ENSP00000332973-D1 (Bos grunniens)
SMAD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF03165 (MH1) IPR003619 ENSP00000332973-D1 T325294_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. [provided by RefSeq, Apr 2009]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Smad3
M00192_2.00
Mus musculus
NNNNNMGMCN

NGKCKNNNNN
PBM
Badis et al.(2009)
Smad3_3805
1.000 1.000
SMAD3
M03482_2.00
Homo sapiens
YGTCTAGACA

TGTCTAGACR
SELEX
Jolma et al.(2013)
SMAD3_1
1.000 1.000
SMAD3
M09380_2.00
Homo sapiens
NBCTSHCWSCWB

VWGSWGDSAGVN
Misc
Kulakovskiy et al.(2013)
SMAD3_HUMAN.H11MO.0.B
1.000 1.000
Smad3
M09384_2.00
Mus musculus
NBCTSHCWSCWB

VWGSWGDSAGVN
Misc
Kulakovskiy et al.(2013)
SMAD3_MOUSE.H11MO.0.B
1.000 1.000
Smad3
M09637_2.00
Mus musculus
BYAGMCWN

NWGKCTRV
Misc
Heinz et al.(2010)
NPC-Smad3_GSE36673
1.000 1.000
SMAD3
M11283_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SMAD3_Q6_01
1.000 1.000
SMAD3
M11284_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SMAD3_Q6_02
1.000 1.000
SMAD3
M11285_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SMAD3_Q6
1.000 1.000
SMAD9
M11274_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SMAD8_01
0.723 0.723
Smad9
M11290_2.00
Rattus norvegicus Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SMAD8_02
0.723 0.723
Smad9
M11289_2.00
Mus musculus Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SMAD8_03
0.723 0.723
Mad
M06446_2.00
Drosophila melanogaster
GYGHCGBCVS

SBGVCGDCRC
B1H
Zhu et al.(2011)
Mad_FlyReg_FBgn0011648
0.703 0.703
Mad
M08427_2.00
Drosophila melanogaster
SNGRCGMSRVSRBNS

SNVYSBYSKCGYCNS
ChIP-chip
Mathelier et al.(2014)
MA0535.1
0.703 0.703
Mad
M09692_2.00
Drosophila melanogaster
KCBGSHGKCGCSNC

GNSGCGMCDSCVGM
Misc
Kulakovskiy et al.(2009)
Mad
0.703 0.703
Mad
M11293_2.00
Drosophila melanogaster Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
I$MAD_Q6
0.703 0.703
SMAD1
M11286_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SMAD1_01
0.703 0.703
SMAD1
M11287_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SMAD1_Q6
0.703 0.703
Smad5
M11288_2.00
Mus musculus Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SMAD5_01
0.703 0.703
Smad5
M11292_2.00
Rattus norvegicus Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$SMAD5_03
0.703 0.703
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000332973-D1 SMAD 31 131

Links

Other SMAD family TFs
Other Bos grunniens TFs

269 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
AFUA_3G15290 Aspergillus fumigatus CADAFUAG00005101 N 0.000
CIMG_03174 Coccidioides immitis CIMG_03174 N 0.000
H101_04120 Trichophyton interdigitale H101_04120 N 0.000
H102_01331 Trichophyton rubrum H102_01331 N 0.000
H105_01350 Trichophyton soudanense H105_01350 N 0.000
MCYG_06599 Microsporum canis MCYG_06599 N 0.000
MGYG_07099 Microsporum gypseum MGYG_07099 N 0.000
OIDMADRAFT_182714 Oidiodendron maius OIDMADRAFT_182714 N 0.000
TEQG_04895 Trichophyton equinum TEQG_04895 N 0.000
TESG_04846 Trichophyton tonsurans TESG_04846 N 0.000
UREG_07036 Uncinocarpus reesii UREG_07036 N 0.000