CIS-BP Database: Catalog of Inferred Sequence Binding Preferences

TF Information

pax5.L *(Xenopus laevis)* Paired box
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source
PF00292 (PAX)	IPR001523	XB-GENE-865318	T312280_2.00	Misc (2018-Jan-19)
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
pax2b M02425_2.00	Danio rerio	HVNYSRNSCR	YGSNYSRNBD	PBM Weirauch et al.(2014) pTH8679	0.976	0.976
Pax5B M01301_2.00	Gallus gallus	NSNDTNNNN	NNNNAHNSN	PBM Lambert et al.(2019) pTH9781	0.976	0.976
PAX5 M03443_2.00	Homo sapiens	RNBYANYSAWSCGTRACN	NGTYACGSWTSRNTRVNY	SELEX Jolma et al.(2013) PAX5_1	0.976	0.976
PAX5 M08160_2.00	Homo sapiens	RDGCGTGACCNN	NNGGTCACGCHY	ChIP-seq Mathelier et al.(2014) MA0014.3	0.976	0.976
PAX5 M07995_2.00	Homo sapiens	BCAVYSRDSCRKRRC	GYYMYGSHYSRBTGV	ChIP-seq Gerstein et al.(2012) GM12878_PAX5C20_HudsonAlpha	0.976	0.976
PAX5 M07996_2.00	Homo sapiens	BCASYSRDSCRTRAC	GTYAYGSHYSRSTGV	ChIP-seq Gerstein et al.(2012) GM12878_PAX5N19_HudsonAlpha	0.976	0.976
PAX5 M07997_2.00	Homo sapiens	CASYSRDSCRKRACN	NGTYMYGSHYSRSTG	ChIP-seq Gerstein et al.(2012) GM12891_PAX5C20_HudsonAlpha	0.976	0.976
PAX5 M07998_2.00	Homo sapiens	BCASYSRDSCGKRRC	GYYMCGSHYSRSTGV	ChIP-seq Gerstein et al.(2012) GM12892_PAX5C20_HudsonAlpha	0.976	0.976
PAX5 M08227_2.00	Homo sapiens	BCANYSRDGCGTRAM	KTYACGCHYSRNTGV	ChIP-seq Contrino et al.(2012) Mv108	0.976	0.976
PAX5 M08228_2.00	Homo sapiens	AGCGTGRCYG	CRGYCACGCT	ChIP-seq Contrino et al.(2012) Mv109	0.976	0.976
PAX5 M09341_2.00	Homo sapiens	SNVDGNKCARCVRAGCRDGAC	GTCHYGCTYBGYTGMNCHBNS	Misc Kulakovskiy et al.(2013) PAX5_HUMAN.H11MO.0.A	0.976	0.976
Pax5 M09342_2.00	Mus musculus	VDRNBCAVYVRDSCRKRRM	KYYMYGSHYBRBTGVNYHB	Misc Kulakovskiy et al.(2013) PAX5_MOUSE.H11MO.0.A	0.976	0.976
PAX5 M09622_2.00	Homo sapiens	BCASYSRDSCRTGRMN	NKYCAYGSHYSRSTGV	Misc Heinz et al.(2010) GM12878-PAX5_GSE32465_1	0.976	0.976
PAX5 M09623_2.00	Homo sapiens	BCABNVRSCGTGAC	GTCACGSYBNVTGV	Misc Heinz et al.(2010) GM12878-PAX5_GSE32465_2	0.976	0.976
PAX5 M11208_2.00	Homo sapiens	BCNNNRNKCANBGNWGNRKRGMSRSHNB	VNDSYSKCYMYNCWNCVNTGMNYNNNGV	Transfac Matys et al.(2006) V$PAX5_01	0.976	0.976
PAX5 M11209_2.00	Homo sapiens	VRHVDGDNDBBTNRAGCGKRACVRYNVH	DBNRYBGTYMCGCTYNAVVHNHCHBDYB	Transfac Matys et al.(2006) V$PAX5_02	0.976	0.976
PAX5 M11210_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX5_06	0.976	0.976
PAX5 M11211_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX5_07	0.976	0.976
PAX5 M11212_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX5_Q6	0.976	0.976
pax2 M02428_2.00	Xenopus tropicalis	NNNRNBCRNN	NNYGVNYNNN	PBM Weirauch et al.(2014) pTH8556	0.968	0.968
PAX8 M05685_2.00	Homo sapiens	NRNBYRNYSRWGCGTGACSN	NSGTCACGCWYSRNYRVNYN	SELEX Yin et al.(2017) PAX8_FL_HT-SELEX	0.928	0.928
Pax8 M09624_2.00	Rattus norvegicus	BCAGBCADSCRKGVM	KBCMYGSHTGVCTGV	Misc Heinz et al.(2010) Thyroid-Pax8_GSE26938	0.928	0.928
