Irf3 (Mus musculus)
IRF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00605 (IRF) IPR001346 ENSMUSG00000003184 T244217_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Irf3
M00174_2.00		 Mus musculus
RDWNBGMAAS
STTKCVNWHY		 PBM
Badis et al.(2009)
Irf3_3985		 (Direct) (Direct)
Irf3
M09241_2.00		 Mus musculus
RRRARDGAAAVDGRAASNRA
TYNSTTYCHBTTTCHYTYYY		 Misc
Kulakovskiy et al.(2013)
IRF3_MOUSE.H11MO.0.A		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
IRF3
M03331_2.00 		Homo sapiens
NNRRAANGGAAACCGAAACYR
YRGTTTCGGTTTCCNTTYYNN		 SELEX
Jolma et al.(2013)
IRF3_1 		0.856 0.856
IRF3
M05531_2.00 		Homo sapiens
DCVGTTTCSNSGAAACCGMAASN
NSTTKCGGTTTCSNSGAAACBGH		 SELEX
Yin et al.(2017)
IRF3_eDBD_HT-SELEX 		0.856 0.856
IRF3
M05533_2.00 		Homo sapiens
HSGAAAVBGAAACYGAAACN
NGTTTCRGTTTCVBTTTCSD		 SELEX
Yin et al.(2017)
IRF3_FL_HT-SELEX 		0.856 0.856
IRF3
M09234_2.00 		Homo sapiens
RRRARDGAAAVDGRAASNRA
TYNSTTYCHBTTTCHYTYYY		 Misc
Kulakovskiy et al.(2013)
IRF3_HUMAN.H11MO.0.B 		0.856 0.856
IRF3
M10883_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF3_Q3 		0.856 0.856
IRF3
M05532_2.00 		Homo sapiens
KCDSTTTCCHGGAAAMNRAWAV
BTWTYNKTTTCCDGGAAASHGM		 SELEX
Yin et al.(2017)
IRF3_eDBD_Methyl-HT-SELEX 		0.856 0.856
IRF3
M05534_2.00 		Homo sapiens
HGGAAABBGAAASBGAAASN
NSTTTCVSTTTCVVTTTCCD		 SELEX
Yin et al.(2017)
IRF3_FL_Methyl-HT-SELEX 		0.856 0.856
For this family, TFs with SR scores > 0.700 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00174_2.00 IRF 7 110

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000003284 IRF 7 110
ENSMUSP00000103465 IRF 7 110
ENSMUSP00000103466 IRF 7 110

Links

Other IRF family TFs
Other Mus musculus TFs

37 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Irf3 Rattus norvegicus ENSRNOG00000043388 I 0.933
ENSAMEG00000013892 Ailuropoda melanoleuca ENSAMEG00000013892 I 0.923
ENSMPUG00000002477 Mustela putorius furo ENSMPUG00000002477 I 0.923
ENSSTOG00000022900 Ictidomys tridecemlineatus ENSSTOG00000022900 I 0.913
IRF3 Homo sapiens ENSG00000126456 D 0.902
IRF3 Felis catus ENSFCAG00000006074 I 0.894
IRF3 Pteropus vampyrus ENSPVAG00000010968 I 0.894
IRF3 Tursiops truncatus ENSTTRG00000005531 I 0.894
IRF3 Myotis lucifugus ENSMLUG00000023427 I 0.875
ENSOARG00000013335 Ovis aries ENSOARG00000013335 I 0.875
Myotis_brandtii_IRF3_10017659 Myotis brandtii Myotis_brandtii_IRF3_10017659 I 0.875
IRF3 Microcebus murinus ENSMICG00000001752 I 0.873
IRF3 Bos taurus ENSBTAG00000006633 I 0.865
IRF3 Sus scrofa ENSSSCG00000003178 I 0.865
ENSBTAP00000031815-D1 Bos grunniens ENSBTAP00000031815-D1 I 0.865
IRF3 Canis familiaris ENSCAFG00000003594 I 0.857
IRF3 Equus caballus ENSECAG00000018265 I 0.856
IRF3 Gorilla gorilla ENSGGOG00000000499 I 0.856
ENSPPYG00000010260 Pongo abelii ENSPPYG00000010260 I 0.856
ENSPTRG00000011309 Pan troglodytes ENSPTRG00000011309 I 0.856
IRF3 Oryctolagus cuniculus ENSOCUG00000027558 I 0.854
IRF3 Callithrix jacchus ENSCJAG00000003637 I 0.843
ENSCSAG00000002477 Chlorocebus sabaeus ENSCSAG00000002477 I 0.837
IRF3 Macaca mulatta ENSMMUG00000022735 I 0.837
ENSPANG00000014697 Papio anubis ENSPANG00000014697 I 0.837
ENSMMUP00000031524 Macaca fascicularis ENSMMUP00000031524 I 0.837
ENSTBEG00000003466 Tupaia belangeri ENSTBEG00000003466 I 0.836
IRF3 Cavia porcellus ENSCPOG00000026146 I 0.827
ENSNLEG00000005277 Nomascus leucogenys ENSNLEG00000005277 I 0.818
IRF3 Dasypus novemcinctus ENSDNOG00000040858 I 0.817
IRF3 Procavia capensis ENSPCAG00000008633 I 0.808
IRF3 Ochotona princeps ENSOPRG00000001971 I 0.798
IRF3 Otolemur garnettii ENSOGAG00000011935 I 0.781
IRF3 Sorex araneus ENSSARG00000006248 I 0.740
ENSMEUG00000004666 Macropus eugenii ENSMEUG00000004666 I 0.729
IRF3 Loxodonta africana ENSLAFG00000028074 I 0.702