ENSP00000293328-D1 (Bos grunniens)
STAT

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF02864 (STAT_bind) IPR013801 ENSP00000293328-D1 T337827_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
STAT5B
M09417_2.00
Homo sapiens
NNTTCYMRGAAN

NTTCYKRGAANN
Misc
Kulakovskiy et al.(2013)
STA5B_HUMAN.H11MO.0.A
0.992 0.992
STAT5B
M11371_2.00
Homo sapiens
NDWTTCYNGGAAWHN

NDWTTCCNRGAAWHN
Transfac
Matys et al.(2006)
V$STAT5B_01
0.992 0.992
Stat5b
M09421_2.00
Mus musculus
NNTTCYMRGAAN

NTTCYKRGAANN
Misc
Kulakovskiy et al.(2013)
STA5B_MOUSE.H11MO.0.A
0.984 0.984
Stat5a
M09420_2.00
Mus musculus
TTCYMRGAAN

NTTCYKRGAA
Misc
Kulakovskiy et al.(2013)
STA5A_MOUSE.H11MO.0.A
0.963 0.963
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000293328-D1 STAT 332 582

Links

Other STAT family TFs
Other Bos grunniens TFs

105 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSMPUG00000010528 Mustela putorius furo ENSMPUG00000010528 I 1.000
STAT5B Bos taurus ENSBTAG00000010125 I 1.000
ENSFCAG00000028112 Felis catus ENSFCAG00000028112 I 1.000
STAT5B Equus caballus ENSECAG00000007847 I 0.996
STAT5B Canis familiaris ENSCAFG00000015509 I 0.996
ENSOARG00000018964 Ovis aries ENSOARG00000018964 I 0.996
STAT5B Sus scrofa ENSSSCG00000017406 I 0.996
ENSAMEG00000006061 Ailuropoda melanoleuca ENSAMEG00000006061 I 0.996
STAT5B Gorilla gorilla ENSGGOG00000008216 I 0.992
STAT5B Tursiops truncatus ENSTTRG00000006684 I 0.992
STAT5B Homo sapiens ENSG00000173757 D 0.992
STAT5B Pan troglodytes ENSPTRG00000009198 I 0.992
ENSPANG00000021460 Papio anubis ENSPANG00000021460 I 0.992
STAT5B Ochotona princeps ENSOPRG00000008312 I 0.992
ENSPPYG00000008394 Pongo abelii ENSPPYG00000008394 I 0.992
ENSNLEG00000011444 Nomascus leucogenys ENSNLEG00000011444 I 0.992
ENSSTOG00000006691 Ictidomys tridecemlineatus ENSSTOG00000006691 I 0.992
ENSCSAG00000003133 Chlorocebus sabaeus ENSCSAG00000003133 I 0.992
ENSP00000293328 Macaca fascicularis ENSP00000293328 I 0.992
STAT5B Loxodonta africana ENSLAFG00000014045 I 0.988
STAT5B Myotis lucifugus ENSMLUG00000012050 I 0.988
Myotis_brandtii_STAT5B_10015330 Myotis brandtii Myotis_brandtii_STAT5B_10015330 I 0.988
Stat5b Rattus norvegicus ENSRNOG00000019075 I 0.988
STAT5B Oryctolagus cuniculus ENSOCUG00000005078 I 0.984
Stat5b Mus musculus ENSMUSG00000020919 D 0.984
ENSFCAG00000002153 Felis catus ENSFCAG00000002153 I 0.984
ENSSARG00000014205 Sorex araneus ENSSARG00000014205 I 0.979
Stat5a Rattus norvegicus ENSRNOG00000019496 I 0.975
ENSMODG00000014836 Monodelphis domestica ENSMODG00000014836 I 0.975
STAT5A Bos taurus ENSBTAG00000009496 I 0.975
ENSSHAG00000003879 Sarcophilus harrisii ENSSHAG00000003879 I 0.975
ENSBTAP00000034715-D1 Bos grunniens ENSBTAP00000034715-D1 I 0.975
STAT5A Erinaceus europaeus ENSEEUG00000003642 I 0.971
ENSAMEG00000006086 Ailuropoda melanoleuca ENSAMEG00000006086 I 0.971
STAT5A Tursiops truncatus ENSTTRG00000007155 I 0.971
STAT5A Sus scrofa ENSSSCG00000017402 I 0.971
ENSMPUG00000010517 Mustela putorius furo ENSMPUG00000010517 I 0.971
ENSOARG00000000809 Ovis aries ENSOARG00000000809 I 0.970
STAT5A Echinops telfairi ENSETEG00000008535 I 0.968
ENSCPOG00000026466 Cavia porcellus ENSCPOG00000026466 I 0.967
STAT5A Canis familiaris ENSCAFG00000015346 I 0.967
STAT5A Oryctolagus cuniculus ENSOCUG00000023066 I 0.967
ENSPPYG00000008393 Pongo abelii ENSPPYG00000008393 I 0.967
STAT5A Pan troglodytes ENSPTRG00000009199 I 0.967
STAT5A Macaca mulatta ENSMMUG00000010705 I 0.967
