CG43689 (Drosophila melanogaster)
C2HC ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF01530 (zf-C2HC) IPR002515 FBgn0263772 T159342_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 39. Orthologous to human ST18 (ST18 C2H2C-type zinc finger transcription factor); MYT1 (myelin transcription factor 1); and MYT1L (myelin transcription factor 1 like). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ztf-11
M00650_2.00 		Caenorhabditis elegans
VAAGTTTN
NAAACTTB		 PBM
Narasimhan et al.(2015)
pTH9925 		0.707 0.707
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0302629 C2HC ZF 1108 1136
FBpp0302629 C2HC ZF 1153 1181
FBpp0302630 C2HC ZF 415 443
FBpp0302630 C2HC ZF 1166 1194
FBpp0302630 C2HC ZF 1211 1239
FBpp0302631 C2HC ZF 409 432
FBpp0302631 C2HC ZF 438 466
FBpp0302631 C2HC ZF 1189 1217
FBpp0302631 C2HC ZF 1234 1262
FBpp0302632 C2HC ZF 1108 1136
FBpp0302632 C2HC ZF 1153 1181
FBpp0302633 C2HC ZF 415 443
FBpp0302633 C2HC ZF 1166 1194
FBpp0302633 C2HC ZF 1211 1239
FBpp0308738 C2HC ZF 1078 1106
FBpp0308738 C2HC ZF 1123 1151

