Pdp1 (Drosophila melanogaster)
bZIP

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00170 (bZIP_1) IPR011616 FBgn0016694 T062075_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in circadian rhythm; positive regulation of transcription, DNA-templated; and regulation of lipid metabolic process. Located in nucleus. Is expressed in several structures, including adult pacemaker neurons; extended germ band embryo; gut section; muscle system; and presumptive embryonic/larval system. Human ortholog(s) of this gene implicated in osteoporosis. Orthologous to several human genes including DBP (D-box binding PAR bZIP transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Pdp1
M03645_2.00		 Drosophila melanogaster
VTTACGTAAB
VTTACGTAAB		 SELEX
Nitta et al.(2015)
Pdp1_1		 (Direct) (Direct)
Pdp1
M03646_2.00		 Drosophila melanogaster
RTTACGTAAY
RTTACGTAAY		 SELEX
Nitta et al.(2015)
Pdp1_2		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
HLF
M02831_2.00 		Homo sapiens
NRTTAYRTAABN
NVTTAYRTAAYN		 SELEX
Jolma et al.(2013)
HLF_1 		0.795 0.672
Hlf
M02860_2.00 		Mus musculus
KRTTACGTAAYN
NRTTACGTAAYM		 SELEX
Jolma et al.(2013)
Hlf_1 		0.795 0.672
HLF
M04245_2.00 		Homo sapiens
NVTTRCRYAABN
NVTTRYGYAABN		 SELEX
Yin et al.(2017)
HLF_FL_HT-SELEX 		0.795 0.672
HLF
M04016_2.00 		Homo sapiens
RTKAYRTAAB
VTTAYRTMAY		 SELEX
Rodriguez-Martinez et al.(2017)
HLF.1 		0.795 0.672
HLF
M08786_2.00 		Homo sapiens
NRTTRYGTAAYMS
SKRTTACRYAAYN		 Misc
Kulakovskiy et al.(2013)
HLF_HUMAN.H11MO.0.C 		0.795 0.672
Hlf
M08815_2.00 		Mus musculus
VTTRTGYAABH
DVTTRCAYAAB		 Misc
Kulakovskiy et al.(2013)
HLF_MOUSE.H11MO.0.C 		0.795 0.672
HLF
M09937_2.00 		Homo sapiens
ATKRYGTAAY
RTTACRYMAT		 Transfac
Matys et al.(2006)
V$HLF_01 		0.795 0.672
HLF
M04246_2.00 		Homo sapiens
NVTTRCRYAABN
NVTTRYGYAABN		 SELEX
Yin et al.(2017)
HLF_FL_Methyl-HT-SELEX 		0.795 0.672
For this family, TFs with SR scores > 0.782 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0076490 bZIP 182 249
FBpp0076491 bZIP 202 269
FBpp0076492 bZIP 216 283
FBpp0076495 bZIP 579 643
FBpp0076497 bZIP 502 567
FBpp0289726 bZIP 163 227
FBpp0289727 bZIP 565 629
FBpp0297493 bZIP 202 269
FBpp0304390 bZIP 513 578
FBpp0304391 bZIP 207 274
FBpp0304392 bZIP 213 280
FBpp0304393 bZIP 196 263
FBpp0312154 bZIP 202 269

Links

Other bZIP family TFs
Other Drosophila melanogaster TFs

132 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
GL17823 Drosophila persimilis FBgn0155426 I 0.904
GI12193 Drosophila mojavensis FBgn0134950 I 0.904
GH23565 Drosophila grimshawi FBgn0131022 I 0.904
GM24985 Drosophila sechellia FBgn0179846 I 0.904
GD13032 Drosophila simulans FBgn0184754 I 0.904
GA28498 Drosophila pseudoobscura FBgn0249858 I 0.904
GE20386 Drosophila yakuba FBgn0237702 I 0.904
GK10510 Drosophila willistoni FBgn0212525 I 0.904
GJ11425 Drosophila virilis FBgn0198683 I 0.904
GG14935 Drosophila erecta FBgn0107189 I 0.904
LCUP014933 Lucilia cuprina LCUP014933 I 0.904
MDOA003519 Musca domestica MDOA003519 I 0.904
GF24150 Drosophila ananassae FBgn0101144 I 0.904
PPAI002842 Phlebotomus papatasi PPAI002842 I 0.887
LLOJ006612 Lutzomyia longipalpis LLOJ006612 I 0.887
AALB004300 Anopheles albimanus AALB004300 I 0.849
