TBR1 (Homo sapiens)
T-box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00907 (T-box) IPR001699 ENSG00000136535 T339893_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
TBR1
M03560_2.00
Homo sapiens
AGGTGTGAAN

NTTCACACCT
SELEX
Jolma et al.(2013)
TBR1_1
(Direct) (Direct)
TBR1
M03561_2.00
Homo sapiens
RAGGTGTGAAH

DTTCACACCTY
SELEX
Jolma et al.(2013)
TBR1_2
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Tbr1
M01028_2.00
Mus musculus
DTVRCAMNYH

DRNKTGYBAH
PBM
SebePedros et al.(2013)
pTH2659
0.530 1.000
Eomes
M00215_2.00
Mus musculus
RDGTGYBANN

NNTVRCACHY
PBM
Badis et al.(2009)
Eomes_0921
0.865 0.874
EOMES
M03563_2.00
Homo sapiens
DAGGTGTGAWNNN

NNNWTCACACCTH
SELEX
Jolma et al.(2013)
EOMES_1
0.865 0.869
EOMES
M03564_2.00
Homo sapiens
TVACACNTNNNDRNGTGTGA

TCACACNYHNNNANGTGTBA
SELEX
Jolma et al.(2013)
EOMES_2
0.865 0.869
EOMES
M02752_2.00
Homo sapiens
AGGTGTGAW

WTCACACCT
SELEX
Jolma et al.(2010)
EOMES_monomer
0.865 0.869
EOMES
M05807_2.00
Homo sapiens
DAGGTGTGAN

NTCACACCTH
SELEX
Yin et al.(2017)
EOMES_eDBD_HT-SELEX
0.865 0.869
EOMES
M09647_2.00
Homo sapiens
ARGTGWKAAN

NTTMWCACYT
Misc
Heinz et al.(2010)
H9-Eomes_GSE26097
0.865 0.869
EOMES
M05808_2.00
Homo sapiens
NABGTGYKAH

DTMRCACVTN
SELEX
Yin et al.(2017)
EOMES_eDBD_Methyl-HT-SELEX
0.865 0.869
A0A075Q982_PATMI
M00734_2.00
Patiria miniata
NAGGTGTBAN

NTVACACCTN
PBM
Cheatle-Jarvela et al.(2014)
PmTbr
0.789 0.645
TBX21
M03546_2.00
Homo sapiens
GGTGTGAHDTMACACY

RGTGTKAHDTCACACC
SELEX
Jolma et al.(2013)
TBX21_1
0.766 0.732
TBX21
M03547_2.00
Homo sapiens
DAGGTGTGAW

WTCACACCTH
SELEX
Jolma et al.(2013)
TBX21_2
0.766 0.732
TBX21
M03548_2.00
Homo sapiens
TMACACYTNNDAGGTGTGA

TCACACCTHNNARGTGTKA
SELEX
Jolma et al.(2013)
TBX21_3
0.766 0.732
TBX21
M03549_2.00
Homo sapiens
GGTGTGAWATCACACC

GGTGTGATWTCACACC
SELEX
Jolma et al.(2013)
TBX21_4
0.766 0.732
TBX21
M03550_2.00
Homo sapiens
DAGGTGTGAW

WTCACACCTH
SELEX
Jolma et al.(2013)
TBX21_5
0.766 0.732
TBX21
M03551_2.00
Homo sapiens
TSACACCWNMRAGGTGTGA

TCACACCTYKNWGGTGTSA
SELEX
Jolma et al.(2013)
TBX21_6
0.766 0.732
TBX21
M05793_2.00
Homo sapiens
DAGGTGTKAN

NTMACACCTH
SELEX
Yin et al.(2017)
TBX21_eDBD_HT-SELEX
0.766 0.732
TBX21
M09425_2.00
Homo sapiens
NDSDRGSTGWBRN

NYVWCASCYHSHN
Misc
Kulakovskiy et al.(2013)
TBX21_HUMAN.H11MO.0.A
0.766 0.732
Tbx21
M09428_2.00
Mus musculus
DNDDSTGWSDND

