| NCBI Gene Info:Enables identical protein binding activity and telomeric DNA binding activity. Involved in mitochondrial DNA metabolic process. Located in chromosome, telomeric region and mitochondrial nucleoid. Is expressed in dorsal nerve cord; head muscle; head neurons; oocyte; and ventral nerve cord. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; Parkinson's disease; amyotrophic lateral sclerosis; and mitochondrial DNA depletion syndrome 15. Orthologous to human TFAM (transcription factor A, mitochondrial). [provided by Alliance of Genome Resources, Apr 2022] |