ABF2 (Saccharomyces cerevisiae)
Sox

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00505 (HMG_box) IPR000910 YMR072W T333324_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA binding activity, bending. Involved in mitochondrial DNA packaging; mitochondrial genome maintenance; and mitochondrion inheritance. Located in mitochondrial chromosome. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; congestive heart failure; and syndromic microphthalmia 13. Orthologous to several human genes including HMGB1 (high mobility group box 1); HMGB2 (high mobility group box 2); and HMGB3 (high mobility group box 3). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ABF2
M00069_2.00		 Saccharomyces cerevisiae
NNCTCTAGASN
NSTCTAGAGNN		 PBM
Badis et al.(2008)
ABF2_2116		 (Direct) (Direct)
ABF2
M07497_2.00		 Saccharomyces cerevisiae
TCTAGAN
NTCTAGA		 PBM, CSA and or DIP-chip
Mathelier et al.(2014)
MA0266.1		 (Direct) (Direct)
ABF2
M08605_2.00		 Saccharomyces cerevisiae
TCTAGAN
NTCTAGA		 Misc
DeBoer et al.(2011)
YMR072W_541		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.415 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00069_2.00 Sox 42 110
M00069_2.00 Sox 115 182

DNA Binding Domains

Protein ID Domain From To Sequence
YMR072W Sox 43 111
YMR072W Sox 116 183

Links

Other Sox family TFs
Other Saccharomyces cerevisiae TFs

Invalid Input OrderBy

5 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action