PAX8 M11205_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX8_01	0.928	0.928
PAX8 M11206_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX8_B	0.928	0.928
PAX8 M05686_2.00	Homo sapiens	NRNBCRNTSAWSCGYGACNN	NNGTCRCGSWTSANYGVNYN	SELEX Yin et al.(2017) PAX8_FL_Methyl-HT-SELEX	0.928	0.928
sv M01302_2.00	Drosophila melanogaster	NNNSCRBRDM	KHYVYGSNNN	PBM Lambert et al.(2019) pTH9773	0.880	0.880
sv M03949_2.00	Drosophila melanogaster	NBCRNYSAWGCGTGACS	SGTCACGCWTSRNYGVN	SELEX Nitta et al.(2015) sv_1	0.880	0.880
sv M06438_2.00	Drosophila melanogaster	RNYSRDSCGTRACNN	NNGTYACGSHYSRNY	B1H Zhu et al.(2011) sv_SOLEXA_5_FBgn0005561	0.880	0.880
egl-38 M02426_2.00	Caenorhabditis elegans	ACCGTGAYCAC	GTGRTCACGGT	PBM Weirauch et al.(2014) pTH8981	0.744	0.744
pax-2 M00706_2.00	Caenorhabditis elegans	RMSCRTRACS	SGTYAYGSKY	PBM Narasimhan et al.(2015) pTH10794	0.744	0.744
PAX1 M03442_2.00	Homo sapiens	DBCANTSAWGCGTGACS	SGTCACGCWTSANTGVH	SELEX Jolma et al.(2013) PAX1_1	0.744	0.744
PAX1 M05687_2.00	Homo sapiens	BCRNTSRWGCGTGACSN	NSGTCACGCWYSANYGV	SELEX Yin et al.(2017) PAX1_eDBD_HT-SELEX	0.744	0.744
PAX1 M11207_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX1_B	0.744	0.744
PAX1 M05688_2.00	Homo sapiens	BCRNTSAWGCGTGACSN	NSGTCACGCWTSANYGV	SELEX Yin et al.(2017) PAX1_eDBD_Methyl-HT-SELEX	0.744	0.744
PAX9 M03444_2.00	Homo sapiens	NKCANTSAWGCGTGACS	SGTCACGCWTSANTGMN	SELEX Jolma et al.(2013) PAX9_1	0.736	0.736
Poxn M03946_2.00	Drosophila melanogaster	DGCGTGACSGTCACGSY	RSCGTGACSGTCACGCH	SELEX Nitta et al.(2015) Poxn_1	0.736	0.736
Poxn M03947_2.00	Drosophila melanogaster	RSCGKGACSGTTMCGSW	WSCGKAACSGTCMCGSY	SELEX Nitta et al.(2015) Poxn_2	0.736	0.736
Poxn M03948_2.00	Drosophila melanogaster	NCGTTCCGGAACGD	HCGTTCCGGAACGN	SELEX Nitta et al.(2015) Poxn_3	0.736	0.736
PAX9 M05689_2.00	Homo sapiens	BHRNYSRDSCGTRACSN	NSGTYACGSHYSRNYDV	SELEX Yin et al.(2017) PAX9_eDBD_HT-SELEX	0.736	0.736
Poxn M06437_2.00	Drosophila melanogaster	RSCGTGACG	CGTCACGSY	B1H Zhu et al.(2011) Poxn_SOLEXA_5_FBgn0003130	0.736	0.736
PAX9 M05690_2.00	Homo sapiens	BCRNTSAWSCGYGACNN	NNGTCRCGSWTSANYGV	SELEX Yin et al.(2017) PAX9_eDBD_Methyl-HT-SELEX	0.736	0.736
Poxm M03944_2.00	Drosophila melanogaster	CAVTCAWGCGTGACR	YGTCACGCWTGABTG	SELEX Nitta et al.(2015) Poxm_1	0.728	0.728
Poxm M03945_2.00	Drosophila melanogaster	NYSAWGCRTRACS	SGTYAYGCWTSRN	SELEX Nitta et al.(2015) Poxm_2	0.728	0.728
Poxm M06436_2.00	Drosophila melanogaster	NNNNNNMVNHNRNSCRTGA	TCAYGSNYNDNBKNNNNNN	B1H Zhu et al.(2011) Poxm_SOLEXA_5_FBgn0003129	0.728	0.728
pax9 M11204_2.00	Danio rerio	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$PAX9_B	0.728	0.728
PAX7 M00346_2.00	Homo sapiens	NGTYAYGSHN	NDSCRTRACN	PBM Barrera et al.(2016) PAX7_REF	0.720	0.720
PAX7 M00345_2.00	Homo sapiens	NSGTCACGSN	NSCGTGACSN	PBM Barrera et al.(2016) PAX7_P112L	0.712	0.712
For this family, TFs with SR scores > 0.700* will likely have a similar motif*

