prox2 (Danio rerio)
Prospero

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF05044 (HPD) IPR007738 ENSDARG00000041952 T316448_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be active in nucleus. Is expressed in several structures, including gonad; hindbrain neural keel; immature eye; liver; and nervous system. Orthologous to human PROX2 (prospero homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
PROX1
M03445_2.00 		Homo sapiens
BAAGRCGTCTTV
BAAGACGYCTTV		 SELEX
Jolma et al.(2013)
PROX1_1 		0.791 0.791
PROX1
M05691_2.00 		Homo sapiens
BAMGRCGTCDTV
BAHGACGYCKTV		 SELEX
Yin et al.(2017)
PROX1_eDBD_HT-SELEX 		0.791 0.791
PROX1
M05692_2.00 		Homo sapiens
BAAGRYGTCTTV
BAAGACRYCTTV		 SELEX
Yin et al.(2017)
PROX1_eDBD_Methyl-HT-SELEX 		0.791 0.791
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000099298 Prospero 430 582
ENSDARP00000133530 Prospero 434 586

Links

Other Prospero family TFs
Other Danio rerio TFs

142 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSAMXG00000014376 Astyanax mexicanus ENSAMXG00000014376 I 0.922
ENSONIG00000020193 Oreochromis niloticus ENSONIG00000020193 I 0.915
ENSLOCG00000010701 Lepisosteus oculatus ENSLOCG00000010701 I 0.908
prox2 Gasterosteus aculeatus ENSGACG00000007538 I 0.889
prox2 Tetraodon nigroviridis ENSTNIG00000017414 I 0.889
prox2 Takifugu rubripes ENSTRUG00000018353 I 0.889
ENSPFOG00000014635 Poecilia formosa ENSPFOG00000014635 I 0.876
ENSGMOG00000015166 Gadus morhua ENSGMOG00000015166 I 0.869
ENSXMAG00000014663 Xiphophorus maculatus ENSXMAG00000014663 I 0.869
prox1a Tetraodon nigroviridis ENSTNIG00000016378 I 0.859
prox2 Oryzias latipes ENSORLG00000016587 I 0.851
ENSMEUG00000013465 Macropus eugenii ENSMEUG00000013465 I 0.848
prox1a Takifugu rubripes ENSTRUG00000013890 I 0.838
ENSXMAG00000003709 Xiphophorus maculatus ENSXMAG00000003709 I 0.837
prox1a Oryzias latipes ENSORLG00000014947 I 0.837
ENSPFOG00000003774 Poecilia formosa ENSPFOG00000003774 I 0.837
ENSAMXG00000012231 Astyanax mexicanus ENSAMXG00000012231 I 0.831
prox1a Gasterosteus aculeatus ENSGACG00000010140 I 0.830
ENSONIG00000013518 Oreochromis niloticus ENSONIG00000013518 I 0.830
ENSPFOG00000015503 Poecilia formosa ENSPFOG00000015503 I 0.830
ENSORLG00000001996 Oryzias latipes ENSORLG00000001996 I 0.824
prox1a Danio rerio ENSDARG00000055158 I 0.824
ENSGMOG00000009022 Gadus morhua ENSGMOG00000009022 I 0.817
ENSTRUG00000012738 Takifugu rubripes ENSTRUG00000012738 I 0.817
ENSAMXG00000011717 Astyanax mexicanus ENSAMXG00000011717 I 0.810
ENSGMOG00000001679 Gadus morhua ENSGMOG00000001679 I 0.810
ENSONIG00000012467 Oreochromis niloticus ENSONIG00000012467 I 0.805
ENSLOCG00000016698 Lepisosteus oculatus ENSLOCG00000016698 I 0.805
ENSTRUG00000010061 Takifugu rubripes ENSTRUG00000010061 I 0.805
ENSLACG00000018909 Latimeria chalumnae ENSLACG00000018909 I 0.804
ENSPFOG00000007812 Poecilia formosa ENSPFOG00000007812 N 0.797
ENSGACG00000014345 Gasterosteus aculeatus ENSGACG00000014345 I 0.792
ENSPPYG00000000224 Pongo abelii ENSPPYG00000000224 I 0.791
