AAEL006595 (Aedes aegypti)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 AAEL006595 T203957_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Nkx2-3
M00497_2.00 		Mus musculus
NNRAGDRNN
NNYHCTYNN		 PBM
Berger et al.(2008)
Nkx2-3_3435 		0.677 0.842
NKX2-3
M05042_2.00 		Homo sapiens
NNBAAGTGBN
NVCACTTVNN		 SELEX
Yin et al.(2017)
NKX2-3_eDBD_HT-SELEX 		0.677 0.842
NKX2-3
M05045_2.00 		Homo sapiens
BNBAAGTGBN
NVCACTTVNV		 SELEX
Yin et al.(2017)
NKX2-3_FL_HT-SELEX 		0.677 0.842
NKX2-3
M05043_2.00 		Homo sapiens
BNBAAGTGBN
NVCACTTVNV		 SELEX
Yin et al.(2017)
NKX2-3_eDBD_Methyl-HT-SELEX_1 		0.677 0.842
NKX2-3
M05044_2.00 		Homo sapiens
SDYAACGHB
VDCGTTRHS		 SELEX
Yin et al.(2017)
NKX2-3_eDBD_Methyl-HT-SELEX_2 		0.677 0.842
NKX2-3
M05046_2.00 		Homo sapiens
BNBAAGTGBN
NVCACTTVNV		 SELEX
Yin et al.(2017)
NKX2-3_FL_Methyl-HT-SELEX_1 		0.677 0.842
NKX2-3
M05047_2.00 		Homo sapiens
SWYAACSHB
VDSGTTRWS		 SELEX
Yin et al.(2017)
NKX2-3_FL_Methyl-HT-SELEX_2 		0.677 0.842
NKX2-5
M00323_2.00 		Homo sapiens
NWYAAGTGSNN
NNSCACTTRWN		 PBM
Barrera et al.(2016)
NKX2-5_REF 		0.677 0.825
Nkx2-5
M00404_2.00 		Mus musculus
NNNRAGDRBN
NVYHCTYNNN		 PBM
Berger et al.(2008)
Nkx2-5_3436 		0.677 0.825
NKX2-5
M05346_2.00 		Homo sapiens
BHYAAGTGBN
NVCACTTRDV		 SELEX
Yin et al.(2017)
NKX2-5_FL_HT-SELEX 		0.677 0.825
Nkx2-5
M02686_2.00 		Mus musculus
WTAAKWK
MWMTTAW		 SELEX
Mathelier et al.(2014)
MA0063.1 		0.677 0.825
Nkx2-5
M08136_2.00 		Mus musculus
SYTGAGWGSYH
DRSCWCTCARS		 ChIP-seq
Mathelier et al.(2014)
MA0503.1 		0.677 0.825
NKX2-5
M09163_2.00 		Homo sapiens
BKRAGWGV
BCWCTYMV		 Misc
Kulakovskiy et al.(2013)
NKX25_HUMAN.H11MO.0.B 		0.677 0.825
Nkx2-5
M09177_2.00 		Mus musculus
NBYBRAGTGS
SCACTYVRVN		 Misc
Kulakovskiy et al.(2013)
NKX25_MOUSE.H11MO.0.A 		0.677 0.825
Nkx2-5
M09567_2.00 		Mus musculus
HBRAGWGBNN
NNVCWCTYVD		 Misc
Heinz et al.(2010)
HL1-Nkx2.5.biotin_GSE21529 		0.677 0.825
NKX2-5
M10742_2.00 		Homo sapiens
TYAAGTG
CACTTRA		 Transfac
Matys et al.(2006)
V$NKX25_01 		0.677 0.825
NKX2-5
M10743_2.00 		Homo sapiens
CWTAATTV
BAATTAWG		 Transfac
Matys et al.(2006)
V$NKX25_02 		0.677 0.825
NKX2-5
M10744_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NKX25_Q5 		0.677 0.825
NKX2-5
M10745_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NKX25_Q6 		0.677 0.825
NKX2-5
M05347_2.00 		Homo sapiens
BTYAAGTGGN
NCCACTTRAV		 SELEX
Yin et al.(2017)
NKX2-5_FL_Methyl-HT-SELEX_1 		0.677 0.825
NKX2-5
M05348_2.00 		Homo sapiens
BTYAACGAB
VTCGTTRAV		 SELEX
Yin et al.(2017)
NKX2-5_FL_Methyl-HT-SELEX_2 		0.677 0.825
NKX2-5
M00322_2.00 		Homo sapiens
NNNRNNN
NNNYNNN		 PBM
Barrera et al.(2016)
NKX2-5_R190C 		0.677 0.807
NKX2-5
M00324_2.00 		Homo sapiens
NHNNNNN
NNNNNDN		 PBM
Barrera et al.(2016)
NKX2-5_T178M 		0.677 0.807
NKX2-5
M00321_2.00 		Homo sapiens
HNAAGTRBNN
NNVYACTTND		 PBM
Barrera et al.(2016)
NKX2-5_R161P 		0.673 0.807
scro
M03854_2.00 		Drosophila melanogaster
NNBRMGTGB
VCACKYVNN		 SELEX
