HHAL000384-PA (Halyomorpha halys)
HSF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00447 (HSF_DNA-bind) IPR000232 HHAL000384-PA T243446_2.00 Misc (2018-Jan-19)
NCBI Gene Info:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Hsf
M03908_2.00
Drosophila melanogaster
BVGAANRTTCTVGAANN

NNTTCBAGAAYNTTCBV
SELEX
Nitta et al.(2015)
Hsf_1
0.323 0.594
Hsf
M03909_2.00
Drosophila melanogaster
NVGAAYNTTCBAGAANN

NNTTCTVGAANRTTCBN
SELEX
Nitta et al.(2015)
Hsf_2
0.323 0.594
Hsf
M03910_2.00
Drosophila melanogaster
NVGAAYNTTCTVGAANN

NNTTCBAGAANRTTCBN
SELEX
Nitta et al.(2015)
Hsf_3
0.323 0.594
Hsf
M03911_2.00
Drosophila melanogaster
NVGAANRTTCBAGAANN

NNTTCTVGAAYNTTCBN
SELEX
Nitta et al.(2015)
Hsf_4
0.323 0.594
Hsf
M06388_2.00
Drosophila melanogaster
KMGAADNTTCKMGA

TCKMGAANHTTCKM
B1H
Zhu et al.(2011)
Hsf_FlyReg_FBgn0001222
0.323 0.594
Hsf
M10869_2.00
Drosophila melanogaster
HTTCK

MGAAD
Transfac
Matys et al.(2006)
I$HSF_01
0.323 0.594
Hsf
M10870_2.00
Drosophila melanogaster
MGAADMGAADMGAAD

HTTCKHTTCKHTTCK
Transfac
Matys et al.(2006)
I$HSF_02
0.323 0.594
Hsf
M10871_2.00
Drosophila melanogaster
MGAADHTTCKHTTCK

MGAADMGAADHTTCK
Transfac
Matys et al.(2006)
I$HSF_03
0.323 0.594
Hsf
M10872_2.00
Drosophila melanogaster
MGAADHTTCKMGAAD

HTTCKMGAADHTTCK
Transfac
Matys et al.(2006)
I$HSF_04
0.323 0.594
Hsf
M10873_2.00
Drosophila melanogaster
HTTCKHTTCKMGAAD

HTTCKMGAADMGAAD
Transfac
Matys et al.(2006)
I$HSF_05
0.323 0.594
For this family, TFs with SR scores > 0.318 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
HHAL000384-PA HSF 13 114

Links

Other HSF family TFs
Other Halyomorpha halys TFs

21 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ACOM023042 Anopheles coluzzii ACOM023042 I 0.343
ACHR001316 Anopheles christyi ACHR001316 I 0.343
AATE001173 Anopheles atroparvus AATE001173 I 0.343
AAEL010319 Aedes aegypti AAEL010319 I 0.343
AFAF007194 Anopheles farauti AFAF007194 I 0.343
AFUN004137 Anopheles funestus AFUN004137 I 0.343
AGAP011082 Anopheles gambiae AGAP011082 I 0.343
AMIN008510 Anopheles minimus AMIN008510 I 0.343
AMEC006872 Anopheles melas AMEC006872 I 0.343
MDOA007596 Musca domestica MDOA007596 I 0.342
LCUP016473 Lucilia cuprina LCUP016473 I 0.342
17549 Aureococcus anophagefferens 17549 N 0.333
CLEC004858 Cimex lectularius CLEC004858 I 0.332
DAPPUDRAFT_213340 Daphnia pulex DAPPUDRAFT_213340 I 0.328
GF12282 Drosophila ananassae FBgn0089319 I 0.324
Hsf Drosophila melanogaster FBgn0001222 D 0.323
GG20992 Drosophila erecta FBgn0113176 I 0.323
Hsf Drosophila yakuba FBgn0066133 I 0.323
GM19926 Drosophila sechellia FBgn0174812 I 0.323
ACEP13468 Atta cephalotes ACEP13468 I 0.321
THOM_0075 Trachipleistophora hominis THOM_0075 N 0.319