DUXA (Homo sapiens)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSG00000258873 T209954_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This gene is a member of the DUXA homeobox gene family. Evidence of mRNA expression has not yet been found for this gene. Multiple, related processed pseudogenes have been found which are thought to reflect expression of this gene in the germ line or embryonic cells. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
DUXA
M01247_2.00
Homo sapiens
NTGATTRNN

NNYAATCAN
PBM
Lambert et al.(2019)
pTH11226
(Direct) (Direct)
DUXA
M03244_2.00
Homo sapiens
NHRAYBYAATCAN

NTGATTRVRTYDN
SELEX
Jolma et al.(2013)
DUXA_1
(Direct) (Direct)
DUXA
M05402_2.00
Homo sapiens
TRAYBYAATCA

TGATTRVRTYA
SELEX
Yin et al.(2017)
DUXA_eDBD_HT-SELEX
(Direct) (Direct)
DUXA
M05403_2.00
Homo sapiens
YRAYBYAATCA

TGATTRVRTYR
SELEX
Yin et al.(2017)
DUXA_eDBD_Methyl-HT-SELEX
(Direct) (Direct)
DUXA
M10756_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$DUXA_02
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
For this family, TFs with SR scores > 0.599 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M01247_2.00 Homeodomain 16 70
M01247_2.00 Homeodomain 102 156

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000452398 Homeodomain 16 70
ENSP00000452398 Homeodomain 102 156

Links

Other Homeodomain family TFs
Other Homo sapiens TFs

30 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ENSPPYG00000010457 Pongo abelii ENSPPYG00000010457 I 0.867
DUXA Gorilla gorilla ENSGGOG00000005650 I 0.867
DUXA Pan troglodytes ENSPTRG00000028871 I 0.867
ENSMMUP00000010232 Macaca fascicularis ENSMMUP00000010232 I 0.841
DUXA Macaca mulatta ENSMMUG00000007788 I 0.841
ENSCSAG00000001657 Chlorocebus sabaeus ENSCSAG00000001657 I 0.841
ENSPANG00000009357 Papio anubis ENSPANG00000009357 I 0.841
DUXA Equus caballus ENSECAG00000021112 I 0.833
ENSOARG00000003446 Ovis aries ENSOARG00000003446 I 0.827
DUXA Tursiops truncatus ENSTTRG00000014200 I 0.818
DUXA Microcebus murinus ENSMICG00000006042 I 0.816
DUXA Felis catus ENSFCAG00000007545 I 0.816
ENSAMEG00000004960 Ailuropoda melanoleuca ENSAMEG00000004960 I 0.814
ENSDNOG00000025505 Dasypus novemcinctus ENSDNOG00000025505 I 0.813
ENSDNOG00000046863 Dasypus novemcinctus ENSDNOG00000046863 I 0.811
DUXA Canis familiaris ENSCAFG00000002431 I 0.811
DUXA Loxodonta africana ENSLAFG00000030167 I 0.787
ENSBTAP00000049813-D1 Bos grunniens ENSBTAP00000049813-D1 I 0.785
DUXA Oryctolagus cuniculus ENSOCUG00000011331 I 0.779
ENSCJAG00000021948 Callithrix jacchus ENSCJAG00000021948 I 0.743
ENSCJAG00000031259 Callithrix jacchus ENSCJAG00000031259 I 0.743
ENSCJAG00000032154 Callithrix jacchus ENSCJAG00000032154 I 0.743
NEMVEDRAFT_v1g38792 Nematostella vectensis NEMVEDRAFT_v1g38792 I 0.659
NEMVEDRAFT_v1g92436 Nematostella vectensis NEMVEDRAFT_v1g92436 I 0.643
NEMVEDRAFT_v1g92500 Nematostella vectensis NEMVEDRAFT_v1g92500 I 0.643
ENSNLEG00000010886 Nomascus leucogenys ENSNLEG00000010886 I 0.624
ENSMICG00000006881 Microcebus murinus ENSMICG00000006881 I 0.616
ENSMICG00000015060 Microcebus murinus ENSMICG00000015060 I 0.616
ENSDNOG00000049160 Dasypus novemcinctus ENSDNOG00000049160 I 0.616
ACOM031533 Anopheles coluzzii ACOM031533 I 0.605