snap_masked-nMf.1.1.scaf18837-processed-gene-0.2 (Meloidogyne floridensis)
Nuclear receptor

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00105 (zf-C4) IPR001628 snap_masked-nMf.1.1.scaf18837-processed-gene-0.2 T310459_2.00 WormBase:ParaSite (2015-Oct-22)
NCBI Gene Info:
This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to transforming growth factor (TGF)-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The protein acts as a tumor suppressor and inhibits epithelial cell proliferation. It may also have an inhibitory effect on tumors by reducing angiogenesis and increasng blood vessel hyperpermeability. The encoded protein is a crucial component of the bone morphogenetic protein signaling pathway. The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. [provided by RefSeq, Aug 2017]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
nhr-3
M00687_2.00
Caenorhabditis elegans
NNHGDHYANN

NNTRDHCDNN
PBM
Narasimhan et al.(2015)
pTH9163
0.985 0.776
For this family, TFs with SR scores > 0.745 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
snap_masked-nMf.1.1.scaf18837-processed-gene-0.2-mRNA-1 Nuclear receptor 1 67

Links

Other Nuclear receptor family TFs
Other Meloidogyne floridensis TFs

129 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
GPLIN_000669000 Globodera pallida GPLIN_000669000 I 0.993
Minc13525 Meloidogyne incognita Minc13525 I 0.993
Minc01725 Meloidogyne incognita Minc01725 I 0.993
maker-nMf.1.1.scaf07948-snap-gene-0.4 Meloidogyne floridensis maker-nMf.1.1.scaf07948-snap-gene-0.4 I 0.993
MhA1_Contig217.frz3.gene7 Meloidogyne hapla MhA1_Contig217.frz3.gene7 I 0.993
BXY_0011200 Bursaphelenchus xylophilus BXY_0011200 I 0.988
WUBG_08518 Wuchereria bancrofti WUBG_08518 I 0.985
Bm14724 Brugia malayi Bm14724 I 0.985
NECAME_04545 Necator americanus NECAME_04545 I 0.985
WBGene00241910 Onchocerca volvulus WBGene00241910 I 0.985
nDi.2.2.2.g05078 Dirofilaria immitis nDi.2.2.2.g05078 I 0.985
CBG07552 Caenorhabditis briggsae CBG07552 I 0.985
nhr-3 Caenorhabditis elegans WBGene00003602 D 0.985
nLs.2.1.2.g05858 Litomosoides sigmodontis nLs.2.1.2.g05858 I 0.985
SMUV_0000428701 Syphacia muris SMUV_0000428701 I 0.985
L596_g25666 Steinernema carpocapsae L596_g25666 I 0.985
BTMF_0000273701 Brugia timori BTMF_0000273701 I 0.985
ASU_10946 Ascaris suum ASU_10946 I 0.985
ANCCAN_18459 Ancylostoma caninum ANCCAN_18459 I 0.985
TCLT_0000079701 Thelazia callipaeda TCLT_0000079701 I 0.985
HCOI02077900 Haemonchus contortus HCOI02077900 I 0.985
nAv.1.0.1.g09896 Acanthocheilonema viteae nAv.1.0.1.g09896 I 0.985
OESDEN_02943 Oesophagostomum dentatum OESDEN_02943 I 0.985
L893_g29555 Steinernema glaseri L893_g29555 I 0.985
TCNE_0001780601 Toxocara canis TCNE_0001780601 I 0.985
nOo.2.0.1.g05901 Onchocerca ochengi nOo.2.0.1.g05901 I 0.985
CRE15289 Caenorhabditis remanei CRE15289 I 0.985
PPA20304 Pristionchus pacificus PPA20304 I 0.985
LOAG_18352 Loa loa LOAG_18352 I 0.985