ENSNLEG00000014435 Nomascus leucogenys ENSNLEG00000014435 I 0.791
ENSMPUG00000013456 Mustela putorius furo ENSMPUG00000013456 I 0.791
Prox1 Rattus norvegicus ENSRNOG00000003694 I 0.791
PROX1 Macaca mulatta ENSMMUG00000011914 I 0.791
PROX1 Pan troglodytes ENSPTRG00000001974 I 0.791
ENSPSIG00000008098 Pelodiscus sinensis ENSPSIG00000008098 I 0.791
Prox1 Mus musculus ENSMUSG00000010175 I 0.791
Pvit_00353 Pogona vitticeps Pvit_00353 I 0.791
ENSAPLG00000010950 Anas platyrhynchos ENSAPLG00000010950 I 0.791
PROX1 Anolis carolinensis ENSACAG00000006174 I 0.791
ENSAMEG00000015776 Ailuropoda melanoleuca ENSAMEG00000015776 I 0.791
ENSPANG00000017714 Papio anubis ENSPANG00000017714 I 0.791
PROX1 Otolemur garnettii ENSOGAG00000017025 I 0.791
PROX1 Bos taurus ENSBTAG00000010978 I 0.791
Tal_R002989 Tyto alba Tal_R002989 I 0.791
PROX1 Myotis lucifugus ENSMLUG00000006993 I 0.791
ENSOARG00000009324 Ovis aries ENSOARG00000009324 I 0.791
PROX1 Canis familiaris ENSCAFG00000012445 I 0.791
Ogr11789 Ophisaurus gracilis Ogr11789 I 0.791
PROX1 Gallus gallus ENSGALG00000009791 I 0.791
PROX1 Gorilla gorilla ENSGGOG00000015130 I 0.791
PROX1 Cavia porcellus ENSCPOG00000011987 I 0.791
Brh_R001903 Buceros rhinoceros Brh_R001903 I 0.791
Alligator_sinensis_CCG014115.1 Alligator sinensis Alligator_sinensis_CCG014115.1 I 0.791
PROX1 Felis catus ENSFCAG00000029702 I 0.791
PROX1 Homo sapiens ENSG00000117707 D 0.791
Afo_R004723 Aptenodytes forsteri Afo_R004723 I 0.791
PROX1 Sus scrofa ENSSSCG00000015584 I 0.791
ENSBTAP00000014573-D1 Bos grunniens ENSBTAP00000014573-D1 I 0.791
PROX1 Meleagris gallopavo ENSMGAG00000009635 I 0.791
PROX1 Equus caballus ENSECAG00000019220 I 0.791
PROX1 Taeniopygia guttata ENSTGUG00000002974 I 0.791
Gfo_R010932 Geospiza fortis Gfo_R010932 I 0.791
ENSP00000355925 Macaca fascicularis ENSP00000355925 I 0.791
ENSFALG00000012357 Ficedula albicollis ENSFALG00000012357 I 0.791
PROX1 Loxodonta africana ENSLAFG00000006344 I 0.791
PROX1 Callithrix jacchus ENSCJAG00000015514 I 0.791
ENSPMAG00000006606 Petromyzon marinus ENSPMAG00000006606 I 0.786
PROX2 Tursiops truncatus ENSTTRG00000001912 I 0.784
Cmyd_10014540 Chelonia mydas Cmyd_10014540 I 0.784
Aan_R011488 Calypte anna Aan_R011488 I 0.784
ENSONIG00000015279 Oreochromis niloticus ENSONIG00000015279 I 0.784
PROX2 Felis catus ENSFCAG00000028658 I 0.784
ENSECAG00000023529 Equus caballus ENSECAG00000023529 I 0.784
PROX1 Dasypus novemcinctus ENSDNOG00000001297 I 0.784
PROX2 Myotis lucifugus ENSMLUG00000005898 I 0.784
ENSCSAG00000015530 Chlorocebus sabaeus ENSCSAG00000015530 I 0.779
ENSMPUG00000009289 Mustela putorius furo ENSMPUG00000009289 I 0.778
ENSPSIG00000017015 Pelodiscus sinensis ENSPSIG00000017015 I 0.778
PROX2 Pteropus vampyrus ENSPVAG00000000659 I 0.778
PROX2 Callithrix jacchus ENSCJAG00000020548 I 0.778
ENSAMEG00000018305 Ailuropoda melanoleuca ENSAMEG00000018305 I 0.778
Myotis_brandtii_PROX2_10012935 Myotis brandtii Myotis_brandtii_PROX2_10012935 I 0.775
PROX2 Sus scrofa ENSSSCG00000002373 I 0.773
