SMAD1 (Homo sapiens)
SMAD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF03165 (MH1) IPR003619 ENSG00000170365 T324630_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
SMAD1
M11286_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD1_01		 (Direct) (Direct)
SMAD1
M11287_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD1_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Smad5
M11288_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD5_01 		0.974 0.974
SMAD5
M05743_2.00 		Homo sapiens
YGTCTAGACW
WGTCTAGACR		 SELEX
Yin et al.(2017)
SMAD5_eDBD_HT-SELEX 		0.966 0.966
Smad5
M11292_2.00 		Rattus norvegicus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD5_03 		0.974 0.974
SMAD9
M11274_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD8_01 		0.948 0.948
SMAD5
M11271_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD5_02 		0.966 0.966
Smad9
M11290_2.00 		Rattus norvegicus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD8_02 		0.939 0.939
Smad9
M11289_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD8_03 		0.951 0.951
SMAD5
M11272_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD5_Q5_01 		0.966 0.966
Mad
M06446_2.00 		Drosophila melanogaster
GYGHCGBCVS
SBGVCGDCRC		 B1H
Zhu et al.(2011)
Mad_FlyReg_FBgn0011648 		0.924 0.924
SMAD5
M11273_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD5_Q5 		0.966 0.966
Mad
M08427_2.00 		Drosophila melanogaster
SNGRCGMSRVSRBNS
SNVYSBYSKCGYCNS		 ChIP-chip
Mathelier et al.(2014)
MA0535.1 		0.924 0.924
SMAD5
M05744_2.00 		Homo sapiens
CGTCTAGACR
YGTCTAGACG		 SELEX
Yin et al.(2017)
SMAD5_eDBD_Methyl-HT-SELEX 		0.966 0.966
Mad
M09692_2.00 		Drosophila melanogaster
KCBGSHGKCGCSNC
GNSGCGMCDSCVGM		 Misc
Kulakovskiy et al.(2009)
Mad 		0.924 0.924
Mad
M11293_2.00 		Drosophila melanogaster Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
I$MAD_Q6 		0.935 0.935
Smad3
M00192_2.00 		Mus musculus
NNNNNMGMCN
NGKCKNNNNN		 PBM
Badis et al.(2009)
Smad3_3805 		0.701 0.701
SMAD3
M03482_2.00 		Homo sapiens
YGTCTAGACA
TGTCTAGACR		 SELEX
Jolma et al.(2013)
SMAD3_1 		0.701 0.701
SMAD3
M09380_2.00 		Homo sapiens
NBCTSHCWSCWB
VWGSWGDSAGVN		 Misc
Kulakovskiy et al.(2013)
SMAD3_HUMAN.H11MO.0.B 		0.701 0.701
Smad3
M09384_2.00 		Mus musculus
NBCTSHCWSCWB
VWGSWGDSAGVN		 Misc
Kulakovskiy et al.(2013)
SMAD3_MOUSE.H11MO.0.B 		0.701 0.701
Smad3
M09637_2.00 		Mus musculus
BYAGMCWN
NWGKCTRV		 Misc
Heinz et al.(2010)
NPC-Smad3_GSE36673 		0.701 0.701
SMAD3
M11283_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD3_Q6_01 		0.701 0.701
SMAD3
M11284_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD3_Q6_02 		0.701 0.701
SMAD3
M11285_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD3_Q6 		0.701 0.701
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000305769 SMAD 30 131
ENSP00000377652 SMAD 30 131
ENSP00000422706 SMAD 30 58
ENSP00000424649 SMAD 30 95
ENSP00000424959 SMAD 30 106
ENSP00000425270 SMAD 30 112
ENSP00000426568 SMAD 30 131
ENSP00000427002 SMAD 30 131