TELCIR_01879 Teladorsagia circumcincta TELCIR_01879 I 0.985
OFLC_0000776201 Onchocerca flexuosa OFLC_0000776201 I 0.985
L892_g650 Steinernema scapterisci L892_g650 I 0.985
CBN19233 Caenorhabditis brenneri CBN19233 I 0.984
CJA13646 Caenorhabditis japonica CJA13646 I 0.984
ASIM_0001589901 Anisakis simplex ASIM_0001589901 I 0.981
DICVIV_11945 Dictyocaulus viviparus DICVIV_11945 I 0.979
ACOC_0000732601 Angiostrongylus costaricensis ACOC_0000732601 I 0.947
PTRK_0000510500 Parastrongyloides trichosuri PTRK_0000510500 I 0.890
SPAL_0001436300 Strongyloides papillosus SPAL_0001436300 I 0.890
SVE_0301400 Strongyloides venezuelensis SVE_0301400 I 0.890
SSTP_0000831700 Strongyloides stercoralis SSTP_0000831700 I 0.890
SVUK_0001012101 Strongylus vulgaris SVUK_0001012101 I 0.885
BXY_1600300 Bursaphelenchus xylophilus BXY_1600300 I 0.877
GPLIN_000268400 Globodera pallida GPLIN_000268400 I 0.877
MhA1_Contig984.frz3.gene20 Meloidogyne hapla MhA1_Contig984.frz3.gene20 I 0.877
SSTP_0000217700 Strongyloides stercoralis SSTP_0000217700 I 0.864
SVE_1633700 Strongyloides venezuelensis SVE_1633700 I 0.864
PTRK_0000775900 Parastrongyloides trichosuri PTRK_0000775900 I 0.864
SPAL_0001157400 Strongyloides papillosus SPAL_0001157400 I 0.864
L596_g27086 Steinernema carpocapsae L596_g27086 I 0.862
L898_g4801 Steinernema monticolum L898_g4801 I 0.860
L893_g6878 Steinernema glaseri L893_g6878 I 0.860
L889_g29204 Steinernema feltiae L889_g29204 I 0.860
DME_0000480501 Dracunculus medinensis DME_0000480501 I 0.850
nOo.2.0.1.g04046 Onchocerca ochengi nOo.2.0.1.g04046 I 0.849
NECAME_05125 Necator americanus NECAME_05125 I 0.849
nAv.1.0.1.g01698 Acanthocheilonema viteae nAv.1.0.1.g01698 I 0.849
NBR_0000170601 Nippostrongylus brasiliensis NBR_0000170601 I 0.849
nDi.2.2.2.g02781 Dirofilaria immitis nDi.2.2.2.g02781 I 0.849
nLs.2.1.2.g08709 Litomosoides sigmodontis nLs.2.1.2.g08709 I 0.849
BTMF_0001198801 Brugia timori BTMF_0001198801 I 0.849
CJA04720 Caenorhabditis japonica CJA04720 I 0.849
TCLT_0000173501 Thelazia callipaeda TCLT_0000173501 I 0.849
LOAG_05485 Loa loa LOAG_05485 I 0.849
CBG19604 Caenorhabditis briggsae CBG19604 I 0.849
Bm4894 Brugia malayi Bm4894 I 0.849
WUBG_10752 Wuchereria bancrofti WUBG_10752 I 0.849
Bm12053 Brugia malayi Bm12053 I 0.849
OESDEN_17109 Oesophagostomum dentatum OESDEN_17109 I 0.849
WBGene00248075 Onchocerca volvulus WBGene00248075 I 0.849
HCOI01268300 Haemonchus contortus HCOI01268300 I 0.849
OFLC_0001511801 Onchocerca flexuosa OFLC_0001511801 I 0.849
Hba_14163 Heterorhabditis bacteriophora Hba_14163 I 0.849
ANCCAN_12539 Ancylostoma caninum ANCCAN_12539 I 0.849
GPUH_0000393501 Gongylonema pulchrum GPUH_0000393501 I 0.849
CBN07936 Caenorhabditis brenneri CBN07936 I 0.846
CBN20828 Caenorhabditis brenneri CBN20828 I 0.846
CRE06667 Caenorhabditis remanei CRE06667 I 0.846
nhr-88 Caenorhabditis elegans WBGene00003678 I 0.846
ACAC_0001180201 Angiostrongylus cantonensis ACAC_0001180201 I 0.845
