irx-1 (Caenorhabditis elegans)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 WBGene00007984 T224653_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell development; neuron differentiation; and regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in head muscle; hypodermis; intestine; neurons; and somatic nervous system. Orthologous to several human genes including IRX5 (iroquois homeobox 5). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
CBG08197
M02064_2.00 		Caenorhabditis briggsae
NNDACDNN
NNHGTHNN		 PBM
Weirauch et al.(2014)
pTH6408 		0.834 0.964
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
C36F7.1 Homeodomain 118 175

Links

Other Homeodomain family TFs
Other Caenorhabditis elegans TFs

31 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CBG08197 Caenorhabditis briggsae CBG08197 D 0.834
CRE09644 Caenorhabditis remanei CRE09644 I 0.822
CJA00344 Caenorhabditis japonica CJA00344 I 0.820
CBN07279 Caenorhabditis brenneri CBN07279 I 0.820
CBN12980 Caenorhabditis brenneri CBN12980 I 0.820
SNAPOd2T00027338001 Oikopleura dioica SNAPOd2T00027338001 I 0.724
e_gw.97.193.1 Branchiostoma floridae e_gw.97.193.1 I 0.690
csin108827 Clonorchis sinensis csin108827 I 0.683
Sjc_0031820 Schistosoma japonicum Sjc_0031820 I 0.678
Smp_149230 Schistosoma mansoni Smp_149230 I 0.678
Sjc_0031830 Schistosoma japonicum Sjc_0031830 I 0.678
csin107852 Clonorchis sinensis csin107852 I 0.675
HNAJ_0000146901 Hymenolepis nana HNAJ_0000146901 I 0.675
TsM_000262600 Taenia solium TsM_000262600 I 0.675
TTAC_0000065401 Hydatigera taeniaeformis TTAC_0000065401 I 0.675
TASK_0000023001 Taenia asiatica TASK_0000023001 I 0.675
T265_13435 Opisthorchis viverrini T265_13435 I 0.675
HmN_000708300 Hymenolepis microstoma HmN_000708300 I 0.675
ECANG7_08640 Echinococcus canadensis ECANG7_08640 I 0.675
Cmyd_10004597 Chelonia mydas Cmyd_10004597 I 0.636
HDID_0000302701 Hymenolepis diminuta HDID_0000302701 I 0.635
HmN_000469000 Hymenolepis microstoma HmN_000469000 I 0.635
gw.90.185.1 Branchiostoma floridae gw.90.185.1 I 0.619
Ppa-irx-1 Pristionchus pacificus PPA16597 I 0.609
HelroG127856 Helobdella robusta HelroG127856 I 0.607
irx1.L Xenopus laevis XB-GENE-865648 I 0.607
Aan_R002774 Calypte anna Aan_R002774 I 0.607
Gfo_R006171 Geospiza fortis Gfo_R006171 I 0.607
Brh_R009856 Buceros rhinoceros Brh_R009856 I 0.607
ENSGMOG00000011698 Gadus morhua ENSGMOG00000011698 I 0.605
HelroG153627 Helobdella robusta HelroG153627 I 0.603