MGA (Homo sapiens)
bHLH,T-box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH)
PF00907 (T-box)
IPR001092
IPR001699
ENSG00000174197 T055457_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
MGA
M02821_2.00
Homo sapiens
RGGTGTGA

TCACACCY
SELEX
Jolma et al.(2013)
MGA_1
(Direct) (Direct)
MGA
M02822_2.00
Homo sapiens
AGGTGTKAHDTMACACCT

AGGTGTKAHDTMACACCT
SELEX
Jolma et al.(2013)
MGA_2
(Direct) (Direct)
MGA
M02823_2.00
Homo sapiens
VGTGTKAWWWTTCACRCB

VGYGTGAAWWWTMACACB
SELEX
Jolma et al.(2013)
MGA_3
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000219905 T-box 77 260
ENSP00000219905 bHLH 2424 2475
ENSP00000442467 T-box 77 260
ENSP00000442467 bHLH 2215 2266
ENSP00000455155 T-box 77 260
ENSP00000456141 T-box 77 260
ENSP00000456141 bHLH 2215 2266
ENSP00000457035 T-box 77 260
ENSP00000457035 bHLH 2424 2475
ENSP00000457151 T-box 77 260
ENSP00000457474 bHLH 1072 1123

Links

Other bHLH,T-box family TFs
Other Homo sapiens TFs

66 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
Aan_R008874 Calypte anna Aan_R008874 I 0.889
Afo_R002341 Aptenodytes forsteri Afo_R002341 I 0.915
Alligator_sinensis_CCG001030.1 Alligator sinensis Alligator_sinensis_CCG001030.1 N 0.915
Cmyd_10013542 Chelonia mydas Cmyd_10013542 I 0.927
ENSACAG00000014307 Anolis carolinensis ENSACAG00000014307 N 0.864
ENSAMEG00000016587 Ailuropoda melanoleuca ENSAMEG00000016587 I 0.991
ENSAMXG00000000314 Astyanax mexicanus ENSAMXG00000000314 N 0.792
ENSAPLG00000010304 Anas platyrhynchos ENSAPLG00000010304 I 0.897
ENSCSAG00000007832 Chlorocebus sabaeus ENSCSAG00000007832 I 1.000
ENSDNOG00000032105 Dasypus novemcinctus ENSDNOG00000032105 N 0.914
ENSFALG00000006030 Ficedula albicollis ENSFALG00000006030 I 0.906
ENSGALG00000008653 Gallus gallus ENSGALG00000008653 I 0.910
ENSLACG00000002619 Latimeria chalumnae ENSLACG00000002619 I 0.859
ENSLOCG00000011689 Lepisosteus oculatus ENSLOCG00000011689 I 0.769
ENSMEUG00000005571 Macropus eugenii ENSMEUG00000005571 N 0.914
ENSMMUG00000010294 Macaca mulatta ENSMMUG00000010294 N 0.920
ENSMPUG00000008968 Mustela putorius furo ENSMPUG00000008968 I 0.991
ENSNLEG00000003750 Nomascus leucogenys ENSNLEG00000003750 I 1.000
ENSOARG00000020404 Ovis aries ENSOARG00000020404 I 0.991
ENSP00000219905 Macaca fascicularis ENSP00000219905 I 1.000
ENSP00000219905-D1 Bos grunniens ENSP00000219905-D1 I 0.987
ENSPANG00000018801 Papio anubis ENSPANG00000018801 N 0.914
ENSPPYG00000006380 Pongo abelii ENSPPYG00000006380 I 1.000
ENSPSIG00000000330 Pelodiscus sinensis ENSPSIG00000000330 N 0.915
ENSPSIG00000004501 Pelodiscus sinensis ENSPSIG00000004501 N 0.915
ENSSSCG00000027182 Sus scrofa ENSSSCG00000027182 N 0.914
ENSSTOG00000000653 Ictidomys tridecemlineatus ENSSTOG00000000653 I 0.987
ENSTSYG00000014605 Tarsius syrichta ENSTSYG00000014605 I 0.996
Gfo_R014126 Geospiza fortis Gfo_R014126 I 0.910
MGA Sorex araneus ENSSARG00000007043 I 0.991
MGA Tupaia belangeri ENSTBEG00000002010 I 0.996
MGA Sus scrofa ENSSSCG00000004739 N 0.914
MGA Tursiops truncatus ENSTTRG00000002514 I 0.991
MGA Vicugna pacos ENSVPAG00000006239 I 0.987
MGA Ochotona princeps ENSOPRG00000003327 N 0.902
Mga Dipodomys ordii ENSDORG00000013098 N 0.891
Mga Rattus norvegicus ENSRNOG00000006378 I 0.974
MGA Pteropus vampyrus ENSPVAG00000013732 I 0.991
MGA Pan troglodytes ENSPTRG00000006953 I 1.000
MGA Felis catus ENSFCAG00000007347 I 0.991
MGA Loxodonta africana ENSLAFG00000012978 N 0.914
MGA Macaca mulatta ENSMMUG00000010168 N 0.914
MGA Cavia porcellus ENSCPOG00000015345 N 0.914
MGA Erinaceus europaeus ENSEEUG00000004604 I 0.983
MGA Equus caballus ENSECAG00000006544 I 0.991
MGA Callithrix jacchus ENSCJAG00000020688 I 0.996
MGA Choloepus hoffmanni ENSCHOG00000012044 I 0.987
MGA Canis familiaris ENSCAFG00000009662 I 0.991
MGA Gorilla gorilla ENSGGOG00000001640 I 1.000
MGA Procavia capensis ENSPCAG00000013131 I 0.932
MGA Otolemur garnettii ENSOGAG00000016028 I 0.991
MGA Oryctolagus cuniculus ENSOCUG00000006505 I 0.987
MGA Ornithorhynchus anatinus ENSOANG00000004502 I 0.906
Mga Mus musculus ENSMUSG00000033943 I 0.974
MGA Monodelphis domestica ENSMODG00000000052 I 0.940
MGA Myotis lucifugus ENSMLUG00000015227 I 0.987
MGA Microcebus murinus ENSMICG00000001788 I 0.991
MGA Meleagris gallopavo ENSMGAG00000011293 I 0.919
MGA Bos taurus ENSBTAG00000015138 I 0.987
Myotis_brandtii_MGA_10023843 Myotis brandtii Myotis_brandtii_MGA_10023843 I 0.910
Ogr06445 Ophisaurus gracilis Ogr06445 N 0.880
Ogr06446 Ophisaurus gracilis Ogr06446 I 0.906
Pvit_03503 Pogona vitticeps Pvit_03503 I 0.880
Tal_R011609 Tyto alba Tal_R011609 N 0.902
XP_002933783 Xenopus tropicalis XP_002933783 I 0.838