snap_masked-nMf.1.1.scaf24311-processed-gene-0.3 Meloidogyne floridensis snap_masked-nMf.1.1.scaf24311-processed-gene-0.3 I 0.844
Minc15420 Meloidogyne incognita Minc15420 I 0.844
DME_0000960901 Dracunculus medinensis DME_0000960901 I 0.843
L596_g25297 Steinernema carpocapsae L596_g25297 I 0.835
L889_g8361 Steinernema feltiae L889_g8361 I 0.835
L898_g10316 Steinernema monticolum L898_g10316 I 0.835
scaffold51-EXSNAP2012.23 Pristionchus exspectatus scaffold51-EXSNAP2012.23 I 0.830
PPA21285 Pristionchus pacificus PPA21285 I 0.830
L892_g19201 Steinernema scapterisci L892_g19201 I 0.824
ASIM_0001309901 Anisakis simplex ASIM_0001309901 I 0.818
DME_0000742401 Dracunculus medinensis DME_0000742401 I 0.808
HPLM_0001680701 Haemonchus placei HPLM_0001680701 I 0.808
ANCCEY_03357 Ancylostoma ceylanicum ANCCEY_03357 I 0.808
OESDEN_02652 Oesophagostomum dentatum OESDEN_02652 I 0.808
DICVIV_02348 Dictyocaulus viviparus DICVIV_02348 I 0.808
L596_g27130 Steinernema carpocapsae L596_g27130 I 0.808
HPBE_0001043101 Heligmosomoides bakeri HPBE_0001043101 I 0.808
HCOI00769300 Haemonchus contortus HCOI00769300 I 0.808
HCOI01406200 Haemonchus contortus HCOI01406200 I 0.808
ACAC_0000239001 Angiostrongylus cantonensis ACAC_0000239001 I 0.808
CBG19594 Caenorhabditis briggsae CBG19594 I 0.808
TELCIR_05080 Teladorsagia circumcincta TELCIR_05080 I 0.808
TELCIR_07363 Teladorsagia circumcincta TELCIR_07363 I 0.808
CBN31048 Caenorhabditis brenneri CBN31048 I 0.808
CRE06661 Caenorhabditis remanei CRE06661 I 0.808
NECAME_12696 Necator americanus NECAME_12696 I 0.808
nhr-119 Caenorhabditis elegans WBGene00003709 I 0.808
NBR_0001432001 Nippostrongylus brasiliensis NBR_0001432001 I 0.808
ACOC_0001326501 Angiostrongylus costaricensis ACOC_0001326501 I 0.808
Hba_14958 Heterorhabditis bacteriophora Hba_14958 I 0.801
L889_g29246 Steinernema feltiae L889_g29246 I 0.796
L889_g5777 Steinernema feltiae L889_g5777 I 0.795
L898_g14928 Steinernema monticolum L898_g14928 I 0.784
BXY_1595900 Bursaphelenchus xylophilus BXY_1595900 I 0.784
EVEC_0000733201 Enterobius vermicularis EVEC_0000733201 N 0.782
L893_g29388 Steinernema glaseri L893_g29388 I 0.775
L596_g20569 Steinernema carpocapsae L596_g20569 I 0.775
L898_g24498 Steinernema monticolum L898_g24498 I 0.775
genemark-nMf.1.1.scaf00140-processed-gene-0.6 Meloidogyne floridensis genemark-nMf.1.1.scaf00140-processed-gene-0.6 I 0.775
SVE_0137800 Strongyloides venezuelensis SVE_0137800 I 0.770
SPAL_0000110800 Strongyloides papillosus SPAL_0000110800 I 0.770
SSTP_0001234400 Strongyloides stercoralis SSTP_0001234400 I 0.770
L596_g3812 Steinernema carpocapsae L596_g3812 I 0.759
L893_g27196 Steinernema glaseri L893_g27196 I 0.759
L889_g6303 Steinernema feltiae L889_g6303 I 0.759
L898_g23965 Steinernema monticolum L898_g23965 I 0.759
Ppa-nhr-3 Pristionchus pacificus PPA28597 I 0.753
scaffold395-EXSNAP2012.23 Pristionchus exspectatus scaffold395-EXSNAP2012.23 I 0.753
L892_g21738 Steinernema scapterisci L892_g21738 I 0.746