irf2a (Danio rerio)
IRF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00605 (IRF) IPR001346 ENSDARG00000007387 T244010_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in immune system process and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within cell population proliferation and regulation of transcription, DNA-templated. Predicted to be active in nucleus. Orthologous to human IRF2 (interferon regulatory factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Irf2
M00805_2.00 		Mus musculus
NDWNHGAAAV
BTTTCDNWHN		 PBM
Weirauch et al.(2013)
pTH2835 		0.867 0.867
IRF2
M05545_2.00 		Homo sapiens
NGAAAVYGAAAS
STTTCRBTTTCN		 SELEX
Yin et al.(2017)
IRF2_FL_HT-SELEX 		0.867 0.867
IRF2
M02691_2.00 		Homo sapiens
SGAAAGYGAAASYNWWHH
DDWWNRSTTTCRCTTTCS		 SELEX
Mathelier et al.(2014)
MA0051.1 		0.867 0.867
IRF2
M09237_2.00 		Homo sapiens
NRAANNGAAASYGAAASYRV
BYRSTTTCRSTTTCNNTTYN		 Misc
Kulakovskiy et al.(2013)
IRF2_HUMAN.H11MO.0.A 		0.867 0.867
Irf2
M09245_2.00 		Mus musculus
NRAANNGAAASYGAAASYRV
BYRSTTTCRSTTTCNNTTYN		 Misc
Kulakovskiy et al.(2013)
IRF2_MOUSE.H11MO.0.B 		0.867 0.867
IRF2
M09596_2.00 		Homo sapiens
NRAAVNRRAASB
VSTTYYNBTTYN		 Misc
Heinz et al.(2010)
Erythroblas-IRF2_GSE36985 		0.867 0.867
IRF2
M10892_2.00 		Homo sapiens
GAAAAGYGAAASY
RSTTTCRCTTTTC		 Transfac
Matys et al.(2006)
V$IRF2_01 		0.867 0.867
IRF2
M10893_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF2_Q6 		0.867 0.867
IRF2
M05546_2.00 		Homo sapiens
NGAAASYGAAAS
STTTCRSTTTCN		 SELEX
Yin et al.(2017)
IRF2_FL_Methyl-HT-SELEX 		0.867 0.867
IRF1
M08142_2.00 		Homo sapiens
RWANNGAAASYGAAASYRNNN
NNNYRSTTTCRSTTTCNNTWY		 ChIP-seq
Mathelier et al.(2014)
MA0050.2 		0.752 0.752
IRF1
M09233_2.00 		Homo sapiens
NRAANNGAAASWGAAASHRN
NYDSTTTCWSTTTCNNTTYN		 Misc
Kulakovskiy et al.(2013)
IRF1_HUMAN.H11MO.0.A 		0.752 0.752
Irf1
M09242_2.00 		Mus musculus
VRAANNGAAASYGAAASYVN
NBRSTTTCRSTTTCNNTTYB		 Misc
Kulakovskiy et al.(2013)
IRF1_MOUSE.H11MO.0.A 		0.752 0.752
IRF1
M09594_2.00 		Homo sapiens
GAAASTGAAASY
RSTTTCASTTTC		 Misc
Heinz et al.(2010)
PBMC-IRF1_GSE43036 		0.752 0.752
IRF1
M10879_2.00 		Homo sapiens
SAAAASYGAAASY
RSTTTCRSTTTTS		 Transfac
Matys et al.(2006)
V$IRF1_01 		0.752 0.752
IRF1
M10880_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF1_03 		0.752 0.752
IRF1
M10881_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF1_Q5 		0.752 0.752
IRF1
M10882_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF1_Q6 		0.752 0.752
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000107609 IRF 7 112
ENSDARP00000115520 IRF 7 112
ENSDARP00000123792 IRF 12 117

Links

Other IRF family TFs
Other Danio rerio TFs

132 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
IRF2 Erinaceus europaeus ENSEEUG00000004690 I 0.915
irf2 Takifugu rubripes ENSTRUG00000001842 I 0.886
ENSPFOG00000006505 Poecilia formosa ENSPFOG00000006505 I 0.876
ENSXMAG00000004071 Xiphophorus maculatus ENSXMAG00000004071 I 0.876
irf2 Danio rerio ENSDARG00000040465 I 0.876
IRF2 Pan troglodytes ENSPTRG00000016639 I 0.876
ENSMPUG00000011075 Mustela putorius furo ENSMPUG00000011075 I 0.867
IRF2 Monodelphis domestica ENSMODG00000004393 I 0.867
Irf2 Mus musculus ENSMUSG00000031627 D 0.867
irf2 Xenopus tropicalis XB-GENE-942910 I 0.867
IRF2 Oryctolagus cuniculus ENSOCUG00000009229 I 0.867
