HHAL001434-PA (Halyomorpha halys)
CSD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00313 (CSD) IPR002059 HHAL001434-PA T165508_2.00 Misc (2018-Jan-19)
NCBI Gene Info:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
YBX1
M04661_2.00
Homo sapiens
GRTGGWACR

YGTWCCAYC
SELEX
Yin et al.(2017)
YBX1_eDBD_HT-SELEX
0.838 0.838
YBX1
M10411_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$YB1_Q3
0.838 0.838
YBX1
M10412_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$YB1_Q4
0.838 0.838
YBX1
M04662_2.00
Homo sapiens
GRTGKDRCD

HGYHMCAYC
SELEX
Yin et al.(2017)
YBX1_eDBD_Methyl-HT-SELEX
0.838 0.838
NEMVEDRAFT_v1g104083
M01207_2.00
Nematostella vectensis
NNNDDHRN

NYDHHNNN
PBM
Lambert et al.(2019)
pTH9768
0.730 0.730
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
HHAL001434-PA CSD 23 63

Links

Other CSD family TFs
Other Halyomorpha halys TFs

24 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
Alligator_sinensis_CCG014301.1 Alligator sinensis Alligator_sinensis_CCG014301.1 I 0.795
CapteG121832 Capitella teleta CapteG121832 I 0.765
CapteG58124 Capitella teleta CapteG58124 I 0.784
CLEC013418 Cimex lectularius CLEC013418 I 0.745
Cmyd_10000339 Chelonia mydas Cmyd_10000339 I 0.811
Cmyd_10002115 Chelonia mydas Cmyd_10002115 I 0.861
Cmyd_10003103 Chelonia mydas Cmyd_10003103 I 0.838
CPIJ002248 Culex quinquefasciatus CPIJ002248 I 0.811
CpipJ_CPIJ002248 Culex pipiens CpipJ_CPIJ002248 I 0.811
ENSGGOG00000023840 Gorilla gorilla ENSGGOG00000023840 I 0.743
ENSMLUG00000024638 Myotis lucifugus ENSMLUG00000024638 I 0.707
ENSMLUG00000029452 Myotis lucifugus ENSMLUG00000029452 I 0.775
ENSMPUG00000013922 Mustela putorius furo ENSMPUG00000013922 I 0.838
ENSOCUG00000000147 Oryctolagus cuniculus ENSOCUG00000000147 I 0.824
ENSOCUG00000021258 Oryctolagus cuniculus ENSOCUG00000021258 I 0.756
ENSOCUG00000024588 Oryctolagus cuniculus ENSOCUG00000024588 I 0.775
ENSOCUG00000026608 Oryctolagus cuniculus ENSOCUG00000026608 I 0.725
ENSOGAG00000030360 Otolemur garnettii ENSOGAG00000030360 I 0.703
ENSOGAG00000031268 Otolemur garnettii ENSOGAG00000031268 I 0.703
ENSSHAG00000011350 Sarcophilus harrisii ENSSHAG00000011350 I 0.714
Sakowv30002198m.g Saccoglossus kowalevskii Sakowv30002198m.g I 0.865
SINV21160 Solenopsis invicta SINV21160 I 0.702
Tal_R003478 Tyto alba Tal_R003478 I 0.865
YBX1 Loxodonta africana ENSLAFG00000031170 I 0.744