|
|
HHAL000065-PA
(Halyomorpha halys)
Sox
|
TF Information |
|---|
| Pfam ID |
Interpro ID |
Gene ID |
CIS-BP ID |
Sequence source |
| PF00505 (HMG_box) |
IPR000910 |
HHAL000065-PA |
T334836_2.00 |
Misc (2018-Jan-19) |
| NCBI Gene Info:This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] |
Directly determined binding motifs |
|---|
| Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR
Score |
DBD
Identity |
| No direct experiments |
|
|
|
|
|
Motifs from related TFs |
|---|
| Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR
Score |
DBD
Identity |
Cic
M00195_2.00 |
Mus musculus |
NNTGCTGABN |
NVTCAGCANN |
PBM
Badis et al.(2009)
Cic_3454
|
0.728
|
0.913
|
cic
M06452_2.00 |
Drosophila melanogaster |
YYCATTSA |
TSAATGRR |
B1H
Zhu et al.(2011)
cic_SANGER_5_FBgn0028386
|
0.693
|
0.841
|
gei-3
M00711_2.00 |
Caenorhabditis elegans |
NWNWMWDN |
NHWKWNWN |
PBM
Narasimhan et al.(2015)
pTH10038
|
0.678
|
0.783
|
BBX
M05763_2.00 |
Homo sapiens |
TGAWCDNYGWTCA |
TGAWCRNHGWTCA |
SELEX
Yin et al.(2017)
BBX_eDBD_HT-SELEX
|
0.462
|
0.565
|
BBX
M05764_2.00 |
Homo sapiens |
TGAACDNYGTTCA |
TGAACRNHGTTCA |
SELEX
Yin et al.(2017)
BBX_eDBD_Methyl-HT-SELEX
|
0.462
|
0.565
|
ROX1
M00070_2.00 |
Saccharomyces cerevisiae |
NRAACAATWNN |
NNWATTGTTYN |
PBM
Badis et al.(2008)
ROX1_2099
|
0.440
|
0.362
|
ROX1
M07498_2.00 |
Saccharomyces cerevisiae |
YYHATTGTTYTS |
SARAACAATDRR |
PBM, CSA and or DIP-chip
Mathelier et al.(2014)
MA0371.1
|
0.440
|
0.362
|
ROX1
M08607_2.00 |
Saccharomyces cerevisiae |
BYATTGTN |
NACAATRV |
Misc
DeBoer et al.(2011)
YPR065W_1396
|
0.440
|
0.362
|
ROX1
M11346_2.00 |
Saccharomyces cerevisiae |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
F$ROX1_Q6_01
|
0.440
|
0.362
|
ROX1
M11347_2.00 |
Saccharomyces cerevisiae |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
F$ROX1_Q6
|
0.440
|
0.362
|
bbx
M03975_2.00 |
Drosophila melanogaster |
NAACAATDNCATTGTTN |
NAACAATGNHATTGTTN |
SELEX
Nitta et al.(2015)
bbx_1
|
0.440
|
0.507
|
Bbx
M00196_2.00 |
Mus musculus |
TTCATTGA |
TCAATGAA |
PBM
Badis et al.(2009)
Bbx_3753
|
0.428
|
0.551
|
| For this family, TFs with SR scores > 0.415 will likely have a similar motif |