TF Information

SWI5 *(Saccharomyces cerevisiae)* C2H2 ZF
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source	Animal TF db
PF00096 (zf-C2H2)	IPR007087	YDR146C	T131829_2.00	Ensembl (2018-Dec-8)	Link out
NCBI Gene Info: Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and mediator complex binding activity. Involved in positive regulation of mating type switching; positive regulation of transcription involved in exit from mitosis, from RNA polymerase II promoter; and regulation of transcription involved in G1/S transition of mitotic cell cycle. Located in cytoplasm and nucleus. Orthologous to human KLF10 (Kruppel like factor 10). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
SWI5 M00020_2.00	Saccharomyces cerevisiae	NNKGCTGGTHN	NDACCAGCMNN	PBM Badis et al.(2008) SWI5_2037	(Direct)	(Direct)
SWI5 M07450_2.00	Saccharomyces cerevisiae	KGCTGGKH	DMCCAGCM	PBM, CSA and or DIP-chip Mathelier et al.(2014) MA0402.1	(Direct)	(Direct)
SWI5 M08516_2.00	Saccharomyces cerevisiae	KGCTGGKH	DMCCAGCM	Misc DeBoer et al.(2011) YDR146C_569	(Direct)	(Direct)
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
ACE2 M00033_2.00	Saccharomyces cerevisiae	NTGCTGGBYN	NRVCCAGCAN	PBM Badis et al.(2008) ACE2_2082	0.797	0.889
ACE2 M07463_2.00	Saccharomyces cerevisiae	NGCTGGB	VCCAGCN	PBM, CSA and or DIP-chip Mathelier et al.(2014) MA0267.1	0.797	0.889
ACE2 M08534_2.00	Saccharomyces cerevisiae	NGCTGGBH	DVCCAGCN	Misc DeBoer et al.(2011) YLR131C_1332	0.797	0.889
For this family, TFs with SR scores > 0.755* will likely have a similar motif*

Experimental Constructs

Motif ID	Domain	From	To	Sequence
M00020_2.00	C2H2 ZF	51	75	FECLFPGCTKTFKRRYNIRSHIQTH
M00020_2.00	C2H2 ZF	81	105	YSCDHPGCDKAFVRNHDLIRHKKSH
M00020_2.00	C2H2 ZF	114	130	CGKKFNREDALVVHRSR

DNA Binding Domains

Protein ID	Domain	From	To	Sequence
YDR146C	C2H2 ZF	550	574	FECLFPGCTKTFKRRYNIRSHIQTH
YDR146C	C2H2 ZF	580	604	YSCDHPGCDKAFVRNHDLIRHKKSH
YDR146C	C2H2 ZF	613	629	CGKKFNREDALVVHRSR

Links
Other C2H2 ZF family TFs
Other *Saccharomyces cerevisiae* TFs

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18 Related TFs

Name	Species	Gene ID	Motif Evidence	SR Score	Action