ENSNLEG00000010848 Nomascus leucogenys ENSNLEG00000010848 I 0.867
IRF2 Macaca mulatta ENSMMUG00000015087 I 0.867
IRF2 Myotis lucifugus ENSMLUG00000014246 I 0.867
ENSLACG00000004013 Latimeria chalumnae ENSLACG00000004013 I 0.867
IRF2 Gorilla gorilla ENSGGOG00000016559 I 0.867
IRF2 Loxodonta africana ENSLAFG00000000088 I 0.867
ENSLOCG00000013738 Lepisosteus oculatus ENSLOCG00000013738 I 0.867
IRF2 Microcebus murinus ENSMICG00000015506 I 0.867
IRF2 Otolemur garnettii ENSOGAG00000010966 I 0.867
irf2 Oryzias latipes ENSORLG00000008574 I 0.867
IRF2 Tursiops truncatus ENSTTRG00000009391 I 0.867
Myotis_brandtii_IRF2_10027054 Myotis brandtii Myotis_brandtii_IRF2_10027054 I 0.867
Gfo_R010481 Geospiza fortis Gfo_R010481 I 0.867
Afo_R013359 Aptenodytes forsteri Afo_R013359 I 0.867
ENSBTAP00000013193-D1 Bos grunniens ENSBTAP00000013193-D1 I 0.867
Brh_R001640 Buceros rhinoceros Brh_R001640 I 0.867
IRF2 Taeniopygia guttata ENSTGUG00000006662 I 0.867
IRF2 Sus scrofa ENSSSCG00000015782 I 0.867
Tal_R005926 Tyto alba Tal_R005926 I 0.867
irf2.S Xenopus laevis XB-GENE-17339545 I 0.867
Pvit_12337 Pogona vitticeps Pvit_12337 I 0.867
IRF2 Gallus gallus ENSGALG00000010642 I 0.867
IRF2 Pteropus vampyrus ENSPVAG00000007078 I 0.867
ENSP00000377218 Macaca fascicularis ENSP00000377218 I 0.867
ENSOARG00000007443 Ovis aries ENSOARG00000007443 I 0.867
ENSAPLG00000015442 Anas platyrhynchos ENSAPLG00000015442 I 0.867
IRF2 Felis catus ENSFCAG00000030144 I 0.867
IRF2 Cavia porcellus ENSCPOG00000013097 I 0.867
ENSFALG00000011727 Ficedula albicollis ENSFALG00000011727 I 0.867
ENSAMXG00000005897 Astyanax mexicanus ENSAMXG00000005897 I 0.867
IRF2 Callithrix jacchus ENSCJAG00000005731 I 0.867
ENSCSAG00000003010 Chlorocebus sabaeus ENSCSAG00000003010 I 0.867
IRF2 Canis familiaris ENSCAFG00000007761 I 0.867
ENSAMEG00000008380 Ailuropoda melanoleuca ENSAMEG00000008380 I 0.867
IRF2 Bos taurus ENSBTAG00000010002 I 0.867
IRF2 Homo sapiens ENSG00000168310 D 0.867
irf2 Gasterosteus aculeatus ENSGACG00000018763 I 0.867
IRF2 Choloepus hoffmanni ENSCHOG00000012067 I 0.863
Aan_R004209 Calypte anna Aan_R004209 I 0.857
Ogr17358 Ophisaurus gracilis Ogr17358 I 0.857
Irf2 Rattus norvegicus ENSRNOG00000009824 I 0.857
irf2.L Xenopus laevis XB-GENE-942916 I 0.857
IRF2 Meleagris gallopavo ENSMGAG00000006359 I 0.857
Cmyd_10017697 Chelonia mydas Cmyd_10017697 I 0.857
ENSSHAG00000002124 Sarcophilus harrisii ENSSHAG00000002124 I 0.857
IRF2 Equus caballus ENSECAG00000007508 I 0.857
ENSTSYG00000003453 Tarsius syrichta ENSTSYG00000003453 I 0.855
ENSPSIG00000016830 Pelodiscus sinensis ENSPSIG00000016830 I 0.848
ENSGMOG00000016692 Gadus morhua ENSGMOG00000016692 I 0.848
ENSONIG00000015919 Oreochromis niloticus ENSONIG00000015919 I 0.848
IRF2 Vicugna pacos ENSVPAG00000011297 I 0.848
IRF2 Ochotona princeps ENSOPRG00000005398 I 0.848
ENSMEUG00000003128 Macropus eugenii ENSMEUG00000003128 I 0.815
IRF2 Echinops telfairi ENSETEG00000003181 I 0.804
ENSLACG00000001546 Latimeria chalumnae ENSLACG00000001546 I 0.771
IRF1 Gallus gallus ENSGALG00000006785 I 0.771
Aan_R011063 Calypte anna Aan_R011063 I 0.771
Alligator_sinensis_CCG011335.1 Alligator sinensis Alligator_sinensis_CCG011335.1 I 0.768
IRF1 Meleagris gallopavo ENSMGAG00000008932 I 0.762
Gfo_R013143 Geospiza fortis Gfo_R013143 I 0.762
Brh_R004433 Buceros rhinoceros Brh_R004433 I 0.762
