ENSP00000278836 (Macaca fascicularis)
Ndt80/PhoG

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF05224 (NDT80_PhoG) IPR007888 ENSP00000278836 T300186_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a transcription factor that is required for central nervous system myelination and may regulate oligodendrocyte differentiation. It is thought to act by increasing the expression of genes that effect myelin production but may also directly promote myelin gene expression. Loss of a similar gene in mouse models results in severe demyelination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
MYRF
M02385_2.00 		Homo sapiens
TGGTACCA
TGGTACCA		 PBM
Weirauch et al.(2014)
pTH9310 		0.965 0.965
Myrf
M02386_2.00 		Mus musculus
NNGTRHSNNN
NNNSDYACNN		 PBM
Weirauch et al.(2014)
pTH8554 		0.965 0.965
myrf
M02384_2.00 		Danio rerio
TGGTACCR
YGGTACCA		 PBM
Weirauch et al.(2014)
pTH8654 		0.794 0.794
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000278836 Ndt80/PhoG 345 490

Links

Other Ndt80/PhoG family TFs
Other Macaca fascicularis TFs

Invalid Input OrderBy

62 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action