MATALPHA2 (Saccharomyces cerevisiae)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 YCR039C T224756_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA binding activity, bending; DNA-binding transcription repressor activity, RNA polymerase II-specific; and sequence-specific DNA binding activity. Involved in negative regulation of mating-type specific transcription from RNA polymerase II promoter. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
MATALPHA2
M01550_2.00		 Saccharomyces cerevisiae
NDNACAAT
ATTGTNHN		 PBM
Zhu et al.(2009)
Matalpha2		 (Direct) (Direct)
MATALPHA2
M02189_2.00		 Saccharomyces cerevisiae
NNNDCDNN
NNHGHNNN		 PBM
Weirauch et al.(2014)
pTH6506		 (Direct) (Direct)
MATALPHA2
M08570_2.00		 Saccharomyces cerevisiae
ACAYGH
DCRTGT		 Misc
DeBoer et al.(2011)
YCR039C_1364		 (Direct) (Direct)
MATALPHA2
M10791_2.00		 Saccharomyces cerevisiae
DWNNACAYGN
NCRTGTNNWH		 Transfac
Matys et al.(2006)
F$MATALPHA2_01		 (Direct) (Direct)
MATALPHA2
M10792_2.00		 Saccharomyces cerevisiae Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
F$MATALPHA2_08		 (Direct) (Direct)
MATALPHA2
M10793_2.00		 Saccharomyces cerevisiae Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
F$MATALPHA2P_Q4		 (Direct) (Direct)
MATALPHA2
M10794_2.00		 Saccharomyces cerevisiae Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
F$MATALPHA2_Q4		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
HMLALPHA2
M00915_2.00 		Saccharomyces cerevisiae
NNDACRHN
NDYGTHNN		 PBM
Gordan et al.(2011)
Hmlalpha2 		0.867 1.000
HMRA2
M00055_2.00 		Saccharomyces cerevisiae
CRTGTAAW
WTTACAYG		 PBM
Badis et al.(2008)
HMRA2_2071 		0.867 1.000
HMRA2
M07484_2.00 		Saccharomyces cerevisiae
YRTGTAAW
WTTACAYR		 PBM, CSA and or DIP-chip
Mathelier et al.(2014)
MA0318.1 		0.867 1.000
HMRA2
M08571_2.00 		Saccharomyces cerevisiae
YRTGTAAW
WTTACAYR		 Misc
DeBoer et al.(2011)
YCR096C_558 		0.867 1.000
MTAL2_KLUDE
M02197_2.00 		Kluyveromyces delphensis
CRTGTAWW
WWTACAYG		 PBM
Weirauch et al.(2014)
pTH5974 		0.736 0.679
For this family, TFs with SR scores > 0.599 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M01550_2.00 Homeodomain 131 189
M02189_2.00 Homeodomain 1 58

DNA Binding Domains

Protein ID Domain From To Sequence
YCR039C Homeodomain 131 189

Links

Other Homeodomain family TFs
Other Saccharomyces cerevisiae TFs

Invalid Input OrderBy

24 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action