4_eDBD_HT-SELEX
0.821 0.962
Six4
M09198_2.00
Mus musculus
DGDAABHNSASNNN

NNNSTSNDVTTHCH
Misc
Kulakovskiy et al.(2013)
SIX4_MOUSE.H11MO.0.C
0.821 0.962
SIX4
M10646_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SIX4_Q3
0.821 0.962
SIX4
M04940_2.00
Homo sapiens
NBGTAWCRHN

NDYGWTACVN
SELEX
Yin et al.(2017)
SIX4_eDBD_Methyl-HT-SELEX
0.821 0.962
Six4
M00563_2.00
Drosophila melanogaster
NNDANMHNN

NNDKNTHNN
PBM
Busser et al.(2012a)
Six4
0.794 0.769
Six4
M06530_2.00
Drosophila melanogaster
TGABAC

GTVTCA
B1H
Mathelier et al.(2014)
MA0204.1
0.794 0.769
Six4
M06334_2.00
Drosophila melanogaster
WDDTGABAC

GTVTCAHHW
B1H
Zhu et al.(2011)
Six4_Cell_FBgn0027364
0.794 0.769
Six4
M06335_2.00
Drosophila melanogaster
NTGAKACB

VGTMTCAN
B1H
Zhu et al.(2011)
Six4_SOLEXA_2_FBgn0027364
0.794 0.769
Six4
M06336_2.00
Drosophila melanogaster
NNNTGABA

TVTCANNN
B1H
Zhu et al.(2011)
Six4_SOLEXA_FBgn0027364
0.794 0.769
SIX5
M08208_2.00
Homo sapiens
GARWTGTAGT

ACTACAWYTC
ChIP-seq
Contrino et al.(2012)
Mv121
0.793 0.750
SIX5
M08209_2.00
Homo sapiens
GGAGTTGT

ACAACTCC
ChIP-seq
Contrino et al.(2012)
Mv123
0.793 0.750
SIX5
M10738_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SIX5_01
0.793 0.750
SIX5
M10739_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SIX5_02
0.793 0.750
Six2
M00425_2.00
Mus musculus
NNAYMYNN

NNRKRTNN
PBM
Berger et al.(2008)
Six2_2307
0.674 0.712
Six1
M00512_2.00
Mus musculus
NNDATMYNNN

NNNRKATHNN
PBM
Berger et al.(2008)
Six1_0935
0.674 0.712
SIX1
M05094_2.00
Homo sapiens
NNYGATACVB

VBGTATCRNN
SELEX
Yin et al.(2017)
SIX1_eDBD_HT-SELEX
0.674 0.712
SIX1
M05096_2.00
Homo sapiens
NNYGATAYVB

VBRTATCRNN
SELEX
Yin et al.(2017)
SIX1_FL_HT-SELEX
0.674 0.712
SIX2
M05285_2.00
Homo sapiens
NNYGATACSB

VSGTATCRNN
SELEX
Yin et al.(2017)
SIX2_eDBD_HT-SELEX
0.674 0.712
SIX2
M05287_2.00
Homo sapiens
NSGTRWCRYN

NRYGWYACSN
SELEX
Yin et al.(2017)
SIX2_FL_HT-SELEX
0.674 0.712
SIX1
M08130_2.00
Homo sapiens
GWAACCTGANM

KNTCAGGTTWC
ChIP-seq
Mathelier et al.(2014)
MA1118.1
0.674 0.712
SIX2
M08133_2.00
Homo sapiens
NNNTGWAACCTGAKMH

DKMTCAGGTTWCANNN
ChIP-seq
Mathelier et al.(2014)
MA1119.1
0.674 0.712
SIX1
M09142_2.00
Homo sapiens
DGWAAYHTGABMYN

NRKVTCADRTTWCH
Misc
Kulakovskiy et al.(2013)
SIX1_HUMAN.H11MO.0.A
0.674 0.712
SIX2
M09157_2.00
Homo sapiens
DGWAAYHHGABMH