Nitta et al.(2015)
scro_1 		0.671 0.772
ceh-28
M08210_2.00 		Caenorhabditis elegans
AATCGATW
WATCGATT		 ChIP-seq
Contrino et al.(2012)
Mw138 		0.671 0.719
tin
M00559_2.00 		Drosophila melanogaster
NWYAAGTGGNN
NNCCACTTRWN		 PBM
Busser et al.(2012a)
Tin 		0.670 0.719
tin
M03809_2.00 		Drosophila melanogaster
BTYAAGTGSN
NSCACTTRAV		 SELEX
Nitta et al.(2015)
tin_1 		0.670 0.719
tin
M06284_2.00 		Drosophila melanogaster
BTYAAGTG
CACTTRAV		 B1H
Zhu et al.(2011)
Tin_Cell_FBgn0004110 		0.670 0.719
tin
M06285_2.00 		Drosophila melanogaster
BCTCAAGTGSVN
NBSCACTTGAGV		 B1H
Zhu et al.(2011)
tin_FlyReg_FBgn0004110 		0.670 0.719
tin
M06286_2.00 		Drosophila melanogaster
BWYAAGTR
YACTTRWV		 B1H
Zhu et al.(2011)
Tin_SOLEXA_FBgn0004110 		0.670 0.719
tin
M08421_2.00 		Drosophila melanogaster
DBTCRAGTGS
SCACTYGAVH		 ChIP-chip
Mathelier et al.(2014)
MA0247.2 		0.670 0.719
Nkx2-1
M00385_2.00 		Mus musculus
NNRAGDRN
NYHCTYNN		 PBM
Berger et al.(2008)
Titf1_1722 		0.667 0.772
Nkx2-4
M00514_2.00 		Mus musculus
NNRAGDRBNN
NNVYHCTYNN		 PBM
Berger et al.(2008)
Nkx2-4_3074 		0.667 0.772
NKX2-1
M09146_2.00 		Homo sapiens
BTKGAGWGBN
NVCWCTCMAV		 Misc
Kulakovskiy et al.(2013)
NKX21_HUMAN.H11MO.0.A 		0.667 0.772
Nkx2-1
M09171_2.00 		Mus musculus
NBTKGAGWGB
VCWCTCMAVN		 Misc
Kulakovskiy et al.(2013)
NKX21_MOUSE.H11MO.0.A 		0.667 0.772
Nkx2-1
M09563_2.00 		Mus musculus
BTBRAGWGBH
DVCWCTYVAV		 Misc
Heinz et al.(2010)
LungAC-Nkx2.1_GSE43252 		0.667 0.772
NKX2-1
M10694_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TITF1_Q3 		0.667 0.772
NKX2-1
M10695_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TTF1_Q5_01 		0.667 0.772
NKX2-1
M10696_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TTF1_Q5 		0.667 0.772
NKX2-1
M10697_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TTF1_Q6 		0.667 0.772
ceh-24
M02181_2.00 		Caenorhabditis elegans
NNRAKWRNN
NNYWMTYNN		 PBM
Weirauch et al.(2014)
pTH6327 		0.667 0.737
Nkx2-6
M00496_2.00 		Mus musculus
HYAAGTRBNN
NNVYACTTRD		 PBM
Berger et al.(2008)
Nkx2-6_3437 		0.663 0.789
NKX2-5
M00320_2.00 		Homo sapiens
NHBAAKWRN
NYWMTTVDN		 PBM
Barrera et al.(2016)
NKX2-5_K183E 		0.644 0.807
Nkx2-9
M00520_2.00 		Mus musculus
NNNRAGDRBN
NVYHCTYNNN		 PBM
Berger et al.(2008)
Nkx2-9_3082 		0.631 0.807
Nkx2-9
M00800_2.00 		Mus musculus
NNRAGDRBNN
NNVYHCTYNN		 PBM
Weirauch et al.(2013)
pTH2842 		0.631 0.807
Nkx2-9
M09215_2.00 		Mus musculus
BTCAAGKRB
VYMCTTGAV		 Misc
Kulakovskiy et al.(2013)
NKX28_MOUSE.H11MO.0.C 		0.631 0.807
Nkx2-2
M00438_2.00 		Mus musculus
NNNRAGDRN
NYHCTYNNN		 PBM
Berger et al.(2008)
Nkx2-2_2823 		0.623 0.772
Nkx2-2
M09190_2.00 		Mus musculus
NTBRAGWGBBN
NVVCWCTYVAN		 Misc
Kulakovskiy et al.(2013)
NKX22_MOUSE.H11MO.0.A 		0.623 0.772
NKX2-2
M10681_2.00 		Homo sapiens
WTAAGTRBTT
AAVYACTTAW		 Transfac
Matys et al.(2006)
V$NKX22_01 		0.623 0.772
NKX2-2
M10682_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NKX2B_Q3_01 		0.623 0.772
NKX2-2
