Hes5 (Rattus norvegicus)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSRNOG00000013850 T037205_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
basic helix-loop-helix (HLH) protein; may function as negative regulator in neural development [RGD, Feb 2006]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Hes5
M01747_2.00
Mus musculus
NVCRCGYGBN

NVCRCGYGBN
PBM
Weirauch et al.(2014)
pTH5450
0.914 1.000
HES5
M02809_2.00
Homo sapiens
YGRCACGTGCCD

HGGCACGTGYCR
SELEX
Jolma et al.(2013)
HES5_1
0.914 1.000
HES5
M02810_2.00
Homo sapiens
YGGCACGTGCCR

YGGCACGTGCCR
SELEX
Jolma et al.(2013)
HES5_2
0.914 1.000
HES5
M04216_2.00
Homo sapiens
VRCACGTGCC

GGCACGTGYB
SELEX
Yin et al.(2017)
HES5_eDBD_HT-SELEX
0.914 1.000
HES5
M04217_2.00
Homo sapiens
VRCACGTGCC

GGCACGTGYB
SELEX
Yin et al.(2017)
HES5_eDBD_Methyl-HT-SELEX_1
0.914 1.000
HES5
M04218_2.00
Homo sapiens
VSACRCKY

RMGYGTSB
SELEX
Yin et al.(2017)
HES5_eDBD_Methyl-HT-SELEX_2
0.914 1.000
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSRNOP00000018769 bHLH 17 73

Links

Other bHLH family TFs
Other Rattus norvegicus TFs

28 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSMMUG00000014688 Macaca mulatta ENSMMUG00000014688 I 0.914
HES5 Pan troglodytes ENSPTRG00000024233 I 0.914
HES5 Gorilla gorilla ENSGGOG00000010276 I 0.914
HES5 Procavia capensis ENSPCAG00000001025 I 0.914
Hes5 Mus musculus ENSMUSG00000048001 D 0.914
HES5 Otolemur garnettii ENSOGAG00000030950 I 0.914
ENSOARG00000018071 Ovis aries ENSOARG00000018071 I 0.914
ENSPANG00000022730 Papio anubis ENSPANG00000022730 I 0.914
HES5 Tursiops truncatus ENSTTRG00000003782 I 0.914
HES5 Callithrix jacchus ENSCJAG00000002549 I 0.914
HES5 Canis familiaris ENSCAFG00000019421 I 0.914
HES5 Bos taurus ENSBTAG00000002483 I 0.914
ENSCPOG00000027139 Cavia porcellus ENSCPOG00000027139 I 0.914
ENSCSAG00000000715 Chlorocebus sabaeus ENSCSAG00000000715 I 0.914
HES5 Homo sapiens ENSG00000197921 D 0.914
HES5 Erinaceus europaeus ENSEEUG00000008377 I 0.914
ENSSHAG00000014397 Sarcophilus harrisii ENSSHAG00000014397 I 0.884
HES5 Monodelphis domestica ENSMODG00000008212 I 0.884
ENSMEUG00000013913 Macropus eugenii ENSMEUG00000013913 I 0.884
Alligator_sinensis_CCG011591.1 Alligator sinensis Alligator_sinensis_CCG011591.1 I 0.860
Brh_R011663 Buceros rhinoceros Brh_R011663 I 0.860
Afo_R003314 Aptenodytes forsteri Afo_R003314 I 0.860
Tal_R007855 Tyto alba Tal_R007855 I 0.860
Aan_R005913 Calypte anna Aan_R005913 I 0.860
HES5 Meleagris gallopavo ENSMGAG00000002009 I 0.860
HES5 Gallus gallus ENSGALG00000001141 I 0.860
ENSAPLG00000007967 Anas platyrhynchos ENSAPLG00000007967 I 0.860
ENSBTAP00000003221-D1 Bos grunniens ENSBTAP00000003221-D1 I 0.433