CIS-BP Database: Catalog of Inferred Sequence Binding Preferences
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Irf7
(
Rattus norvegicus
)
IRF
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF00605 (IRF)
IPR001346
ENSRNOG00000017414
T244368_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including defense response to other organism; positive regulation of type I interferon production; and regulation of toll-like receptor signaling pathway. Predicted to act upstream of or within immunoglobulin mediated immune response; positive regulation of type I interferon production; and positive regulation of type I interferon-mediated signaling pathway. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in immunodeficiency 39. Orthologous to human IRF7 (interferon regulatory factor 7). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
Irf7
M02255_2.00
Mus musculus
DAHNNGAAAN
NTTTCNNDTH
PBM
Weirauch et al.(2014)
pTH3475
0.894
0.894
Irf7
M09244_2.00
Mus musculus
RAAASYRAAW
WTTYRSTTTY
Misc
Kulakovskiy et al.(2013)
IRF7_MOUSE.H11MO.0.C
0.894
0.894
IRF7
M03337_2.00
Homo sapiens
HCGAAAVYGAAAVT
ABTTTCRBTTTCGD
SELEX
Jolma et al.(2013)
IRF7_1
0.827
0.827
IRF7
M03338_2.00
Homo sapiens
RAANCGAAAWTCGNTTY
RAANCGAWTTTCGNTTY
SELEX
Jolma et al.(2013)
IRF7_2
0.827
0.827
IRF7
M05547_2.00
Homo sapiens
NCGAAAVYGAAANYN
NRNTTTCRBTTTCGN
SELEX
Yin et al.(2017)
IRF7_eDBD_HT-SELEX
0.827
0.827
IRF7
M09238_2.00
Homo sapiens
RAAASYRAAW
WTTYRSTTTY
Misc
Kulakovskiy et al.(2013)
IRF7_HUMAN.H11MO.0.C
0.827
0.827
IRF7
M10894_2.00
Homo sapiens
NNSGAAWNYGAAANYBDV
BHVRNTTTCRNWTTCSNN
Transfac
Matys et al.(2006)
V$IRF7_01
0.827
0.827
IRF7
M05548_2.00
Homo sapiens
NNGAAARTGAAAVYR
YRBTTTCAYTTTCNN
SELEX
Yin et al.(2017)
IRF7_eDBD_Methyl-HT-SELEX
0.827
0.827
For this family, TFs with SR scores >
0.700
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSRNOP00000023504
IRF
11
122
LFGDWLLGEVSSGRYEGLQWLNEAHTVFRVPWKHFSRRDLDEADAQIFKAWAVARGRWPPSGVNLPPPEAEAAERRGWKTNFRCALRSTGRFILRQDNSGDPADPHKVYELS
Links
Other
IRF
family TFs
Other
Rattus norvegicus
TFs
25 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy