Prox2 (Rattus norvegicus)
Prospero

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF05044 (HPD) IPR007738 ENSRNOG00000005054 T316545_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human PROX2 (prospero homeobox 2). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
PROX1
M03445_2.00 		Homo sapiens
BAAGRCGTCTTV
BAAGACGYCTTV		 SELEX
Jolma et al.(2013)
PROX1_1 		0.721 0.721
PROX1
M05691_2.00 		Homo sapiens
BAMGRCGTCDTV
BAHGACGYCKTV		 SELEX
Yin et al.(2017)
PROX1_eDBD_HT-SELEX 		0.721 0.721
PROX1
M05692_2.00 		Homo sapiens
BAAGRYGTCTTV
BAAGACRYCTTV		 SELEX
Yin et al.(2017)
PROX1_eDBD_Methyl-HT-SELEX 		0.721 0.721
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSRNOP00000006704 Prospero 435 588

Links

Other Prospero family TFs
Other Rattus norvegicus TFs

134 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
PROX2 Pteropus vampyrus ENSPVAG00000000659 I 0.903
Prox2 Mus musculus ENSMUSG00000042320 I 0.903
PROX2 Felis catus ENSFCAG00000028658 I 0.896
ENSSTOG00000023253 Ictidomys tridecemlineatus ENSSTOG00000023253 I 0.896
ENSMICG00000006078 Microcebus murinus ENSMICG00000006078 I 0.896
ENSAMEG00000018305 Ailuropoda melanoleuca ENSAMEG00000018305 I 0.896
ENSECAG00000023529 Equus caballus ENSECAG00000023529 I 0.890
PROX2 Sus scrofa ENSSSCG00000002373 I 0.890
PROX2 Tursiops truncatus ENSTTRG00000001912 I 0.890
PROX2 Callithrix jacchus ENSCJAG00000020548 I 0.883
ENSOARG00000001473 Ovis aries ENSOARG00000001473 I 0.883
PROX2 Cavia porcellus ENSCPOG00000009322 I 0.883
ENSPPYG00000005992 Pongo abelii ENSPPYG00000005992 I 0.883
ENSP00000405932-D1 Bos grunniens ENSP00000405932-D1 I 0.883
PROX2 Vicugna pacos ENSVPAG00000003072 I 0.883
PROX2 Bos taurus ENSBTAG00000015052 I 0.883
ENSNLEG00000016325 Nomascus leucogenys ENSNLEG00000016325 I 0.882
PROX2 Gorilla gorilla ENSGGOG00000022893 I 0.877
PROX2 Myotis lucifugus ENSMLUG00000005898 I 0.877
ENSPANG00000024084 Papio anubis ENSPANG00000024084 I 0.877
PROX2 Pan troglodytes ENSPTRG00000006542 I 0.877
PROX2 Ochotona princeps ENSOPRG00000011820 I 0.877
ENSMPUG00000009289 Mustela putorius furo ENSMPUG00000009289 I 0.877
PROX2 Otolemur garnettii ENSOGAG00000001327 I 0.877
PROX2 Dasypus novemcinctus ENSDNOG00000005528 I 0.877
PROX2 Canis familiaris ENSCAFG00000016985 I 0.877
Myotis_brandtii_PROX2_10012935 Myotis brandtii Myotis_brandtii_PROX2_10012935 I 0.873
PROX2 Homo sapiens ENSG00000119608 I 0.870
ENSCSAG00000012283 Chlorocebus sabaeus ENSCSAG00000012283 I 0.870
PROX2 Choloepus hoffmanni ENSCHOG00000000477 I 0.870
PROX2 Loxodonta africana ENSLAFG00000012545 I 0.864
PROX2 Oryctolagus cuniculus ENSOCUG00000021246 I 0.844
PROX2 Procavia capensis ENSPCAG00000006424 I 0.843
ENSMODG00000006137 Monodelphis domestica ENSMODG00000006137 I 0.842
ENSSHAG00000018304 Sarcophilus harrisii ENSSHAG00000018304 I 0.838
ENSMEUG00000002316 Macropus eugenii ENSMEUG00000002316 I 0.825
PROX2 Ornithorhynchus anatinus ENSOANG00000009815 I 0.812
PROX2 Macaca mulatta ENSMMUG00000004259 N 0.803
Cmyd_10014540 Chelonia mydas Cmyd_10014540 I 0.792
prox1a Tetraodon nigroviridis ENSTNIG00000016378 I 0.788
ENSMEUG00000013465 Macropus eugenii ENSMEUG00000013465 I 0.788
ENSPSIG00000017015 Pelodiscus sinensis ENSPSIG00000017015 I 0.779
ENSTGUG00000012170 Taeniopygia guttata ENSTGUG00000012170 I 0.773
ENSFALG00000006312 Ficedula albicollis ENSFALG00000006312 I 0.773
ENSPMAG00000006606 Petromyzon marinus ENSPMAG00000006606 I 0.767
Pvit_01205 Pogona vitticeps Pvit_01205 I 0.766
Brh_R009461 Buceros rhinoceros Brh_R009461 I 0.760
Ogr08018 Ophisaurus gracilis Ogr08018 N 0.760
ENSGALG00000023113 Gallus gallus ENSGALG00000023113 N 0.753
Alligator_sinensis_CCG009660.1 Alligator sinensis Alligator_sinensis_CCG009660.1 I 0.750
PROX2 Anolis carolinensis ENSACAG00000016714 N 0.747
ENSLACG00000018909 Latimeria chalumnae ENSLACG00000018909 I 0.747
PROX2 Meleagris gallopavo ENSMGAG00000012715 N 0.747
ENSAPLG00000002994 Anas platyrhynchos ENSAPLG00000002994 N 0.739
ENSGMOG00000015166 Gadus morhua ENSGMOG00000015166 I 0.727
ENSLOCG00000010701 Lepisosteus oculatus ENSLOCG00000010701 I 0.727
ENSAMXG00000012231 Astyanax mexicanus ENSAMXG00000012231 I 0.727
prox2 Danio rerio ENSDARG00000041952 I 0.725
ENSLACG00000013691 Latimeria chalumnae ENSLACG00000013691 I 0.723
PROX1 Pan troglodytes ENSPTRG00000001974 I 0.721
ENSPPYG00000000224 Pongo abelii ENSPPYG00000000224 I 0.721
PROX1 Sus scrofa ENSSSCG00000015584 I 0.721
ENSPSIG00000008098 Pelodiscus sinensis ENSPSIG00000008098 I 0.721
Prox1 Rattus norvegicus ENSRNOG00000003694 I 0.721
ENSAPLG00000010950 Anas platyrhynchos ENSAPLG00000010950 I 0.721
PROX1 Bos taurus ENSBTAG00000010978 I 0.721
Brh_R001903 Buceros rhinoceros Brh_R001903 I 0.721
Gfo_R010932 Geospiza fortis Gfo_R010932 I 0.721
Ogr11789 Ophisaurus gracilis Ogr11789 I 0.721
Pvit_00353 Pogona vitticeps Pvit_00353 I 0.721
Tal_R002989 Tyto alba Tal_R002989 I 0.721
ENSP00000355925 Macaca fascicularis ENSP00000355925 I 0.721
ENSBTAP00000014573-D1 Bos grunniens ENSBTAP00000014573-D1 I 0.721
ENSTRUG00000012738 Takifugu rubripes ENSTRUG00000012738 I 0.721
ENSAMEG00000015776 Ailuropoda melanoleuca ENSAMEG00000015776 I 0.721
Afo_R004723 Aptenodytes forsteri Afo_R004723 I 0.721
Alligator_sinensis_CCG014115.1 Alligator sinensis Alligator_sinensis_CCG014115.1 I 0.721
PROX1 Taeniopygia guttata ENSTGUG00000002974 I 0.721
ENSPFOG00000003774 Poecilia formosa ENSPFOG00000003774 I 0.721
PROX1 Myotis lucifugus ENSMLUG00000006993 I 0.721
PROX1 Meleagris gallopavo ENSMGAG00000009635 I 0.721
ENSMPUG00000013456 Mustela putorius furo ENSMPUG00000013456 I 0.721
Prox1 Mus musculus ENSMUSG00000010175 I 0.721
ENSNLEG00000014435 Nomascus leucogenys ENSNLEG00000014435 I 0.721
PROX1 Cavia porcellus ENSCPOG00000011987 I 0.721
PROX1 Loxodonta africana ENSLAFG00000006344 I 0.721
prox1a Danio rerio ENSDARG00000055158 I 0.721
PROX1 Felis catus ENSFCAG00000029702 I 0.721
ENSFALG00000012357 Ficedula albicollis ENSFALG00000012357 I 0.721
PROX1 Homo sapiens ENSG00000117707 D 0.721
PROX1 Gallus gallus ENSGALG00000009791 I 0.721
PROX1 Gorilla gorilla ENSGGOG00000015130 I 0.721
PROX1 Callithrix jacchus ENSCJAG00000015514 I 0.721
PROX1 Macaca mulatta ENSMMUG00000011914 I 0.721
ENSONIG00000013518 Oreochromis niloticus ENSONIG00000013518 I 0.721
ENSPANG00000017714 Papio anubis ENSPANG00000017714 I 0.721
prox1a Oryzias latipes ENSORLG00000014947 I 0.721
ENSOARG00000009324 Ovis aries ENSOARG00000009324 I 0.721
PROX1 Otolemur garnettii ENSOGAG00000017025 I 0.721
PROX1 Canis familiaris ENSCAFG00000012445 I 0.721
PROX1 Anolis carolinensis ENSACAG00000006174 I 0.721
PROX1 Equus caballus ENSECAG00000019220 I 0.721
D918_02805 Trichuris suis D918_02805 I 0.720
ENSTRUG00000010061 Takifugu rubripes ENSTRUG00000010061 I 0.719
ENSONIG00000020193 Oreochromis niloticus ENSONIG00000020193 I 0.714
ENSLOCG00000016698 Lepisosteus oculatus ENSLOCG00000016698 I 0.714
ENSORLG00000001996 Oryzias latipes ENSORLG00000001996 I 0.714
PROX1 Dasypus novemcinctus ENSDNOG00000001297 I 0.714
prox1a Gasterosteus aculeatus ENSGACG00000010140 I 0.714
ENSGMOG00000009022 Gadus morhua ENSGMOG00000009022 I 0.714
ENSAMXG00000011717 Astyanax mexicanus ENSAMXG00000011717 I 0.714
Aan_R011488 Calypte anna Aan_R011488 I 0.714
ENSONIG00000012467 Oreochromis niloticus ENSONIG00000012467 I 0.714
ENSAMXG00000014376 Astyanax mexicanus ENSAMXG00000014376 I 0.714
ENSCSAG00000015530 Chlorocebus sabaeus ENSCSAG00000015530 I 0.714
ENSXMAG00000003709 Xiphophorus maculatus ENSXMAG00000003709 I 0.714
ACOC_0000703501 Angiostrongylus costaricensis ACOC_0000703501 I 0.711
prox1a Takifugu rubripes ENSTRUG00000013890 I 0.708
prox2 Takifugu rubripes ENSTRUG00000018353 I 0.708
prox2 Tetraodon nigroviridis ENSTNIG00000017414 I 0.708
ENSPFOG00000015503 Poecilia formosa ENSPFOG00000015503 I 0.708
DICVIV_00921 Dictyocaulus viviparus DICVIV_00921 I 0.700
PROX1 Pteropus vampyrus ENSPVAG00000009067 I 0.700
NECAME_07738 Necator americanus NECAME_07738 I 0.700
nOo.2.0.1.g10265 Onchocerca ochengi nOo.2.0.1.g10265 I 0.700
SVUK_0000405601 Strongylus vulgaris SVUK_0000405601 I 0.700
D917_07791 Trichinella nativa D917_07791 I 0.700
ANCDUO_15205 Ancylostoma duodenale ANCDUO_15205 I 0.700
ANCCAN_23624 Ancylostoma caninum ANCCAN_23624 I 0.700
PROX1 Microcebus murinus ENSMICG00000011593 I 0.700
ANCCAN_24706 Ancylostoma caninum ANCCAN_24706 I 0.700
ANCCEY_02877 Ancylostoma ceylanicum ANCCEY_02877 I 0.700
PROX1 Ochotona princeps ENSOPRG00000005115 I 0.700
CGOC_0000822101 Cylicostephanus goldi CGOC_0000822101 I 0.700