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
CAA09230	Paired box	15	139	RHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVDKIADYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIR

Links
Other Paired box family TFs
Other *Xenopus laevis* TFs

610 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action
Alligator_sinensis_CCG017359.1	Alligator sinensis	Alligator_sinensis_CCG017359.1	I
ENSAPLG00000007946	Anas platyrhynchos	ENSAPLG00000007946	I
HDX	Anolis carolinensis	ENSACAG00000014116	I
Afo_R014150	Aptenodytes forsteri	Afo_R014150	I
Brh_R002803	Buceros rhinoceros	Brh_R002803	I
HDX	Callithrix jacchus	ENSCJAG00000008295	I
Aan_R004747	Calypte anna	Aan_R004747	I
HDX	Canis familiaris	ENSCAFG00000017380	I
HDX	Cavia porcellus	ENSCPOG00000014501	I
Cmyd_10021519	Chelonia mydas	Cmyd_10021519	I
ENSCSAG00000010546	Chlorocebus sabaeus	ENSCSAG00000010546	I
hdx	Danio rerio	ENSDARG00000079382	I
HDX	Echinops telfairi	ENSETEG00000018031	I
HDX	Equus caballus	ENSECAG00000024862	I
HDX	Erinaceus europaeus	ENSEEUG00000011626	I
HDX	Felis catus	ENSFCAG00000005781	I
ENSFALG00000004050	Ficedula albicollis	ENSFALG00000004050	I
ENSGMOG00000004501	Gadus morhua	ENSGMOG00000004501	I
HDX	Gallus gallus	ENSGALG00000007041	I
hdx	Gasterosteus aculeatus	ENSGACG00000018543	I
Gfo_R008526	Geospiza fortis	Gfo_R008526	I
HDX	Gorilla gorilla	ENSGGOG00000005551	I
HDX	Homo sapiens	ENSG00000165259	D
ENSLACG00000001553	Latimeria chalumnae	ENSLACG00000001553	I
ENSLOCG00000015046	Lepisosteus oculatus	ENSLOCG00000015046	I
HDX	Loxodonta africana	ENSLAFG00000028655	I
ENSP00000297977	Macaca fascicularis	ENSP00000297977	I
HDX	Macaca mulatta	ENSMMUG00000020536	I
HDX	Meleagris gallopavo	ENSMGAG00000004732	I
HDX	Monodelphis domestica	ENSMODG00000014307	I
ENSMPUG00000006315	Mustela putorius furo	ENSMPUG00000006315	I
Hdx	Mus musculus	ENSMUSG00000034551	D
ENSNLEG00000002624	Nomascus leucogenys	ENSNLEG00000002624	I
Ogr06876	Ophisaurus gracilis	Ogr06876	I
ENSONIG00000017662	Oreochromis niloticus	ENSONIG00000017662	I
HDX	Oryctolagus cuniculus	ENSOCUG00000000903	I
hdx	Oryzias latipes	ENSORLG00000008466	I
HDX	Otolemur garnettii	ENSOGAG00000031446	I
ENSOARG00000001832	Ovis aries	ENSOARG00000001832	I
HDX	Pan troglodytes	ENSPTRG00000022065	I
ENSPANG00000014327	Papio anubis	ENSPANG00000014327	I
ENSPSIG00000003320	Pelodiscus sinensis	ENSPSIG00000003320	I
ENSPFOG00000004291	Poecilia formosa	ENSPFOG00000004291	I
Pvit_02951	Pogona vitticeps	Pvit_02951	I
ENSPPYG00000020514	Pongo abelii	ENSPPYG00000020514	I
Hdx	Rattus norvegicus	ENSRNOG00000037799	I
ENSSHAG00000014376	Sarcophilus harrisii	ENSSHAG00000014376	I
HDX	Sorex araneus	ENSSARG00000009351	I
HDX	Taeniopygia guttata	ENSTGUG00000002499	I
hdx	Takifugu rubripes	ENSTRUG00000008150	I
ENSTSYG00000009619	Tarsius syrichta	ENSTSYG00000009619	I
rps6kal	Tetraodon nigroviridis	ENSTNIG00000015774	I
HDX	Tursiops truncatus	ENSTTRG00000000100	I
HDX	Vicugna pacos	ENSVPAG00000003255	I
hdx	Xenopus tropicalis	XB-GENE-853748	I
ENSXMAG00000011901	Xiphophorus maculatus	ENSXMAG00000011901	I

pax5.L (Xenopus laevis) Paired box

TF Information

Directly determined binding motifs

Motifs from related TFs

DNA Binding Domains

Links

610 Related TFs

pax5.L **(Xenopus laevis)
Paired box**