M10683_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NKX2B_Q3 		0.623 0.772
vnd
M06551_2.00 		Drosophila melanogaster
WYTCAAGTR
YACTTGARW		 B1H
Mathelier et al.(2014)
MA0253.1 		0.623 0.754
vnd
M06377_2.00 		Drosophila melanogaster
WYTCAAGTR
YACTTGARW		 B1H
Zhu et al.(2011)
Vnd_Cell_FBgn0003986 		0.623 0.754
vnd
M06378_2.00 		Drosophila melanogaster
KYTSAAGWGY
RCWCTTSARM		 B1H
Zhu et al.(2011)
vnd_FlyReg_FBgn0003986 		0.623 0.754
vnd
M06379_2.00 		Drosophila melanogaster
BTBAAGTR
YACTTVAV		 B1H
Zhu et al.(2011)
Vnd_SOLEXA_FBgn0003986 		0.623 0.754
vnd
M09683_2.00 		Drosophila melanogaster
TCAAGTGB
VCACTTGA		 Misc
Kulakovskiy et al.(2009)
vnd 		0.623 0.754
NKX2-8
M00302_2.00 		Homo sapiens
NNRAGDRB
VYHCTYNN		 PBM
Barrera et al.(2016)
NKX2-8_REF 		0.599 0.789
NKX2-8
M05149_2.00 		Homo sapiens
BTSRAGTGBN
NVCACTYSAV		 SELEX
Yin et al.(2017)
NKX2-8_FL_HT-SELEX 		0.599 0.789
NKX2-8
M09145_2.00 		Homo sapiens
BTCAAGKRB
VYMCTTGAV		 Misc
Kulakovskiy et al.(2013)
NKX28_HUMAN.H11MO.0.C 		0.599 0.789
NKX2-8
M00301_2.00 		Homo sapiens
NNRAKDRB
VYHMTYNN		 PBM
Barrera et al.(2016)
NKX2-8_A94T 		0.599 0.789
NKX2-8
M05150_2.00 		Homo sapiens
GCARTAACGACATC
GATGTCGTTAYTGC		 SELEX
Yin et al.(2017)
NKX2-8_FL_Methyl-HT-SELEX_1 		0.599 0.789
NKX2-8
M05151_2.00 		Homo sapiens
BTSAAGTGBN
NVCACTTSAV		 SELEX
Yin et al.(2017)
NKX2-8_FL_Methyl-HT-SELEX_2 		0.599 0.789
NKX2-8
M05152_2.00 		Homo sapiens
BTBAACGAB
VTCGTTVAV		 SELEX
Yin et al.(2017)
NKX2-8_FL_Methyl-HT-SELEX_3 		0.599 0.789
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
AAEL006595-PA Homeodomain 282 338

Links

Other Homeodomain family TFs
Other Aedes aegypti TFs

753 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
AMTR_s00032p00057800 Amborella trichopoda AMTR_s00032p00057800 I
ASU_03287 Ascaris suum ASU_03287 N
BGIOSGA014440 Oryza indica BGIOSGA014440 I
Bo1g138940 Brassica oleracea Bo1g138940 I
Bostr.13158s0117 Boechera stricta Bostr.13158s0117 I
Bra001472 Brassica rapa Bra001472 I
BRADI3G52260 Brachypodium distachyon BRADI3G52260 I
BRADI5G20130 Brachypodium distachyon BRADI5G20130 I
Carubv10016289m.g Capsella rubella Carubv10016289m.g I
CBG21552 Caenorhabditis briggsae CBG21552 I
CBN19242 Caenorhabditis brenneri CBN19242 I
Ciclev10003958m.g Citrus clementina Ciclev10003958m.g I
Ciclev10033327m.g Citrus clementina Ciclev10033327m.g I
CJA02063 Caenorhabditis japonica CJA02063 I
CRE11598 Caenorhabditis remanei CRE11598 I
CRE21432 Caenorhabditis remanei CRE21432 I
Eucgr.E00175 Eucalyptus grandis Eucgr.E00175 I
evm.TU.supercontig_36.134 Carica papaya evm.TU.supercontig_36.134 I
F775_14744 Aegilops tauschii F775_14744 I
F775_18231 Aegilops tauschii F775_18231 I
gene26044-v1.0-hybrid Fragaria vesca gene26044-v1.0-hybrid I
GLYMA04G11040 Glycine max GLYMA04G11040 I
GLYMA06G45554 Glycine max GLYMA06G45554 I
GLYMA13G37903 Glycine max GLYMA13G37903 I
GRMZM2G038722 Zea mays GRMZM2G038722 I
GSMUA_Achr10G24560_001 Musa acuminata GSMUA_Achr10G24560_001 I
