ztf-11 (Caenorhabditis elegans)
C2HC ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF01530 (zf-C2HC) IPR002515 WBGene00009939 T159400_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable zinc ion binding activity. Involved in nematode larval development; neuron differentiation; and positive regulation of cell differentiation. Located in nucleus. Is expressed in g1 and head neurons. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 39. Orthologous to human ST18 (ST18 C2H2C-type zinc finger transcription factor); MYT1 (myelin transcription factor 1); and MYT1L (myelin transcription factor 1 like). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ztf-11
M00650_2.00		 Caenorhabditis elegans
VAAGTTTN
NAAACTTB		 PBM
Narasimhan et al.(2015)
pTH9925		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.700 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00650_2.00 C2HC ZF 53 80
M00650_2.00 C2HC ZF 99 127

DNA Binding Domains

Protein ID Domain From To Sequence
F52F12.6a C2HC ZF 264 291
F52F12.6a C2HC ZF 310 338
F52F12.6b C2HC ZF 167 194
F52F12.6b C2HC ZF 213 241

Links

Other C2HC ZF family TFs
Other Caenorhabditis elegans TFs

63 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CBN09920 Caenorhabditis brenneri CBN09920 I 1.000
CBG03854 Caenorhabditis briggsae CBG03854 I 1.000
CRE08084 Caenorhabditis remanei CRE08084 I 1.000
CBN18838 Caenorhabditis brenneri CBN18838 I 1.000
CJA03417 Caenorhabditis japonica CJA03417 I 0.982
NECAME_10938 Necator americanus NECAME_10938 I 0.947
ANCDUO_13968 Ancylostoma duodenale ANCDUO_13968 I 0.947
ANCCEY_04739 Ancylostoma ceylanicum ANCCEY_04739 I 0.947
ACOC_0000924001 Angiostrongylus costaricensis ACOC_0000924001 I 0.947
OESDEN_24201 Oesophagostomum dentatum OESDEN_24201 I 0.947
ACAC_0000050701 Angiostrongylus cantonensis ACAC_0000050701 I 0.947
ASU_06642 Ascaris suum ASU_06642 I 0.947
TELCIR_22038 Teladorsagia circumcincta TELCIR_22038 I 0.947
TELCIR_26151 Teladorsagia circumcincta TELCIR_26151 I 0.947
NBR_0001165301 Nippostrongylus brasiliensis NBR_0001165301 I 0.947
DICVIV_01967 Dictyocaulus viviparus DICVIV_01967 I 0.947
SMUV_0000666101 Syphacia muris SMUV_0000666101 I 0.930
nDi.2.2.2.g06992 Dirofilaria immitis nDi.2.2.2.g06992 I 0.930
WBGene00238210 Onchocerca volvulus WBGene00238210 I 0.930
Hba_17025 Heterorhabditis bacteriophora Hba_17025 I 0.930
RSKR_0000214800 Rhabditophanes kr3021 RSKR_0000214800 I 0.930
nLs.2.1.2.g09672 Litomosoides sigmodontis nLs.2.1.2.g09672 I 0.930
EVEC_0001307101 Enterobius vermicularis EVEC_0001307101 I 0.930
L889_g28085 Steinernema feltiae L889_g28085 I 0.912
PTRK_0001788400 Parastrongyloides trichosuri PTRK_0001788400 I 0.912
L596_g1281 Steinernema carpocapsae L596_g1281 I 0.912
SPAL_0000892700 Strongyloides papillosus SPAL_0000892700 I 0.912
SVE_1935100 Strongyloides venezuelensis SVE_1935100 I 0.912
SSTP_0000574400 Strongyloides stercoralis SSTP_0000574400 I 0.912
L893_g1446 Steinernema glaseri L893_g1446 I 0.895
BXY_0842900 Bursaphelenchus xylophilus BXY_0842900 I 0.860
SPAL_0000489100 Strongyloides papillosus SPAL_0000489100 I 0.860
SVE_1952800 Strongyloides venezuelensis SVE_1952800 I 0.860
SMU15028607 Schmidtea mediterranea SMU15028607 I 0.842
Minc05804 Meloidogyne incognita Minc05804 I 0.842
ENSBTAG00000003540 Bos taurus ENSBTAG00000003540 I 0.789
MYT1L Macaca mulatta ENSMMUG00000009310 I 0.789
ISCW018799 Ixodes scapularis ISCW018799 I 0.789
Cmyd_10014184 Chelonia mydas Cmyd_10014184 I 0.789
MYT1L Homo sapiens ENSG00000186487 I 0.789
ENSLACG00000008399 Latimeria chalumnae ENSLACG00000008399 I 0.772
ST18 Homo sapiens ENSG00000147488 I 0.754
ENSAMEG00000015014 Ailuropoda melanoleuca ENSAMEG00000015014 I 0.754
ENSTGUG00000014218 Taeniopygia guttata ENSTGUG00000014218 I 0.754
ACEP14857 Atta cephalotes ACEP14857 I 0.754
ACYPI31510 Acyrthosiphon pisum ACYPI31510 I 0.737
AFAF020264 Anopheles farauti AFAF020264 I 0.737
AMAM003778 Anopheles maculatus AMAM003778 I 0.737
ACOM027979 Anopheles coluzzii ACOM027979 I 0.719
CG43689 Drosophila melanogaster FBgn0263772 I 0.719
YQE_11977 Dendroctonus ponderosae YQE_11977 I 0.719
GL14771 Drosophila persimilis FBgn0152375 I 0.719
GI16394 Drosophila mojavensis FBgn0139142 I 0.719
ACYPI31512 Acyrthosiphon pisum ACYPI31512 I 0.719
AMAM009924 Anopheles maculatus AMAM009924 I 0.719
HHAL001110-PA Halyomorpha halys HHAL001110-PA I 0.719
AFAF001557 Anopheles farauti AFAF001557 I 0.719
LCUP002242 Lucilia cuprina LCUP002242 I 0.719
AATE018011 Anopheles atroparvus AATE018011 I 0.719
SMU15021651 Schmidtea mediterranea SMU15021651 N 0.702
Ocbimv22028296m.g Octopus bimaculoides Ocbimv22028296m.g N 0.702
AATE000335 Anopheles atroparvus AATE000335 I 0.702