ENSAPLG00000009708 Anas platyrhynchos ENSAPLG00000009708 I 0.762
Tal_R004238 Tyto alba Tal_R004238 I 0.762
Afo_R012154 Aptenodytes forsteri Afo_R012154 I 0.762
ENSDORG00000003799 Dipodomys ordii ENSDORG00000003799 I 0.762
IRF1 Taeniopygia guttata ENSTGUG00000001375 I 0.762
ENSFALG00000013442 Ficedula albicollis ENSFALG00000013442 I 0.762
ENSTSYG00000001107 Tarsius syrichta ENSTSYG00000001107 I 0.756
IRF1 Sus scrofa ENSSSCG00000014277 I 0.752
ENSSTOG00000009857 Ictidomys tridecemlineatus ENSSTOG00000009857 I 0.752
ENSP00000384406-D1 Bos grunniens ENSP00000384406-D1 I 0.752
IRF1 Canis familiaris ENSCAFG00000000851 I 0.752
IRF1 Bos taurus ENSBTAG00000031231 I 0.752
Alligator_sinensis_CCG004039.1 Alligator sinensis Alligator_sinensis_CCG004039.1 I 0.752
ENSP00000384406 Macaca fascicularis ENSP00000384406 I 0.752
IRF1 Callithrix jacchus ENSCJAG00000013013 I 0.752
IRF1 Tursiops truncatus ENSTTRG00000002597 I 0.752
IRF1 Cavia porcellus ENSCPOG00000004848 I 0.752
Pvit_14395 Pogona vitticeps Pvit_14395 I 0.752
ENSMPUG00000010522 Mustela putorius furo ENSMPUG00000010522 I 0.752
Irf1 Mus musculus ENSMUSG00000018899 D 0.752
IRF1 Erinaceus europaeus ENSEEUG00000013362 I 0.752
IRF1 Equus caballus ENSECAG00000017794 I 0.752
IRF1 Macaca mulatta ENSMMUG00000008100 I 0.752
ENSAMEG00000017694 Ailuropoda melanoleuca ENSAMEG00000017694 I 0.752
ENSLOCG00000010331 Lepisosteus oculatus ENSLOCG00000010331 I 0.752
IRF1 Homo sapiens ENSG00000125347 D 0.752
IRF1 Microcebus murinus ENSMICG00000008190 I 0.752
IRF1 Felis catus ENSFCAG00000013318 I 0.752
ENSNLEG00000012720 Nomascus leucogenys ENSNLEG00000012720 I 0.752
IRF1 Ornithorhynchus anatinus ENSOANG00000010695 I 0.752
ENSPPYG00000015762 Pongo abelii ENSPPYG00000015762 I 0.752
ENSCSAG00000013810 Chlorocebus sabaeus ENSCSAG00000013810 I 0.752
IRF1 Pan troglodytes ENSPTRG00000017216 I 0.752
IRF1 Gorilla gorilla ENSGGOG00000013927 I 0.752
ENSPANG00000014875 Papio anubis ENSPANG00000014875 I 0.752
IRF1 Dasypus novemcinctus ENSDNOG00000035479 I 0.752
IRF1 Anolis carolinensis ENSACAG00000012699 I 0.752
ENSOARG00000015078 Ovis aries ENSOARG00000015078 I 0.752
IRF1 Oryctolagus cuniculus ENSOCUG00000004165 I 0.752
IRF1 Otolemur garnettii ENSOGAG00000015489 I 0.752
Irf1 Rattus norvegicus ENSRNOG00000008144 I 0.752
IRF1 Pteropus vampyrus ENSPVAG00000000430 I 0.745
IRF1 Sorex araneus ENSSARG00000006226 I 0.745
ENSMEUG00000011152 Macropus eugenii ENSMEUG00000011152 I 0.744
IRF1 Loxodonta africana ENSLAFG00000007502 I 0.743
IRF1 Procavia capensis ENSPCAG00000017088 I 0.743
IRF1 Myotis lucifugus ENSMLUG00000016545 I 0.743
Myotis_brandtii_IRF1_10032556 Myotis brandtii Myotis_brandtii_IRF1_10032556 I 0.743
ENSPSIG00000010399 Pelodiscus sinensis ENSPSIG00000010399 I 0.743
IRF1 Monodelphis domestica ENSMODG00000013963 I 0.743
ENSSHAG00000009209 Sarcophilus harrisii ENSSHAG00000009209 I 0.733
txndc15 Danio rerio ENSDARG00000043249 I 0.733
ENSPANG00000013763 Papio anubis ENSPANG00000013763 I 0.724
irf1 Xenopus tropicalis XB-GENE-942994 I 0.714
irf1.L Xenopus laevis XB-GENE-6255163 I 0.714
txndc15 Oryzias latipes ENSORLG00000001131 I 0.712
ENSAMXG00000010595 Astyanax mexicanus ENSAMXG00000010595 I 0.705
irf1.S Xenopus laevis XB-GENE-17345840 I 0.705
ENSXMAG00000011087 Xiphophorus maculatus ENSXMAG00000011087 I 0.702