POU4F2 (Homo sapiens)
Homeodomain,POU

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox)
PF00157 (Pou)
IPR001356
IPR000327
ENSG00000151615 T238194_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
The protein encoded by this gene is a member of the POU-domain transcription factor family and may be involved in maintaining visual system neurons in the retina. The level of the encoded protein is also elevated in a majority of breast cancers, resulting in accelerated tumor growth. [provided by RefSeq, Sep 2011]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
POU4F2
M03310_2.00
Homo sapiens
BTMATTAAWTATKCAN

NTGMATAWTTAATKAV
SELEX
Jolma et al.(2013)
POU4F2_1
(Direct) (Direct)
POU4F2
M03311_2.00
Homo sapiens
BTMATTAATTATKCAN

NTGMATAATTAATKAV
SELEX
Jolma et al.(2013)
POU4F2_2
(Direct) (Direct)
POU4F2
M10839_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$BRN3B_Q2
(Direct) (Direct)
POU4F2
M10840_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$POU4F2_02
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.993 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000281321 POU 253 327
ENSP00000281321 Homeodomain 346 402

Links

Other Homeodomain,POU family TFs
Other Homo sapiens TFs

47 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
POU4F2 Pteropus vampyrus ENSPVAG00000011688 I 1.000
Pou4f2 Rattus norvegicus ENSRNOG00000012167 I 1.000
POU4F2 Sorex araneus ENSSARG00000007463 I 1.000
ENSSHAG00000013709 Sarcophilus harrisii ENSSHAG00000013709 I 1.000
POU4F2 Pan troglodytes ENSPTRG00000016492 I 1.000
ENSPSIG00000001736 Pelodiscus sinensis ENSPSIG00000001736 I 1.000
POU4F2 Ochotona princeps ENSOPRG00000011220 I 1.000
ENSPANG00000006551 Papio anubis ENSPANG00000006551 I 1.000
POU4F2 Procavia capensis ENSPCAG00000002636 I 1.000
ENSPPYG00000015107 Pongo abelii ENSPPYG00000015107 I 1.000
ENSSSCG00000009034 Sus scrofa ENSSSCG00000009034 I 1.000
POU4F2 Sus scrofa ENSSSCG00000026015 I 1.000
Myotis_brandtii_POU4F2_10016901 Myotis brandtii Myotis_brandtii_POU4F2_10016901 I 1.000
Ogr03813 Ophisaurus gracilis Ogr03813 I 1.000
Pvit_02490 Pogona vitticeps Pvit_02490 I 1.000
pou4f2 Xenopus tropicalis XB-GENE-854899 I 1.000
ENSP00000281321 Macaca fascicularis ENSP00000281321 I 1.000
ENSP00000281321-D1 Bos grunniens ENSP00000281321-D1 I 1.000
ENSSTOG00000021113 Ictidomys tridecemlineatus ENSSTOG00000021113 I 1.000
POU4F2 Vicugna pacos ENSVPAG00000006925 I 1.000
Alligator_sinensis_CCG006380.1 Alligator sinensis Alligator_sinensis_CCG006380.1 I 1.000
Cmyd_10009510 Chelonia mydas Cmyd_10009510 I 1.000
POU4F2 Otolemur garnettii ENSOGAG00000028626 I 1.000
POU4F2 Ornithorhynchus anatinus ENSOANG00000006897 I 1.000
Pou4f2 Dipodomys ordii ENSDORG00000004448 I 1.000
POU4F2 Equus caballus ENSECAG00000020754 I 1.000
POU4F2 Felis catus ENSFCAG00000003049 I 1.000
POU4F2 Gorilla gorilla ENSGGOG00000001836 I 1.000
POU4F2 Dasypus novemcinctus ENSDNOG00000013134 I 1.000
ENSCSAG00000003411 Chlorocebus sabaeus ENSCSAG00000003411 I 1.000
POU4F2 Bos taurus ENSBTAG00000005648 I 1.000
POU4F2 Canis familiaris ENSCAFG00000007756 I 1.000
POU4F2 Callithrix jacchus ENSCJAG00000002462 I 1.000
POU4F2 Cavia porcellus ENSCPOG00000013770 I 1.000
ENSGMOG00000000453 Gadus morhua ENSGMOG00000000453 I 1.000
ENSLACG00000005883 Latimeria chalumnae ENSLACG00000005883 I 1.000
POU4F2 Monodelphis domestica ENSMODG00000000557 I 1.000
ENSMPUG00000006963 Mustela putorius furo ENSMPUG00000006963 I 1.000
Pou4f2 Mus musculus ENSMUSG00000031688 I 1.000
ENSNLEG00000005619 Nomascus leucogenys ENSNLEG00000005619 I 1.000
POU4F2 Macaca mulatta ENSMMUG00000023440 I 1.000
POU4F2 Myotis lucifugus ENSMLUG00000015174 I 1.000
POU4F2 Loxodonta africana ENSLAFG00000001505 I 1.000
ENSLOCG00000008825 Lepisosteus oculatus ENSLOCG00000008825 I 1.000
ENSMEUG00000012973 Macropus eugenii ENSMEUG00000012973 I 1.000
ENSMICG00000000575 Microcebus murinus ENSMICG00000000575 I 1.000
ENSAMEG00000016679 Ailuropoda melanoleuca ENSAMEG00000016679 I 1.000