PDP1 Aedes aegypti AAEL005255 I 0.849
PDP1 Culex quinquefasciatus CPIJ014920 I 0.849
ASTEI09431 Anopheles stephensi ASTEI09431 I 0.849
ADAC004162 Anopheles darlingi ADAC004162 I 0.849
PDP1 Anopheles gambiae AGAP006376 I 0.849
AARA000887 Anopheles arabiensis AARA000887 I 0.849
CpipJ_CPIJ014920 Culex pipiens CpipJ_CPIJ014920 I 0.849
AEPI005427 Anopheles epiroticus AEPI005427 I 0.849
AMIN007990 Anopheles minimus AMIN007990 I 0.849
AFAF017409 Anopheles farauti AFAF017409 I 0.849
AFUN000141 Anopheles funestus AFUN000141 I 0.849
AQUA000938 Anopheles quadriannulatus AQUA000938 I 0.849
AMEM018156 Anopheles merus AMEM018156 I 0.849
ACOM039838 Anopheles coluzzii ACOM039838 I 0.849
ACUA004794 Anopheles culicifacies ACUA004794 I 0.849
ASIS001542 Anopheles sinensis ASIS001542 I 0.849
ADIR007438 Anopheles dirus ADIR007438 I 0.849
AATE006511 Anopheles atroparvus AATE006511 I 0.848
KGM_21614 Danaus plexippus KGM_21614 I 0.830
BGIBMGA003874 Bombyx mori BGIBMGA003874 I 0.830
HMEL011029 Heliconius melpomene HMEL011029 I 0.830
MCINX004280 Melitaea cinxia MCINX004280 I 0.830
Hsal_12188--XP_391997.2_APIME Harpegnathos saltator Hsal_12188--XP_391997.2_APIME I 0.829
NV13265 Nasonia vitripennis NV13265 I 0.828
GB43643 Apis mellifera GB43643 I 0.828
ACEP27179 Atta cephalotes ACEP27179 I 0.828
Cflo_03674--XP_391997.2_APIME Camponotus floridanus Cflo_03674--XP_391997.2_APIME I 0.828
SMAR002779 Strigamia maritima SMAR002779 I 0.826
ISCW004978 Ixodes scapularis ISCW004978 I 0.819
YQE_01842 Dendroctonus ponderosae YQE_01842 I 0.815
CGI_10008414 Crassostrea gigas CGI_10008414 I 0.809
ENSLOCG00000011595 Lepisosteus oculatus ENSLOCG00000011595 I 0.806
hlfa Oryzias latipes ENSORLG00000000969 I 0.803
Ogr00037 Ophisaurus gracilis Ogr00037 I 0.803
ENSPFOG00000018222 Poecilia formosa ENSPFOG00000018222 I 0.803
ENSONIG00000009563 Oreochromis niloticus ENSONIG00000009563 I 0.803
Alligator_sinensis_CCG020587.1 Alligator sinensis Alligator_sinensis_CCG020587.1 I 0.801
HLF Ornithorhynchus anatinus ENSOANG00000010288 I 0.801
ENSLACG00000012701 Latimeria chalumnae ENSLACG00000012701 I 0.800
CapteG151518 Capitella teleta CapteG151518 I 0.800
hlfb Takifugu rubripes ENSTRUG00000003909 I 0.799
ENSONIG00000019079 Oreochromis niloticus ENSONIG00000019079 I 0.799
hlfa Danio rerio ENSDARG00000074752 I 0.797
Myotis_brandtii_Hlf_10020713 Myotis brandtii Myotis_brandtii_Hlf_10020713 I 0.795
Pvit_00680 Pogona vitticeps Pvit_00680 I 0.795
Tal_R009182 Tyto alba Tal_R009182 I 0.795
ENSP00000226067 Macaca fascicularis ENSP00000226067 I 0.795
Afo_R002997 Aptenodytes forsteri Afo_R002997 I 0.795
Aan_R004902 Calypte anna Aan_R004902 I 0.795
Brh_R008067 Buceros rhinoceros Brh_R008067 I 0.795
Cmyd_10013489 Chelonia mydas Cmyd_10013489 I 0.795
ENSBTAP00000008682-D1 Bos grunniens ENSBTAP00000008682-D1 I 0.795
Gfo_R006518 Geospiza fortis Gfo_R006518 I 0.795
HLF Tupaia belangeri ENSTBEG00000006958 I 0.795
HLF Homo sapiens ENSG00000108924 D 0.795
HLF Gallus gallus ENSGALG00000003059 I 0.795
HLF Felis catus ENSFCAG00000022556 I 0.795
ENSFALG00000002265 Ficedula albicollis ENSFALG00000002265 I 0.795
HLF Echinops telfairi ENSETEG00000017670 I 0.795