GSMUA_Achr11G04090_001 Musa acuminata GSMUA_Achr11G04090_001 I
GSMUA_Achr2G18090_001 Musa acuminata GSMUA_Achr2G18090_001 I
GSMUA_Achr4G27350_001 Musa acuminata GSMUA_Achr4G27350_001 I
GSMUA_Achr5G12230_001 Musa acuminata GSMUA_Achr5G12230_001 I
GSMUA_AchrUn_randomG15560_001 Musa acuminata GSMUA_AchrUn_randomG15560_001 I
Hba_17510 Heterorhabditis bacteriophora Hba_17510 I
L596_g15761 Steinernema carpocapsae L596_g15761 I
L892_g15289 Steinernema scapterisci L892_g15289 I
L893_g4334 Steinernema glaseri L893_g4334 I
L898_g22776 Steinernema monticolum L898_g22776 I
LPERR02G23410 Leersia perrieri LPERR02G23410 I
Lus10031758.g Linum usitatissimum Lus10031758.g I
Lus10036472.g Linum usitatissimum Lus10036472.g I
Lus10041142.g Linum usitatissimum Lus10041142.g I
MLOC_71418 Hordeum vulgare MLOC_71418 I
OB02G35920 Oryza brachyantha OB02G35920 I
OB04G30570 Oryza brachyantha OB04G30570 I
OBART04G23680 Oryza barthii OBART04G23680 I
OGLUM04G23630 Oryza glumaepatula OGLUM04G23630 I
OMERI04G19570 Oryza meridionalis OMERI04G19570 I
ONIVA04G19740 Oryza nivara ONIVA04G19740 I
OPUNC02G26430 Oryza punctata OPUNC02G26430 I
OPUNC04G21230 Oryza punctata OPUNC04G21230 I
orange1.1g037998m.g Citrus sinensis orange1.1g037998m.g I
orange1.1g039016m.g Citrus sinensis orange1.1g039016m.g I
ORGLA04G0202400 Oryza glaberrima ORGLA04G0202400 I
ORUFI04G25410 Oryza rufipogon ORUFI04G25410 I
OS04G0594100 Oryza sativa OS04G0594100 I
PGSC0003DMG400000027 Solanum tuberosum PGSC0003DMG400000027 I
PGSC0003DMG400020071 Solanum tuberosum PGSC0003DMG400020071 I
PGSC0003DMG400038913 Solanum tuberosum PGSC0003DMG400038913 I
Pm015303 Prunus mume Pm015303 I
POPTR_0004s02570 Populus trichocarpa POPTR_0004s02570 I
PRUPE_ppa025095mg Prunus persica PRUPE_ppa025095mg I
Sb04g031110 Sorghum bicolor Sb04g031110 I
Sb06g027180 Sorghum bicolor Sb06g027180 I
SELMODRAFT_127220 Selaginella moellendorffii SELMODRAFT_127220 I
SELMODRAFT_98669 Selaginella moellendorffii SELMODRAFT_98669 I
Si010384m.g Setaria italica Si010384m.g I
Si017704m.g Setaria italica Si017704m.g I
SMUV_0000230101 Syphacia muris SMUV_0000230101 N
Solyc01g094360.2 Solanum lycopersicum Solyc01g094360.2 I
Solyc06g083900.2 Solanum lycopersicum Solyc06g083900.2 I
TCNE_0001712701 Toxocara canis TCNE_0001712701 I
TELCIR_10880 Teladorsagia circumcincta TELCIR_10880 I
Thhalv10021926m.g Eutrema salsugineum Thhalv10021926m.g I
Traes_2AL_CC403D182 Triticum aestivum Traes_2AL_CC403D182 I
Traes_2BL_FD8C2F815 Triticum aestivum Traes_2BL_FD8C2F815 I
Traes_2DL_54E6F0446 Triticum aestivum Traes_2DL_54E6F0446 I
Traes_2DL_D39684C41 Triticum aestivum Traes_2DL_D39684C41 I
Traes_6AL_C13753B31 Triticum aestivum Traes_6AL_C13753B31 I
Traes_6DL_8BAAC240D Triticum aestivum Traes_6DL_8BAAC240D I
TRIUR3_14330 Triticum urartu TRIUR3_14330 I
TRIUR3_18702 Triticum urartu TRIUR3_18702 I
AtMYB17 Vitis vinifera VIT_15s0046g03190 I
dmd-6 Caenorhabditis elegans WBGene00007058 D