DKVTCDDRTTWCH
Misc
Kulakovskiy et al.(2013)
SIX2_HUMAN.H11MO.0.A
0.674 0.712
Six2
M09185_2.00
Mus musculus
DGWAAYHYRABMYB

VRKVTYRDRTTWCH
Misc
Kulakovskiy et al.(2013)
SIX2_MOUSE.H11MO.0.A
0.674 0.712
Six1
M09579_2.00
Mus musculus
GWAAYHTGABMH

DKVTCADRTTWC
Misc
Heinz et al.(2010)
Myoblast-Six1_GSE20150
0.674 0.712
SIX1
M10684_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SIX1_Q3_01
0.674 0.712
SIX1
M10685_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SIX1_Q3
0.674 0.712
SIX1
M05095_2.00
Homo sapiens
NNYGATABNB

VNVTATCRNN
SELEX
Yin et al.(2017)
SIX1_eDBD_Methyl-HT-SELEX
0.674 0.712
SIX1
M05097_2.00
Homo sapiens
NNYGATAYSB

VSRTATCRNN
SELEX
Yin et al.(2017)
SIX1_FL_Methyl-HT-SELEX
0.674 0.712
SIX2
M05286_2.00
Homo sapiens
NBRTATCRNN

NNYGATAYVN
SELEX
Yin et al.(2017)
SIX2_eDBD_Methyl-HT-SELEX
0.674 0.712
SIX2
M05288_2.00
Homo sapiens
VBRTAWCRNN

NNYGWTAYVB
SELEX
Yin et al.(2017)
SIX2_FL_Methyl-HT-SELEX
0.674 0.712
so
M02117_2.00
Drosophila melanogaster
NDATMYNNN

NNNRKATHN
PBM
Weirauch et al.(2014)
pTH5690
0.674 0.692
so
M03800_2.00
Drosophila melanogaster
NYGATAYB

VRTATCRN
SELEX
Nitta et al.(2015)
so_1
0.674 0.692
so
M03801_2.00
Drosophila melanogaster
YKATAYNNNYGATAY

RTATCRNNNRTATMR
SELEX
Nitta et al.(2015)
so_2
0.674 0.692
so
M03802_2.00
Drosophila melanogaster
YGATACGTATCR

YGATACGTATCR
SELEX
Nitta et al.(2015)
so_3
0.674 0.692
so
M03803_2.00
Drosophila melanogaster
RTATCRYGATAC

GTATCRYGATAY
SELEX
Nitta et al.(2015)
so_4
0.674 0.692
so
M06497_2.00
Drosophila melanogaster
TGATAC

GTATCA
B1H
Mathelier et al.(2014)
MA0246.1
0.674 0.692
so
M06268_2.00
Drosophila melanogaster
NRTGATA

TATCAYN
B1H
Zhu et al.(2011)
So_Cell_FBgn0003460
0.674 0.692
so
M06269_2.00
Drosophila melanogaster
NNNTGATA

TATCANNN
B1H
Zhu et al.(2011)
So_SOLEXA_FBgn0003460
0.674 0.692
ceh-34
M00672_2.00
Caenorhabditis elegans
NNNRDAWNNN

NNNWTHYNNN
PBM
Narasimhan et al.(2015)
pTH9708
0.601 0.577
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSCHOP00000005263 Homeodomain 220 271

