Myrf (Mus musculus)
Ndt80/PhoG

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF05224 (NDT80_PhoG) IPR007888 ENSMUSG00000036098 T299792_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including central nervous system myelin maintenance; positive regulation of myelination; and regulation of transcription, DNA-templated. Located in endoplasmic reticulum membrane and nucleus. Is expressed in pigmented retinal epithelium; spinal cord; and spinal cord marginal layer. Orthologous to human MYRF (myelin regulatory factor). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Myrf
M02386_2.00		 Mus musculus
NNGTRHSNNN
NNNSDYACNN		 PBM
Weirauch et al.(2014)
pTH8554		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
MYRF
M02385_2.00 		Homo sapiens
TGGTACCA
TGGTACCA		 PBM
Weirauch et al.(2014)
pTH9310 		1.000 1.000
myrf
M02384_2.00 		Danio rerio
TGGTACCR
YGGTACCA		 PBM
Weirauch et al.(2014)
pTH8654 		0.825 0.825
For this family, TFs with SR scores > 0.700 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M02386_2.00 Ndt80/PhoG 51 198

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000085329 Ndt80/PhoG 393 540
ENSMUSP00000139601 Ndt80/PhoG 393 540
ENSMUSP00000140871 Ndt80/PhoG 191 338

Links

Other Ndt80/PhoG family TFs
Other Mus musculus TFs

62 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
MYRF Sus scrofa ENSSSCG00000013078 I 1.000
MYRF Gorilla gorilla ENSGGOG00000012529 I 1.000
MYRF Pan troglodytes ENSPTRG00000003749 I 1.000
MYRF Pteropus vampyrus ENSPVAG00000012342 I 1.000
Myrf Rattus norvegicus ENSRNOG00000028274 I 1.000
MYRF Canis familiaris ENSCAFG00000016062 I 1.000
ENSAMEG00000016669 Ailuropoda melanoleuca ENSAMEG00000016669 I 1.000
MYRF Homo sapiens ENSG00000124920 D 1.000
MYRF Felis catus ENSFCAG00000013683 I 1.000
Myrf Dipodomys ordii ENSDORG00000002029 I 1.000
ENSPANG00000013413 Papio anubis ENSPANG00000013413 I 0.993
ENSMPUG00000014126 Mustela putorius furo ENSMPUG00000014126 I 0.993
MYRF Macaca mulatta ENSMMUG00000006655 I 0.993
MYRF Otolemur garnettii ENSOGAG00000010786 I 0.993
ENSPPYG00000003180 Pongo abelii ENSPPYG00000003180 I 0.993
ENSSTOG00000000529 Ictidomys tridecemlineatus ENSSTOG00000000529 I 0.993
MYRF Callithrix jacchus ENSCJAG00000019218 I 0.993
MYRF Oryctolagus cuniculus ENSOCUG00000003269 I 0.993
ENSCSAG00000006452 Chlorocebus sabaeus ENSCSAG00000006452 I 0.993
MYRF Bos taurus ENSBTAG00000006990 I 0.986
MYRF Dasypus novemcinctus ENSDNOG00000005294 I 0.986
MYRF Cavia porcellus ENSCPOG00000013543 I 0.979
Alligator_sinensis_CCG012901.1 Alligator sinensis Alligator_sinensis_CCG012901.1 I 0.965
ENSBTAP00000009187-D1 Bos grunniens ENSBTAP00000009187-D1 I 0.958
MYRF Equus caballus ENSECAG00000021799 I 0.958
ENSP00000278836 Macaca fascicularis ENSP00000278836 I 0.951
MYRF Procavia capensis ENSPCAG00000017079 I 0.930
ENSOARG00000013482 Ovis aries ENSOARG00000013482 I 0.930
MYRF Myotis lucifugus ENSMLUG00000010326 I 0.930
ENSPSIG00000015590 Pelodiscus sinensis ENSPSIG00000015590 I 0.923
ENSFALG00000011806 Ficedula albicollis ENSFALG00000011806 I 0.916
ENSTGUG00000006600 Taeniopygia guttata ENSTGUG00000006600 I 0.916
Gfo_R011942 Geospiza fortis Gfo_R011942 I 0.916
ENSAPLG00000006054 Anas platyrhynchos ENSAPLG00000006054 I 0.916
MYRF Meleagris gallopavo ENSMGAG00000004733 I 0.916
ENSGALG00000020522 Gallus gallus ENSGALG00000020522 I 0.916
ENSSHAG00000002443 Sarcophilus harrisii ENSSHAG00000002443 I 0.888
Brh_R007745 Buceros rhinoceros Brh_R007745 I 0.888
Aan_R010750 Calypte anna Aan_R010750 I 0.887
Afo_R010549 Aptenodytes forsteri Afo_R010549 I 0.887
Tal_R006175 Tyto alba Tal_R006175 I 0.887
ENSLACG00000016455 Latimeria chalumnae ENSLACG00000016455 I 0.874
Pvit_15884 Pogona vitticeps Pvit_15884 I 0.874
ENSMEUG00000004200 Macropus eugenii ENSMEUG00000004200 I 0.860
ENSNLEG00000003069 Nomascus leucogenys ENSNLEG00000003069 I 0.846
myrf Xenopus tropicalis XB-GENE-1020968 I 0.839
ENSAMXG00000015793 Astyanax mexicanus ENSAMXG00000015793 I 0.839
ENSXMAG00000003748 Xiphophorus maculatus ENSXMAG00000003748 I 0.832
ENSGMOG00000017696 Gadus morhua ENSGMOG00000017696 I 0.832
MYRF Anolis carolinensis ENSACAG00000017691 I 0.825
ENSPFOG00000011050 Poecilia formosa ENSPFOG00000011050 I 0.825
myrf Danio rerio ENSDARG00000078676 D 0.825
MYRF Oryzias latipes ENSORLG00000006459 I 0.818
MYRF Takifugu rubripes ENSTRUG00000005197 I 0.811
ENSONIG00000015523 Oreochromis niloticus ENSONIG00000015523 I 0.811
myrf.L Xenopus laevis XB-GENE-1020972 I 0.811
myrf Gasterosteus aculeatus ENSGACG00000005416 I 0.804
MYRF Tetraodon nigroviridis ENSTNIG00000016074 I 0.797
ENSMMUG00000006501 Macaca mulatta ENSMMUG00000006501 I 0.722
ENSOARG00000020232 Ovis aries ENSOARG00000020232 I 0.706
Ogr07579 Ophisaurus gracilis Ogr07579 N 0.706