ENSP00000301727 (Macaca fascicularis)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00096 (zf-C2H2) IPR007087 ENSP00000301727 T135025_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
The zinc finger protein encoded by this gene is one of several cellular transcription factors whose DNA-binding activities are regulated through the action of adenovirus E1A. A 50-kDa amino-terminal product is generated from the full-length protein through proteolytic cleavage. The protein is differentially regulated by E1A-induced phosphorylation. The full-length gene product represses transcription from the E4 promoter in the absence of E1A, while the 50-kDa form acts as a transcriptional activator in its presence. Alternative splicing results in multiple transcripts encoding different proteins. [provided by RefSeq, Jan 2014]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
E4F1
M10255_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E4F1_Q6_01 		0.825 0.990
E4F1
M10256_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$E4F1_Q6 		0.825 0.990
E4f1
M10339_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$PHIAP3_03 		0.817 0.971
For this family, TFs with SR scores > 0.755 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000301727 C2H2 ZF 140 162
ENSP00000301727 C2H2 ZF 168 190
ENSP00000301727 C2H2 ZF 196 217
ENSP00000301727 C2H2 ZF 383 405
ENSP00000301727 C2H2 ZF 411 433
ENSP00000301727 C2H2 ZF 439 461
ENSP00000301727 C2H2 ZF 467 489
ENSP00000301727 C2H2 ZF 495 517
ENSP00000301727 C2H2 ZF 523 544

Links

Other C2H2 ZF family TFs
Other Macaca fascicularis TFs

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30 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action