Links

Other Homeodomain family TFs
Other Choloepus hoffmanni TFs

536 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ACRE_013920 Acremonium chrysogenum ACRE_013920 I 0.000
AB05039.1 Alternaria brassicicola AB05039.1 I 0.000
AOL_s00083g376 Arthrobotrys oligospora AOL_s00083g376 I 0.000
AOL_s00176g84 Arthrobotrys oligospora AOL_s00176g84 I 0.000
ARB_00054 Arthroderma benhamiae ARB_00054 I 0.000
MCYG_00396 Arthroderma otae MCYG_00396 I 0.000
e_gw1.00141.1.1 Aspergillus carbonarius e_gw1.00141.1.1 I 0.000
ACLA_019870 Aspergillus clavatus CADACLAG00002121 I 0.000
CADAFLAG00001174 Aspergillus flavus CADAFLAG00001174 I 0.000
AFUA_1G15470 Aspergillus fumigatus CADAFUAG00006845 I 0.000
ANIA_00891 Aspergillus nidulans CADANIAG00001766 D 0.000
CADANGAG00001387 Aspergillus niger CADANGAG00001387 I 0.000
CADAORAG00003061 Aspergillus oryzae CADAORAG00003061 I 0.000
EURHEDRAFT_512269 Aspergillus ruber EURHEDRAFT_512269 I 0.000
ATEG_05241 Aspergillus terreus CADATEAG00005466 I 0.000
M437DRAFT_57418 Aureobasidium melanogenum M437DRAFT_57418 I 0.000
M438DRAFT_363096 Aureobasidium pullulans M438DRAFT_363096 I 0.000
AUEXF2481DRAFT_37011 Aureobasidium subglaciale AUEXF2481DRAFT_37011 I 0.000
BBA_01502 Beauveria bassiana BBA_01502 I 0.000
COCC4DRAFT_164616 Bipolaris maydis COCC4DRAFT_164616 I 0.000
COCMIDRAFT_37182 Bipolaris oryzae COCMIDRAFT_37182 I 0.000
COCSADRAFT_33134 Bipolaris sorokiniana COCSADRAFT_33134 I 0.000
COCVIDRAFT_36967 Bipolaris victoriae COCVIDRAFT_36967 I 0.000
COCCADRAFT_91527 Bipolaris zeicola COCCADRAFT_91527 I 0.000
BDDG_02937 Blastomyces dermatitidis BDDG_02937 I 0.000
Bcin06g05430 Botrytis cinerea Bcin06g05430 I 0.000
PVAR5_6826 Byssochlamys spectabilis PVAR5_6826 I 0.000
A1O1_04627 Capronia coronata A1O1_04627 I 0.000
A1O3_06762 Capronia epimyces A1O3_06762 I 0.000
PV04_08241 Capronia semiimmersa PV04_08241 I 0.000
CHGG_04684 Chaetomium globosum CHGG_04684 I 0.000
CTHT_0033150 Chaetomium thermophilum CTHT_0033150 I 0.000
Z519_05285 Cladophialophora bantiana Z519_05285 I 0.000
G647_02322 Cladophialophora carrionii G647_02322 I 0.000
PV07_11989 Cladophialophora immunda PV07_11989 I 0.000
A1O5_09172 Cladophialophora psammophila A1O5_09172 I 0.000
A1O7_07756 Cladophialophora yegresii A1O7_07756 I 0.000
estExt_Genewise1Plus.C_110260 Cochliobolus heterostrophus C5 estExt_Genewise1Plus.C_110260 I 0.000
CFIO01_05405 Colletotrichum fioriniae CFIO01_05405 I 0.000
GLRG_02905 Colletotrichum graminicola GLRG_02905 I 0.000
CH063_00339 Colletotrichum higginsianum CH063_00339 I 0.000
Cob_10644 Colletotrichum orbiculare Cob_10644 I 0.000
CSUB01_03445 Colletotrichum sublineola CSUB01_03445 I 0.000
estExt_fgenesh1_pm.C_30857 Cryphonectria parasitica estExt_fgenesh1_pm.C_30857 I 0.000
HMPREF1541_02980 Cyphellophora europaea HMPREF1541_02980 I 0.000
H072_8968 Dactylellina haptotyla H072_8968 I 0.000