PROX2 Pan troglodytes ENSPTRG00000006542 I 0.771
PROX2 Gorilla gorilla ENSGGOG00000022893 I 0.771
ENSOARG00000001473 Ovis aries ENSOARG00000001473 I 0.771
ENSNLEG00000016325 Nomascus leucogenys ENSNLEG00000016325 I 0.771
ENSPPYG00000005992 Pongo abelii ENSPPYG00000005992 I 0.766
ENSMICG00000006078 Microcebus murinus ENSMICG00000006078 I 0.766
prox1 Xenopus tropicalis XB-GENE-485327 I 0.766
PROX2 Canis familiaris ENSCAFG00000016985 I 0.765
PROX2 Loxodonta africana ENSLAFG00000012545 I 0.765
ENSCSAG00000012283 Chlorocebus sabaeus ENSCSAG00000012283 I 0.765
PROX2 Vicugna pacos ENSVPAG00000003072 I 0.765
ENSPANG00000024084 Papio anubis ENSPANG00000024084 I 0.765
ENSSTOG00000023253 Ictidomys tridecemlineatus ENSSTOG00000023253 I 0.765
PROX2 Bos taurus ENSBTAG00000015052 I 0.760
ENSP00000405932-D1 Bos grunniens ENSP00000405932-D1 I 0.760
PROX2 Homo sapiens ENSG00000119608 I 0.760
D917_07791 Trichinella nativa D917_07791 I 0.760
prox1.L Xenopus laevis XB-GENE-485331 I 0.758
PROX2 Ochotona princeps ENSOPRG00000011820 I 0.758
PROX2 Dasypus novemcinctus ENSDNOG00000005528 I 0.758
ENSMODG00000006137 Monodelphis domestica ENSMODG00000006137 I 0.757
Myotis_brandtii_Prox1_10018243 Myotis brandtii Myotis_brandtii_Prox1_10018243 I 0.756
PROX2 Cavia porcellus ENSCPOG00000009322 I 0.752
PROX2 Choloepus hoffmanni ENSCHOG00000000477 I 0.752
PROX2 Oryctolagus cuniculus ENSOCUG00000021246 I 0.747
PROX1 Microcebus murinus ENSMICG00000011593 I 0.745
ENSMEUG00000002316 Macropus eugenii ENSMEUG00000002316 I 0.745
PROX1 Pteropus vampyrus ENSPVAG00000009067 I 0.745
PROX1 Ochotona princeps ENSOPRG00000005115 I 0.745
PROX2 Otolemur garnettii ENSOGAG00000001327 I 0.740
D918_02805 Trichuris suis D918_02805 I 0.740
Prox2 Mus musculus ENSMUSG00000042320 I 0.739
ENSSHAG00000018304 Sarcophilus harrisii ENSSHAG00000018304 I 0.739
ACOC_0000703501 Angiostrongylus costaricensis ACOC_0000703501 I 0.737
HCOI02128500 Haemonchus contortus HCOI02128500 I 0.735
PROX2 Ornithorhynchus anatinus ENSOANG00000009815 I 0.734
PROX2 Procavia capensis ENSPCAG00000006424 I 0.732
ENSFALG00000006312 Ficedula albicollis ENSFALG00000006312 I 0.732
ENSTGUG00000012170 Taeniopygia guttata ENSTGUG00000012170 I 0.732
ENSXMAG00000009972 Xiphophorus maculatus ENSXMAG00000009972 I 0.729
Prox2 Rattus norvegicus ENSRNOG00000005054 I 0.725
Cmyd_10008872 Chelonia mydas Cmyd_10008872 I 0.719
e_gw.483.46.1 Branchiostoma floridae e_gw.483.46.1 I 0.712
Brh_R009461 Buceros rhinoceros Brh_R009461 I 0.712
ENSCING00000013650 Ciona intestinalis ENSCING00000013650 N 0.706
ENSCSAVG00000007613 Ciona savignyi ENSCSAVG00000007613 N 0.706
PROX2 Macaca mulatta ENSMMUG00000004259 N 0.705
YQE_10516 Dendroctonus ponderosae YQE_10516 I 0.700
SINV18378 Solenopsis invicta SINV18378 I 0.700
ACUA003826 Anopheles culicifacies ACUA003826 I 0.700
Cflo_00868--XP_392355.3_APIME Camponotus floridanus Cflo_00868--XP_392355.3_APIME I 0.700
AARA009757 Anopheles arabiensis AARA009757 I 0.700
AEPI001687 Anopheles epiroticus AEPI001687 I 0.700
AMIN002618 Anopheles minimus AMIN002618 I 0.700