IRF6 (Gallus gallus)
IRF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00605 (IRF) IPR001346 ENSGALG00000001405 T244098_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
IRF6
M02253_2.00		 Gallus gallus
NNMCNAAWNN
NNWTTNGKNN		 PBM
Weirauch et al.(2014)
pTH9178		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
IRF6
M02254_2.00 		Meleagris gallopavo
NRNCGAWACY
RGTWTCGNYN		 PBM
Weirauch et al.(2014)
pTH9210 		0.990 0.990
irf6.2
M02259_2.00 		Xenopus tropicalis
NVNHGAWACH
DGTWTCDNBN		 PBM
Weirauch et al.(2014)
pTH9302 		0.962 0.962
Irf6
M00176_2.00 		Mus musculus
NNNHGADASN
NSTHTCDNNN		 PBM
Badis et al.(2009)
Irf6_3803 		0.933 0.933
IRF6
M05527_2.00 		Homo sapiens
RGTWTCGNNNNNNYGAWACY
RGTWTCRNNNNNNCGAWACY		 SELEX
Yin et al.(2017)
IRF6_eDBD_HT-SELEX 		0.933 0.933
IRF6
M05529_2.00 		Homo sapiens
ACCGAAACT
AGTTTCGGT		 SELEX
Yin et al.(2017)
IRF6_FL_HT-SELEX 		0.933 0.933
IRF6
M05528_2.00 		Homo sapiens
RGTWTCGNHNNDNYGAWACY
RGTWTCRNHNNDNCGAWACY		 SELEX
Yin et al.(2017)
IRF6_eDBD_Methyl-HT-SELEX 		0.933 0.933
IRF6
M05530_2.00 		Homo sapiens
ACCGAWACY
RGTWTCGGT		 SELEX
Yin et al.(2017)
IRF6_FL_Methyl-HT-SELEX 		0.933 0.933
irf5.L
M02260_2.00 		Xenopus laevis
VNCGADACHN
NDGTHTCGNB		 PBM
Weirauch et al.(2014)
pTH9367 		0.771 0.771
Irf5
M00177_2.00 		Mus musculus
NNNHGADASH
DSTHTCDNNN		 PBM
Badis et al.(2009)
Irf5_3874 		0.724 0.724
IRF5
M03332_2.00 		Homo sapiens
YCGAAACCGAAMCY
RGKTTCGGTTTCGR		 SELEX
Jolma et al.(2013)
IRF5_1 		0.724 0.724
IRF5
M03333_2.00 		Homo sapiens
HACCGAAACYV
BRGTTTCGGTD		 SELEX
Jolma et al.(2013)
IRF5_2 		0.724 0.724
IRF5
M05535_2.00 		Homo sapiens
NCGAAACCGAWACH
DGTWTCGGTTTCGN		 SELEX
Yin et al.(2017)
IRF5_eDBD_HT-SELEX 		0.724 0.724
IRF5
M05537_2.00 		Homo sapiens
NCGAAACCGAAACY
RGTTTCGGTTTCGN		 SELEX
Yin et al.(2017)
IRF5_FL_HT-SELEX 		0.724 0.724
IRF5
M10884_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF5_Q3 		0.724 0.724
IRF5
M05536_2.00 		Homo sapiens
NYGAWACYGAWACH
DGTWTCRGTWTCRN		 SELEX
Yin et al.(2017)
IRF5_eDBD_Methyl-HT-SELEX 		0.724 0.724
IRF5
M05538_2.00 		Homo sapiens
NYGAAACCGAWACY
RGTWTCGGTTTCRN		 SELEX
Yin et al.(2017)
IRF5_FL_Methyl-HT-SELEX 		0.724 0.724
IRF5
M02256_2.00 		Oryctolagus cuniculus
NHCGAAACYN
NRGTTTCGDN		 PBM
Weirauch et al.(2014)
pTH9272 		0.714 0.714
For this family, TFs with SR scores > 0.700 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M02253_2.00 IRF 9 114

DNA Binding Domains

Protein ID Domain From To Sequence
ENSGALP00000039479 IRF 19 124

Links

Other IRF family TFs
Other Gallus gallus TFs

121 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSBTAP00000000859-D1 Bos grunniens ENSBTAP00000000859-D1 I
ENSCJAG00000000574 Callithrix jacchus ENSCJAG00000000574 I
ENSLACG00000001788 Latimeria chalumnae ENSLACG00000001788 I
ENSPMAG00000001401 Petromyzon marinus ENSPMAG00000001401 I
ENSSARG00000011370 Sorex araneus ENSSARG00000011370 I
NFATC1 Echinops telfairi ENSETEG00000010848 I
NFATC2 Ochotona princeps ENSOPRG00000016094 I
NFATC2 Tupaia belangeri ENSTBEG00000004525 I
NFATC4 Homo sapiens ENSG00000100968 D
NFATC4 Pteropus vampyrus ENSPVAG00000007042 I