HLF Gorilla gorilla ENSGGOG00000006075 I 0.795
HLF Loxodonta africana ENSLAFG00000016475 I 0.795
HLF Myotis lucifugus ENSMLUG00000007393 I 0.795
ENSMICG00000002860 Microcebus murinus ENSMICG00000002860 I 0.795
ENSMEUG00000016384 Macropus eugenii ENSMEUG00000016384 I 0.795
ENSLOCG00000012233 Lepisosteus oculatus ENSLOCG00000012233 I 0.795
HLF Erinaceus europaeus ENSEEUG00000010964 I 0.795
HLF Equus caballus ENSECAG00000016953 I 0.795
HLF Bos taurus ENSBTAG00000006618 I 0.795
ENSAPLG00000004386 Anas platyrhynchos ENSAPLG00000004386 I 0.795
ENSAMEG00000014714 Ailuropoda melanoleuca ENSAMEG00000014714 I 0.795
HLF Anolis carolinensis ENSACAG00000017417 I 0.795
HLF Canis familiaris ENSCAFG00000030851 I 0.795
ENSCHOG00000001396 Choloepus hoffmanni ENSCHOG00000001396 I 0.795
ENSDORG00000012644 Dipodomys ordii ENSDORG00000012644 I 0.795
ENSCSAG00000005557 Chlorocebus sabaeus ENSCSAG00000005557 I 0.795
ENSCPOG00000011000 Cavia porcellus ENSCPOG00000011000 I 0.795
HLF Callithrix jacchus ENSCJAG00000011298 I 0.795
HLF Macaca mulatta ENSMMUG00000022627 I 0.795
ENSLACG00000012726 Latimeria chalumnae ENSLACG00000012726 I 0.795
HLF Pan troglodytes ENSPTRG00000009424 I 0.795
HLF Pteropus vampyrus ENSPVAG00000007461 I 0.795
ENSPSIG00000016356 Pelodiscus sinensis ENSPSIG00000016356 I 0.795
HLF Monodelphis domestica ENSMODG00000014851 I 0.795
ENSPFOG00000004560 Poecilia formosa ENSPFOG00000004560 I 0.795
Hlf Rattus norvegicus ENSRNOG00000002456 I 0.795
ENSSARG00000013841 Sorex araneus ENSSARG00000013841 I 0.795
ENSTSYG00000009210 Tarsius syrichta ENSTSYG00000009210 I 0.795
HLF Tursiops truncatus ENSTTRG00000007194 I 0.795
HLF Taeniopygia guttata ENSTGUG00000009478 I 0.795
ENSSTOG00000029018 Ictidomys tridecemlineatus ENSSTOG00000029018 I 0.795
ENSSHAG00000015304 Sarcophilus harrisii ENSSHAG00000015304 I 0.795
ENSPANG00000022360 Papio anubis ENSPANG00000022360 I 0.795
ENSPPYG00000008257 Pongo abelii ENSPPYG00000008257 I 0.795
HLF Oryctolagus cuniculus ENSOCUG00000010547 I 0.795
Hlf Mus musculus ENSMUSG00000003949 D 0.795
ENSMPUG00000015400 Mustela putorius furo ENSMPUG00000015400 I 0.795
HLF Otolemur garnettii ENSOGAG00000007056 I 0.795
ENSNLEG00000007993 Nomascus leucogenys ENSNLEG00000007993 I 0.795
HLF Ochotona princeps ENSOPRG00000004195 I 0.795
ENSAMXG00000008798 Astyanax mexicanus ENSAMXG00000008798 I 0.794
ENSXMAG00000012903 Xiphophorus maculatus ENSXMAG00000012903 I 0.793
ENSGMOG00000004830 Gadus morhua ENSGMOG00000004830 I 0.792
PHUM426270 Pediculus humanus PHUM426270 I 0.791
e_gw.273.54.1 Branchiostoma floridae e_gw.273.54.1 I 0.791
e_gw.273.32.1 Branchiostoma floridae e_gw.273.32.1 I 0.791
ACYPI000702 Acyrthosiphon pisum ACYPI000702 I 0.789
CLEC008918 Cimex lectularius CLEC008918 I 0.788
hlfb Gasterosteus aculeatus ENSGACG00000010103 I 0.787
ENSXMAG00000016939 Xiphophorus maculatus ENSXMAG00000016939 I 0.786
ANCDUO_14303 Ancylostoma duodenale ANCDUO_14303 I 0.785
tefb Gasterosteus aculeatus ENSGACG00000007628 I 0.784
tefb Takifugu rubripes ENSTRUG00000003565 I 0.784
L596_g3194 Steinernema carpocapsae L596_g3194 I 0.783
L898_g30246 Steinernema monticolum L898_g30246 I 0.783
ENSAMXG00000015442 Astyanax mexicanus ENSAMXG00000015442 I 0.782