Links

Other SMAD family TFs
Other Homo sapiens TFs

462 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
HSFA4A Arabidopsis thaliana AT4G18880 D
HSF4 Homo sapiens ENSG00000102878 D
OMERI02G17330 Oryza meridionalis OMERI02G17330 I
Traes_6AS_1537629B3 Triticum aestivum Traes_6AS_1537629B3 I
TCM_029630 Theobroma cacao TCM_029630 I
Si019082m.g Setaria italica Si019082m.g I
PRUPE_ppa006534mg Prunus persica PRUPE_ppa006534mg I
POPTR_0011s06820 Populus trichocarpa POPTR_0011s06820 I
POPTR_0004s06090 Populus trichocarpa POPTR_0004s06090 I
HSFA5 Oryza sativa OS02G0496100 I
ORUFI02G18130 Oryza rufipogon ORUFI02G18130 I
OPUNC02G15430 Oryza punctata OPUNC02G15430 I
ONIVA02G18700 Oryza nivara ONIVA02G18700 I
Traes_6DS_C59B6322F Triticum aestivum Traes_6DS_C59B6322F I
OGLUM02G17550 Oryza glumaepatula OGLUM02G17550 I
MTR_8g087540 Medicago truncatula MTR_8g087540 I
LPERR02G13860 Leersia perrieri LPERR02G13860 I
GRMZM2G179802 Zea mays GRMZM2G179802 I
GLYMA08G12630 Glycine max GLYMA08G12630 I
GLYMA05G29470 Glycine max GLYMA05G29470 I
AT-HSFA4A Arabidopsis lyrata fgenesh2_kg.7__2405__AT4G18880.1 I
F775_00937 Aegilops tauschii F775_00937 I
HSF4 Tursiops truncatus ENSTTRG00000010241 I
ENSSTOG00000027009 Ictidomys tridecemlineatus ENSSTOG00000027009 I
Cagra.2848s0007 Capsella grandiflora Cagra.2848s0007 I
PK09831.1 Cannabis sativa PK09831.1 I
MDP0000126826 Malus domestica MDP0000126826 I
Lus10015237.g Linum usitatissimum Lus10015237.g I
Lus10005420.g Linum usitatissimum Lus10005420.g I
Gorai.011G036400 Gossypium raimondii Gorai.011G036400 I
gene23802-v1.0-hybrid Fragaria vesca gene23802-v1.0-hybrid I
EuGene.0200010072 Micromonas sp RCC299 EuGene.0200010072 I
Eucgr.E02813 Eucalyptus grandis Eucgr.E02813 I
Carubv10027643m.g Capsella rubella Carubv10027643m.g I
Carubv10004953m.g Capsella rubella Carubv10004953m.g I
Cagra.4306s0004 Capsella grandiflora Cagra.4306s0004 I
Hsf4 Rattus norvegicus ENSRNOG00000015253 I
Bostr.3359s0057 Boechera stricta Bostr.3359s0057 I
Bostr.30275s0365 Boechera stricta Bostr.30275s0365 I
Bostr.0556s0470 Boechera stricta Bostr.0556s0470 I
mgf006947m Mimulus guttatus mgf006947m I
mgf006143m Mimulus guttatus mgf006143m I
cassava24811.valid.m1 Manihot esculenta cassava24811.valid.m1 I
cassava14764.m1 Manihot esculenta cassava14764.m1 I
Pm010169 Prunus mume Pm010169 I
ENSBTAP00000004568-D1 Bos grunniens ENSBTAP00000004568-D1 I
TRIUR3_11025 Triticum urartu TRIUR3_11025 I
Bra013358 Brassica rapa Bra013358 I
HSF4 Canis familiaris ENSCAFG00000020379 I
HSF4 Sus scrofa ENSSSCG00000002792 I
ENSAMEG00000017238 Ailuropoda melanoleuca ENSAMEG00000017238 I
BRADI3G43710 Brachypodium distachyon BRADI3G43710 I
Bra030021 Brassica rapa Bra030021 I
Bra029226 Brassica rapa Bra029226 I
Bra016998 Brassica rapa Bra016998 I
Bra016996 Brassica rapa Bra016996 I
Bra013412 Brassica rapa Bra013412 I
Bra013406 Brassica rapa Bra013406 I
HSF4 Bos taurus ENSBTAG00000003514 I
Bra012571 Brassica rapa Bra012571 I
Bra002882 Brassica rapa Bra002882 I
Bo7g106320 Brassica oleracea Bo7g106320 I
Bo4g190160 Brassica oleracea Bo4g190160 I
Bo3g157380 Brassica oleracea Bo3g157380 I
Bo2g165560 Brassica oleracea Bo2g165560 I
Bo2g165540 Brassica oleracea Bo2g165540 I
Bo1g020010 Brassica oleracea Bo1g020010 I
BGIOSGA006438 Oryza indica BGIOSGA006438 I
Hsf4 Mus musculus ENSMUSG00000033249 I
HSF4 Pteropus vampyrus ENSPVAG00000000402 I
HSF4 Pan troglodytes ENSPTRG00000034007 I
ENSPPYG00000007441 Pongo abelii ENSPPYG00000007441 I
ENSPANG00000005017 Papio anubis ENSPANG00000005017 I
HSF4 Ochotona princeps ENSOPRG00000015074 I
HSF4 Otolemur garnettii ENSOGAG00000001391 I
HSF4 Oryctolagus cuniculus ENSOCUG00000010001 I
ENSOARG00000002740 Ovis aries ENSOARG00000002740 I
ENSNLEG00000004338 Nomascus leucogenys ENSNLEG00000004338 I
HSF4 Cavia porcellus ENSCPOG00000010834 I
ENSMPUG00000005418 Mustela putorius furo ENSMPUG00000005418 I
HSF4 Macaca mulatta ENSMMUG00000005906 I
HSF4 Myotis lucifugus ENSMLUG00000011083 I
HSF4 Gorilla gorilla ENSGGOG00000011899 I
HSF4 Felis catus ENSFCAG00000014099 I
HSF4 Equus caballus ENSECAG00000016708 I
Hsf4 Dipodomys ordii ENSDORG00000015128 I
HSF4 Dasypus novemcinctus ENSDNOG00000032363 I
ENSCSAG00000003768 Chlorocebus sabaeus ENSCSAG00000003768 I
Bra016994 Brassica rapa Bra016994 N
Bo4g190190 Brassica oleracea Bo4g190190 N
Bo01835s010 Brassica oleracea Bo01835s010 N