H072_536 Dactylellina haptotyla H072_536 I 0.000
DOTSEDRAFT_168469 Dothistroma septosporum DOTSEDRAFT_168469 I 0.000
DRE_04634 Drechslerella stenobrocha DRE_04634 I 0.000
DRE_04272 Drechslerella stenobrocha DRE_04272 I 0.000
A1O9_01921 Exophiala aquamarina A1O9_01921 I 0.000
HMPREF1120_01697 Exophiala dermatitidis HMPREF1120_01697 I 0.000
PV10_02852 Exophiala mesophila PV10_02852 I 0.000
PV06_02197 Exophiala oligosperma PV06_02197 I 0.000
PV11_06636 Exophiala sideris PV11_06636 I 0.000
PV08_11504 Exophiala spinifera PV08_11504 I 0.000
PV05_08638 Exophiala xenobiotica PV05_08638 I 0.000
Z517_03416 Fonsecaea pedrosoi Z517_03416 I 0.000
FFUJ_05000 Fusarium fujikuroi FFUJ_05000 I 0.000
FGRRES_05120 Fusarium graminearum FGRRES_05120 I 0.000
FOXG_08561 Fusarium oxysporum FOXG_08561 I 0.000
FPSE_06516 Fusarium pseudograminearum FPSE_06516 I 0.000
NechaG34259 Fusarium solani NechaG34259 I 0.000
FVEG_06107 Fusarium verticillioides FVEG_06107 I 0.000
GGTG_08486 Gaeumannomyces graminis GGTG_08486 I 0.000
CMQ_4539 Grosmannia clavigera CMQ_4539 I 0.000
LEMA_P071070.1 Leptosphaeria maculans LEMA_P071070.1 I 0.000
MPH_07179 Macrophomina phaseolina MPH_07179 I 0.000
MGG_01486 Magnaporthe oryzae MGG_01486 I 0.000
MAC_00713 Metarhizium acridum MAC_00713 I 0.000
MAM_03896 Metarhizium album MAM_03896 I 0.000
MANI_017491 Metarhizium anisopliae MANI_017491 I 0.000
MANI_020514 Metarhizium anisopliae MANI_020514 I 0.000
MBR_00363 Metarhizium brunneum MBR_00363 I 0.000
MBR_10129 Metarhizium brunneum MBR_10129 I 0.000
MGU_01179 Metarhizium guizhouense MGU_01179 I 0.000
MGU_01344 Metarhizium guizhouense MGU_01344 I 0.000
MAJ_01729 Metarhizium majus MAJ_01729 I 0.000
MAJ_05413 Metarhizium majus MAJ_05413 I 0.000
X797_005320 Metarhizium robertsii X797_005320 I 0.000
X797_008631 Metarhizium robertsii X797_008631 I 0.000
MCYG_00396 Microsporum canis MCYG_00396 I 0.000
MGYG_01563 Microsporum gypseum MGYG_01563 I 0.000
MYCTH_73877 Myceliophthora thermophila MYCTH_73877 I 0.000
e_gw1.13.532.1 Mycosphaerella fijiensis e_gw1.13.532.1 I 0.000
e_gw1.1.122.1 Mycosphaerella graminicola e_gw1.1.122.1 I 0.000
e_gw1.18.749.1 Nectria haematococca e_gw1.18.749.1 I 0.000
UCRNP2_2538 Neofusicoccum parvum UCRNP2_2538 I 0.000
NFIA_009930 Neosartorya fischeri CADNFIAG00000876 I 0.000
pco-1 Neurospora crassa NCU07669 I 0.000
estExt_fgenesh2_pg.C_30542 Neurospora discreta estExt_fgenesh2_pg.C_30542 I 0.000
OIDMADRAFT_175432 Oidiodendron maius OIDMADRAFT_175432 I 0.000
F503_04272 Ophiostoma piceae uamh F503_04272 I 0.000
PAAG_02168 Paracoccidioides sp lutzii PAAG_02168 I 0.000
Pc06g01740 Penicillium chrysogenum Pc06g01740 I 0.000
Pc20g07370 Penicillium chrysogenum Pc20g07370 I 0.000
PDIP_65300 Penicillium digitatum PDIP_65300 I 0.000
PDIP_00450 Penicillium digitatum PDIP_00450 I 0.000
