myrf (Danio rerio)
Ndt80/PhoG

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF05224 (NDT80_PhoG) IPR007888 ENSDARG00000078676 T299754_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity and sequence-specific DNA binding activity. Predicted to be involved in central nervous system myelin maintenance; positive regulation of transcription, DNA-templated; and protein autoprocessing. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum membrane and nucleus. Used to study eye disease. Orthologous to human MYRF (myelin regulatory factor). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
myrf
M02384_2.00		 Danio rerio
TGGTACCR
YGGTACCA		 PBM
Weirauch et al.(2014)
pTH8654		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
MYRF
M02385_2.00 		Homo sapiens
TGGTACCA
TGGTACCA		 PBM
Weirauch et al.(2014)
pTH9310 		0.825 0.825
Myrf
M02386_2.00 		Mus musculus
NNGTRHSNNN
NNNSDYACNN		 PBM
Weirauch et al.(2014)
pTH8554 		0.825 0.825
For this family, TFs with SR scores > 0.700 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M02384_2.00 Ndt80/PhoG 51 198

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000104600 Ndt80/PhoG 322 469
ENSDARP00000127515 Ndt80/PhoG 322 469

Links

Other Ndt80/PhoG family TFs
Other Danio rerio TFs

65 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSAMXG00000015793 Astyanax mexicanus ENSAMXG00000015793 I 0.944
ENSGMOG00000017696 Gadus morhua ENSGMOG00000017696 I 0.937
ENSXMAG00000003748 Xiphophorus maculatus ENSXMAG00000003748 I 0.923
ENSPFOG00000011050 Poecilia formosa ENSPFOG00000011050 I 0.916
ENSLOCG00000000407 Lepisosteus oculatus ENSLOCG00000000407 I 0.915
ENSONIG00000015523 Oreochromis niloticus ENSONIG00000015523 I 0.909
myrf Gasterosteus aculeatus ENSGACG00000005416 I 0.909
MYRF Oryzias latipes ENSORLG00000006459 I 0.909
MYRF Tetraodon nigroviridis ENSTNIG00000016074 I 0.895
MYRF Takifugu rubripes ENSTRUG00000005197 I 0.895
ENSLACG00000016455 Latimeria chalumnae ENSLACG00000016455 I 0.874
ENSPSIG00000015590 Pelodiscus sinensis ENSPSIG00000015590 I 0.853
ENSGALG00000020522 Gallus gallus ENSGALG00000020522 I 0.846
Gfo_R011942 Geospiza fortis Gfo_R011942 I 0.846
ENSFALG00000011806 Ficedula albicollis ENSFALG00000011806 I 0.846
MYRF Meleagris gallopavo ENSMGAG00000004733 I 0.846
ENSTGUG00000006600 Taeniopygia guttata ENSTGUG00000006600 I 0.846
ENSAPLG00000006054 Anas platyrhynchos ENSAPLG00000006054 I 0.846
Aan_R010750 Calypte anna Aan_R010750 I 0.837
ENSMEUG00000004200 Macropus eugenii ENSMEUG00000004200 I 0.835
MYRF Oryctolagus cuniculus ENSOCUG00000003269 I 0.832
MYRF Pteropus vampyrus ENSPVAG00000012342 I 0.825
MYRF Gorilla gorilla ENSGGOG00000012529 I 0.825
MYRF Pan troglodytes ENSPTRG00000003749 I 0.825
MYRF Dasypus novemcinctus ENSDNOG00000005294 I 0.825
ENSPPYG00000003180 Pongo abelii ENSPPYG00000003180 I 0.825
MYRF Sus scrofa ENSSSCG00000013078 I 0.825
MYRF Callithrix jacchus ENSCJAG00000019218 I 0.825
Pvit_15884 Pogona vitticeps Pvit_15884 I 0.825
ENSAMEG00000016669 Ailuropoda melanoleuca ENSAMEG00000016669 I 0.825
Brh_R007745 Buceros rhinoceros Brh_R007745 I 0.825
MYRF Canis familiaris ENSCAFG00000016062 I 0.825
Myrf Dipodomys ordii ENSDORG00000002029 I 0.825
Myrf Rattus norvegicus ENSRNOG00000028274 I 0.825
MYRF Otolemur garnettii ENSOGAG00000010786 I 0.825
Myrf Mus musculus ENSMUSG00000036098 D 0.825
MYRF Felis catus ENSFCAG00000013683 I 0.825
MYRF Homo sapiens ENSG00000124920 D 0.825
Tal_R006175 Tyto alba Tal_R006175 I 0.823
Afo_R010549 Aptenodytes forsteri Afo_R010549 I 0.823
myrf Xenopus tropicalis XB-GENE-1020968 I 0.818
MYRF Macaca mulatta ENSMMUG00000006655 I 0.818
MYRF Bos taurus ENSBTAG00000006990 I 0.818
ENSCSAG00000006452 Chlorocebus sabaeus ENSCSAG00000006452 I 0.818
Alligator_sinensis_CCG012901.1 Alligator sinensis Alligator_sinensis_CCG012901.1 I 0.818
ENSMPUG00000014126 Mustela putorius furo ENSMPUG00000014126 I 0.818
ENSSTOG00000000529 Ictidomys tridecemlineatus ENSSTOG00000000529 I 0.818
ENSPANG00000013413 Papio anubis ENSPANG00000013413 I 0.818
Myotis_brandtii_MRF_10005301 Myotis brandtii Myotis_brandtii_MRF_10005301 I 0.816
MYRF Cavia porcellus ENSCPOG00000013543 I 0.811
ENSSHAG00000002443 Sarcophilus harrisii ENSSHAG00000002443 I 0.811
MYRF Ornithorhynchus anatinus ENSOANG00000003410 I 0.802
ENSBTAP00000009187-D1 Bos grunniens ENSBTAP00000009187-D1 I 0.797
myrf.L Xenopus laevis XB-GENE-1020972 I 0.790
MYRF Equus caballus ENSECAG00000021799 I 0.790
ENSP00000278836 Macaca fascicularis ENSP00000278836 I 0.783
MYRF Procavia capensis ENSPCAG00000017079 I 0.782
MYRF Anolis carolinensis ENSACAG00000017691 I 0.769
ENSOARG00000013482 Ovis aries ENSOARG00000013482 I 0.769
MYRF Myotis lucifugus ENSMLUG00000010326 I 0.762
ENSMMUG00000006501 Macaca mulatta ENSMMUG00000006501 I 0.759
SPU_000601 Strongylocentrotus purpuratus SPU_000601 I 0.725
ENSNLEG00000003069 Nomascus leucogenys ENSNLEG00000003069 I 0.706
Cmyd_10008461 Chelonia mydas Cmyd_10008461 I 0.706