mbr-1 (Caenorhabditis elegans)
Pipsqueak

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF05225 (HTH_psq) IPR007889 WBGene00011315 T314398_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including AUA; intestine; nerve ring neurons; tail; and vulva. Orthologous to human LCOR (ligand dependent nuclear receptor corepressor) and LCORL (ligand dependent nuclear receptor corepressor like). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
mbr-1
M00707_2.00		 Caenorhabditis elegans
NRNGGGCCDN
NHGGCCCNYN		 PBM
Narasimhan et al.(2015)
pTH10031		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.778 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00707_2.00 Pipsqueak 51 93

DNA Binding Domains

Protein ID Domain From To Sequence
T01C1.2 Pipsqueak 155 197

Links

Other Pipsqueak family TFs
Other Caenorhabditis elegans TFs

9 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
NECAME_06709 Necator americanus NECAME_06709 I 0.850
OESDEN_00123 Oesophagostomum dentatum OESDEN_00123 I 0.850
CGOC_0000231801 Cylicostephanus goldi CGOC_0000231801 I 0.850
DICVIV_13091 Dictyocaulus viviparus DICVIV_13091 I 0.829
ANCDUO_12249 Ancylostoma duodenale ANCDUO_12249 I 0.829
ANCDUO_25789 Ancylostoma duodenale ANCDUO_25789 I 0.829
TELCIR_00496 Teladorsagia circumcincta TELCIR_00496 I 0.810
nRc.2.0.1.g13586 Romanomermis culicivorax nRc.2.0.1.g13586 N 0.810
Ppa-mbr-1 Pristionchus pacificus PPA15862 I 0.810