PEX1_016570 Penicillium expansum PEX1_016570 I 0.000
PEX1_052640 Penicillium expansum PEX1_052640 I 0.000
PITC_063170 Penicillium italicum PITC_063170 I 0.000
PITC_097400 Penicillium italicum PITC_097400 I 0.000
PMAA_074650 Penicillium marneffei PMAA_074650 I 0.000
PDE_00471 Penicillium oxalicum PDE_00471 I 0.000
PCH_Pc20g07370 Penicillium rubens PCH_Pc20g07370 I 0.000
PCH_Pc06g01740 Penicillium rubens PCH_Pc06g01740 I 0.000
U727_0043044011 Penicillium solitum U727_0043044011 I 0.000
U727_0043077061 Penicillium solitum U727_0043077061 I 0.000
PFICI_04606 Pestalotiopsis fici PFICI_04606 I 0.000
SNOG_06526 Phaeosphaeria nodorum SNOG_06526 I 0.000
PODANS_6_3420 Podospora anserina PODANS_6_3420 I 0.000
MYCFIDRAFT_105751 Pseudocercospora fijiensis MYCFIDRAFT_105751 I 0.000
GMDG_01454 Pseudogymnoascus destructans GMDG_01454 I 0.000
V499_02941 Pseudogymnoascus pannorum V499_02941 I 0.000
PTT_10835 Pyrenophora teres PTT_10835 I 0.000
PTRG_02401 Pyrenophora triticirepentis PTRG_02401 I 0.000
Z518_06680 Rhinocladiella mackenziei Z518_06680 I 0.000
SBOR_0009 Sclerotinia borealis SBOR_0009 I 0.000
SS1G_02930 Sclerotinia sclerotiorum SS1G_02930 I 0.000
SETTUDRAFT_86552 Setosphaeria turcica SETTUDRAFT_86552 I 0.000
SMAC_00882 Sordaria macrospora SMAC_00882 I 0.000
SEPMUDRAFT_148320 Sphaerulina musiva SEPMUDRAFT_148320 I 0.000
SPBR_00103 Sporothrix brasiliensis SPBR_00103 I 0.000
HMPREF1624_05877 Sporothrix schenckii HMPREF1624_05877 I 0.000
S40288_06219 Stachybotrys chartarum S40288_06219 I 0.000
S40285_00991 Stachybotrys chlorohalonata S40285_00991 I 0.000
SNOG_06526 Stagonospora nodorum SNOG_06526 I 0.000
PMAA_074650 Talaromyces marneffei PMAA_074650 I 0.000
TSTA_095240 Talaromyces stipitatus TSTA_095240 I 0.000
THITE_2045084 Thielavia terrestris THITE_2045084 I 0.000
UCRPA7_486 Togninia minima UCRPA7_486 I 0.000
VHEMI03524 Torrubiella hemipterigena VHEMI03524 I 0.000
TRIATDRAFT_172139 Trichoderma atroviride TRIATDRAFT_172139 I 0.000
TRIREDRAFT_35454 Trichoderma reesei TRIREDRAFT_35454 I 0.000
TRIVIDRAFT_54183 Trichoderma virens TRIVIDRAFT_54183 I 0.000
TEQG_03625 Trichophyton equinum TEQG_03625 I 0.000
H101_05531 Trichophyton interdigitale H101_05531 I 0.000
H102_00998 Trichophyton rubrum H102_00998 I 0.000
H105_01004 Trichophyton soudanense H105_01004 I 0.000
TESG_06519 Trichophyton tonsurans TESG_06519 I 0.000
GSTUM_00006643001 Tuber melanosporum GSTUM_00006643001 I 0.000
GSTUM_00005791001 Tuber melanosporum GSTUM_00005791001 I 0.000
UREG_07163 Uncinocarpus reesii UREG_07163 I 0.000
UV8b_2167 Ustilaginoidea virens UV8b_2167 I 0.000
PV09_01829 Verruconis gallopava PV09_01829 I 0.000
VDBG_01044 Verticillium albo atrum VDBG_01044 I 0.000
VDBG_01044 Verticillium alfalfae VDBG_01044 I 0.000
VDAG_00659 Verticillium dahliae VDAG_00659 I 0.000
Mycgr3G31719 Zymoseptoria tritici Mycgr3G31719 I 0.000