ENSSTOG00000006713 Ictidomys tridecemlineatus ENSSTOG00000006713 I 0.967
Alligator_sinensis_CCG021131.1 Alligator sinensis Alligator_sinensis_CCG021131.1 I 0.967
STAT5A Homo sapiens ENSG00000126561 D 0.967
ENSCSAG00000003196 Chlorocebus sabaeus ENSCSAG00000003196 I 0.967
ENSPANG00000021452 Papio anubis ENSPANG00000021452 I 0.967
STAT5A Myotis lucifugus ENSMLUG00000026308 I 0.967
Stat5a Dipodomys ordii ENSDORG00000000303 I 0.967
ENSMEUG00000006640 Macropus eugenii ENSMEUG00000006640 I 0.963
STAT5A Otolemur garnettii ENSOGAG00000001513 I 0.963
STAT5A Equus caballus ENSECAG00000012328 I 0.963
Stat5a Mus musculus ENSMUSG00000004043 D 0.963
STAT5A Procavia capensis ENSPCAG00000010107 I 0.963
STAT5A Loxodonta africana ENSLAFG00000014055 I 0.963
Afo_R011286 Aptenodytes forsteri Afo_R011286 I 0.959
STAT5A Pteropus vampyrus ENSPVAG00000003881 I 0.959
Gfo_R009045 Geospiza fortis Gfo_R009045 I 0.959
ENSTGUG00000002572 Taeniopygia guttata ENSTGUG00000002572 I 0.959
ENSOANG00000006496 Ornithorhynchus anatinus ENSOANG00000006496 I 0.959
ENSFALG00000000667 Ficedula albicollis ENSFALG00000000667 I 0.955
ENSNLEG00000027072 Nomascus leucogenys ENSNLEG00000027072 I 0.953
ENSP00000400320 Macaca fascicularis ENSP00000400320 I 0.951
Aan_R006195 Calypte anna Aan_R006195 I 0.951
STAT5B Gallus gallus ENSGALG00000003282 I 0.951
ENSMGAG00000003430 Meleagris gallopavo ENSMGAG00000003430 I 0.947
Pvit_13934 Pogona vitticeps Pvit_13934 I 0.938
ENSMODG00000014816 Monodelphis domestica ENSMODG00000014816 I 0.938
Ogr09155 Ophisaurus gracilis Ogr09155 I 0.938
Myotis_brandtii_STAT5A_10015329 Myotis brandtii Myotis_brandtii_STAT5A_10015329 I 0.936
stat5b.L Xenopus laevis XB-GENE-17341802 I 0.934
stat5b Xenopus tropicalis XB-GENE-5913743 I 0.934
ENSACAG00000017951 Anolis carolinensis ENSACAG00000017951 I 0.934
stat5b.S Xenopus laevis XB-GENE-5913744 I 0.934
STAT5B Echinops telfairi ENSETEG00000008528 I 0.932
STAT5A Cavia porcellus ENSCPOG00000012203 I 0.918
ENSLOCG00000012527 Lepisosteus oculatus ENSLOCG00000012527 I 0.914
ENSONIG00000001131 Oreochromis niloticus ENSONIG00000001131 I 0.905
stat5a Oryzias latipes ENSORLG00000003961 I 0.905
ENSLACG00000002646 Latimeria chalumnae ENSLACG00000002646 I 0.901
stat5a Gasterosteus aculeatus ENSGACG00000008634 I 0.901
stat5a Danio rerio ENSDARG00000019392 I 0.901
ENSXMAG00000005165 Xiphophorus maculatus ENSXMAG00000005165 I 0.901
ENSPFOG00000012581 Poecilia formosa ENSPFOG00000012581 I 0.897
stat5a Tetraodon nigroviridis ENSTNIG00000011707 I 0.889
STAT5B Otolemur garnettii ENSOGAG00000017198 I 0.881
stat5a Takifugu rubripes ENSTRUG00000015454 I 0.877
ENSGMOG00000014154 Gadus morhua ENSGMOG00000014154 I 0.868
ENSPFOG00000010905 Poecilia formosa ENSPFOG00000010905 I 0.864
STAT5A Ochotona princeps ENSOPRG00000008335 I 0.860
stat5b Danio rerio ENSDARG00000055588 I 0.860
stat5b Oryzias latipes ENSORLG00000014335 I 0.852
STAT5B Microcebus murinus ENSMICG00000011988 I 0.848
ENSPMAG00000009008 Petromyzon marinus ENSPMAG00000009008 I 0.840
stat5b Gasterosteus aculeatus ENSGACG00000015405 I 0.831
ENSGMOG00000015001 Gadus morhua ENSGMOG00000015001 I 0.811
SNAPOd2T00000256001 Oikopleura dioica SNAPOd2T00000256001 I 0.795
STAT5A Gorilla gorilla ENSGGOG00000017103 I 0.765
ENSAMXG00000013978 Astyanax mexicanus ENSAMXG00000013978 I 0.752
ENSOANG00000004051 Ornithorhynchus anatinus ENSOANG00000004051 I 0.746
ENSAMXG00000000480 Astyanax mexicanus ENSAMXG00000000480 I 0.728
STAT5B Pteropus vampyrus ENSPVAG00000003876 I 0.725