nhr-226 (Caenorhabditis elegans)
Nuclear receptor

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00105 (zf-C4) IPR001628 WBGene00020850 T306373_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in intestine. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease; hepatocellular carcinoma; lipid metabolism disorder; and myocardial infarction. Orthologous to human PPARA (peroxisome proliferator activated receptor alpha). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
T27B7.3 Nuclear receptor 6 71

Links

Other Nuclear receptor family TFs
Other Caenorhabditis elegans TFs

9 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
nhr-115 Caenorhabditis elegans WBGene00003705 N 0.926
nhr-225 Caenorhabditis elegans WBGene00020849 N 0.882
CBG01229 Caenorhabditis briggsae CBG01229 N 0.836
CBN21664 Caenorhabditis brenneri CBN21664 N 0.814
CRE09175 Caenorhabditis remanei CRE09175 N 0.804
CBN07208 Caenorhabditis brenneri CBN07208 N 0.762
nhr-180 Caenorhabditis elegans WBGene00017961 I 0.753
nhr-228 Caenorhabditis elegans WBGene00020852 N 0.751
nhr-95 Caenorhabditis elegans WBGene00003685 N 0.746