Links

Other C2HC ZF family TFs
Other Drosophila melanogaster TFs

117 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
GJ17015 Drosophila virilis FBgn0204192 N 1.000
GE16325 Drosophila yakuba FBgn0233857 N 1.000
GM12320 Drosophila sechellia FBgn0167257 N 1.000
GL14771 Drosophila persimilis FBgn0152375 I 1.000
GH24141 Drosophila grimshawi FBgn0131597 N 1.000
GI16394 Drosophila mojavensis FBgn0139142 I 1.000
GA24131 Drosophila pseudoobscura FBgn0245530 N 1.000
LCUP002242 Lucilia cuprina LCUP002242 I 1.000
GF20773 Drosophila ananassae FBgn0097779 N 0.989
MDOA006645 Musca domestica MDOA006645 N 0.989
AMAM009924 Anopheles maculatus AMAM009924 I 0.983
ACOM027979 Anopheles coluzzii ACOM027979 I 0.983
HHAL001110-PA Halyomorpha halys HHAL001110-PA I 0.983
AFAF001557 Anopheles farauti AFAF001557 I 0.983
AATE018011 Anopheles atroparvus AATE018011 I 0.983
ACYPI31512 Acyrthosiphon pisum ACYPI31512 I 0.983
GK10260 Drosophila willistoni FBgn0212275 N 0.977
CpipJ_CPIJ011292 Culex pipiens CpipJ_CPIJ011292 N 0.920
CPIJ011292 Culex quinquefasciatus CPIJ011292 N 0.920
AMEM010335 Anopheles merus AMEM010335 N 0.920
nRc.2.0.1.g21954 Romanomermis culicivorax nRc.2.0.1.g21954 N 0.879
AARA002561 Anopheles arabiensis AARA002561 N 0.874
AGAP000875 Anopheles gambiae AGAP000875 N 0.874
ACUA023712 Anopheles culicifacies ACUA023712 N 0.874
AMEC011182 Anopheles melas AMEC011182 N 0.874
ASTEI01189 Anopheles stephensi ASTEI01189 N 0.874
ASIS023610 Anopheles sinensis ASIS023610 N 0.874
AQUA002448 Anopheles quadriannulatus AQUA002448 N 0.874
AMIN005800 Anopheles minimus AMIN005800 N 0.874
ADIR004650 Anopheles dirus ADIR004650 N 0.874
AFUN000252 Anopheles funestus AFUN000252 N 0.874
AAEL001230 Aedes aegypti AAEL001230 N 0.865
ACEP14857 Atta cephalotes ACEP14857 I 0.862
YQE_11977 Dendroctonus ponderosae YQE_11977 I 0.845
ADAC002899 Anopheles darlingi ADAC002899 N 0.845
AMAM005266 Anopheles maculatus AMAM005266 N 0.845
LDEC007508 Leptinotarsa decemlineata LDEC007508 N 0.820
Ocbimv22028296m.g Octopus bimaculoides Ocbimv22028296m.g N 0.793
MCINX013435 Melitaea cinxia MCINX013435 N 0.791
SMU15021651 Schmidtea mediterranea SMU15021651 N 0.776
ACHR008455 Anopheles christyi ACHR008455 N 0.766
ENSGMOG00000000679 Gadus morhua ENSGMOG00000000679 N 0.766
BGLB002715 Biomphalaria glabrata BGLB002715 N 0.759
Cmyd_10017545 Chelonia mydas Cmyd_10017545 N 0.747
BGIBMGA006961 Bombyx mori BGIBMGA006961 N 0.747
CPIJ018573 Culex quinquefasciatus CPIJ018573 N 0.741
CpipJ_CPIJ018573 Culex pipiens CpipJ_CPIJ018573 N 0.741
Ocbimv22028295m.g Octopus bimaculoides Ocbimv22028295m.g I 0.740
ISCW018799 Ixodes scapularis ISCW018799 I 0.737
D918_01045 Trichuris suis D918_01045 N 0.730
AALB006664 Anopheles albimanus AALB006664 N 0.724
ECANG7_03405 Echinococcus canadensis ECANG7_03405 N 0.724
MYT1L Homo sapiens ENSG00000186487 I 0.724
HDID_0000016901 Hymenolepis diminuta HDID_0000016901 N 0.724
AEPI011200 Anopheles epiroticus AEPI011200 N 0.724
TC004325 Tribolium castaneum TC004325 N 0.724
SMU15028607 Schmidtea mediterranea SMU15028607 I 0.724
SPU_002689 Strongylocentrotus purpuratus SPU_002689 N 0.724
CLEC010165 Cimex lectularius CLEC010165 N 0.724
CJA03417 Caenorhabditis japonica CJA03417 I 0.724
ENSMEUG00000001386 Macropus eugenii ENSMEUG00000001386 N 0.722
ST18 Callithrix jacchus ENSCJAG00000014630 N 0.722
TMUE_s0020007600 Trichuris muris TMUE_s0020007600 N 0.721
nDi.2.2.2.g06992 Dirofilaria immitis nDi.2.2.2.g06992 I 0.719
CBN18838 Caenorhabditis brenneri CBN18838 I 0.719
EVEC_0001307101 Enterobius vermicularis EVEC_0001307101 I 0.719
CBN09920 Caenorhabditis brenneri CBN09920 I 0.719
D917_04267 Trichinella nativa D917_04267 N 0.719
CBG03854 Caenorhabditis briggsae CBG03854 I 0.719
RSKR_0000214800 Rhabditophanes kr3021 RSKR_0000214800 I 0.719
nLs.2.1.2.g09672 Litomosoides sigmodontis nLs.2.1.2.g09672 I 0.719
ztf-11 Caenorhabditis elegans WBGene00009939 D 0.719
L596_g1281 Steinernema carpocapsae L596_g1281 I 0.719
L889_g28085 Steinernema feltiae L889_g28085 I 0.719
WBGene00238210 Onchocerca volvulus WBGene00238210 I 0.719
CRE08084 Caenorhabditis remanei CRE08084 I 0.719
Hba_17025 Heterorhabditis bacteriophora Hba_17025 I 0.719
SMUV_0000666101 Syphacia muris SMUV_0000666101 I 0.719
ENSXMAG00000007322 Xiphophorus maculatus ENSXMAG00000007322 N 0.712
ci-mytf Ciona intestinalis ENSCING00000007794 N 0.712
NECAME_10938 Necator americanus NECAME_10938 I 0.707
NBR_0001165301 Nippostrongylus brasiliensis NBR_0001165301 I 0.707
SBAD_0000885801 Soboliphyme baturini SBAD_0000885801 N 0.707
SPAL_0000892700 Strongyloides papillosus SPAL_0000892700 I 0.707
SSLN_0001285301 Schistocephalus solidus SSLN_0001285301 N 0.707
SSTP_0000574400 Strongyloides stercoralis SSTP_0000574400 I 0.707
SVE_1935100 Strongyloides venezuelensis SVE_1935100 I 0.707
TASK_0000444001 Taenia asiatica TASK_0000444001 N 0.707
TELCIR_26151 Teladorsagia circumcincta TELCIR_26151 I 0.707
PTRK_0001788400 Parastrongyloides trichosuri PTRK_0001788400 I 0.707
MCOS_0000008701 Mesocestoides corti MCOS_0000008701 N 0.707
TTAC_0000856801 Hydatigera taeniaeformis TTAC_0000856801 N 0.707
TELCIR_22038 Teladorsagia circumcincta TELCIR_22038 I 0.707
OESDEN_24201 Oesophagostomum dentatum OESDEN_24201 I 0.707
MYT1 Erinaceus europaeus ENSEEUG00000004157 N 0.707
Minc05804 Meloidogyne incognita Minc05804 I 0.707
MYT1L Macaca mulatta ENSMMUG00000009310 I 0.707
AMAM003778 Anopheles maculatus AMAM003778 I 0.707
ENSBTAG00000003540 Bos taurus ENSBTAG00000003540 I 0.707
AFAF020264 Anopheles farauti AFAF020264 I 0.707
ACAC_0000050701 Angiostrongylus cantonensis ACAC_0000050701 I 0.707
ACOC_0000924001 Angiostrongylus costaricensis ACOC_0000924001 I 0.707
DICVIV_01967 Dictyocaulus viviparus DICVIV_01967 I 0.707
EmuJ_000598400 Echinococcus multilocularis EmuJ_000598400 N 0.707
Cmyd_10014184 Chelonia mydas Cmyd_10014184 I 0.707
ASU_06642 Ascaris suum ASU_06642 I 0.707
ANCCEY_04739 Ancylostoma ceylanicum ANCCEY_04739 I 0.707
ANCDUO_13968 Ancylostoma duodenale ANCDUO_13968 I 0.707
ENSPMAG00000002519 Petromyzon marinus ENSPMAG00000002519 N 0.705
MYT1L Pteropus vampyrus ENSPVAG00000001625 N 0.703
SPAL_0000489100 Strongyloides papillosus SPAL_0000489100 I 0.702
BXY_0842900 Bursaphelenchus xylophilus BXY_0842900 I 0.702
SVE_1952800 Strongyloides venezuelensis SVE_1952800 I 0.702
L893_g1446 Steinernema glaseri L893_g1446 I 0.702
MYT1L Choloepus hoffmanni ENSCHOG00000002551 N 0.701
HelroG85268 Helobdella robusta HelroG85268 I 0.700