HNHSWCASHHNH
Misc
Kulakovskiy et al.(2013)
TBX21_MOUSE.H11MO.0.A
0.766 0.732
Tbx21
M09648_2.00
Mus musculus
ADGTGWSAHN

NDTSWCACHT
Misc
Heinz et al.(2010)
CD8-Tbet_GSE33802
0.766 0.732
TBX21
M05794_2.00
Homo sapiens
DASGTGTKAW

WTMACACSTH
SELEX
Yin et al.(2017)
TBX21_eDBD_Methyl-HT-SELEX
0.766 0.732
SPU_025584
M00733_2.00
Strongylocentrotus purpuratus
RGGTGTGANN

NNTCACACCY
PBM
Cheatle-Jarvela et al.(2014)
SpTbr
0.762 0.617
For this family, TFs with SR scores > 0.734 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000374205 T-box 206 393
ENSP00000387023 T-box 1 106
ENSP00000393934 T-box 1 128

Links

Other T-box family TFs
Other Homo sapiens TFs

219 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
AGABI2DRAFT_239429 Agaricus bisporus AGABI2DRAFT_239429 N 0.000
BN946_scf184920.g52 Trametes cinnabarina BN946_scf184920.g52 I 0.000
BOTBODRAFT_93074 Botryobasidium botryosum BOTBODRAFT_93074 N 0.000
CC1G_08635 Coprinopsis cinerea CC1G_08635 N 0.000
CERSUDRAFT_109986 Ceriporiopsis subvermispora CERSUDRAFT_109986 N 0.000
CY34DRAFT_809202 Suillus luteus CY34DRAFT_809202 N 0.000
DACRYDRAFT_24120 Dacryopinax sp DACRYDRAFT_24120 I 0.000
DICSQDRAFT_66188 Dichomitus squalens DICSQDRAFT_66188 I 0.000
fgenesh1_pg.C_scaffold_14000237 Phanerochaete chrysosporium fgenesh1_pg.C_scaffold_14000237 N 0.000
FIBRA_01656 Fibroporia radiculosa FIBRA_01656 I 0.000
FOMPIDRAFT_1017957 Fomitopsis pinicola FOMPIDRAFT_1017957 N 0.000
GALMADRAFT_217801 Galerina marginata GALMADRAFT_217801 N 0.000
GLOTRDRAFT_69493 Gloeophyllum trabeum GLOTRDRAFT_69493 I 0.000
gw1.1.2337.1 Heterobasidion annosum gw1.1.2337.1 N 0.000
HETIRDRAFT_443323 Heterobasidion irregulare HETIRDRAFT_443323 N 0.000
HYDPIDRAFT_161884 Hydnomerulius pinastri HYDPIDRAFT_161884 N 0.000
JAAARDRAFT_60403 Jaapia argillacea JAAARDRAFT_60403 N 0.000
K443DRAFT_677716 Laccaria amethystina K443DRAFT_677716 N 0.000
LACBIDRAFT_242593 Laccaria bicolor LACBIDRAFT_242593 N 0.000
M378DRAFT_66555 Amanita muscaria M378DRAFT_66555 N 0.000
M404DRAFT_43642 Pisolithus tinctorius M404DRAFT_43642 N 0.000
M407DRAFT_78353 Tulasnella calospora M407DRAFT_78353 N 0.000
M408DRAFT_34303 Serendipita vermifera M408DRAFT_34303 N 0.000
M413DRAFT_232462 Hebeloma cylindrosporum M413DRAFT_232462 N 0.000
M422DRAFT_84080 Sphaerobolus stellatus M422DRAFT_84080 N 0.000
Moror_376 Moniliophthora roreri Moror_376 I 0.000
MPER_01714 Moniliophthora perniciosa MPER_01714 I 0.000
PAXRUDRAFT_30646 Paxillus rubicundulus PAXRUDRAFT_30646 N 0.000
PHLGIDRAFT_129508 Phlebiopsis gigantea PHLGIDRAFT_129508 N 0.000
PIIN_04121 Piriformospora indica PIIN_04121 N 0.000
PILCRDRAFT_818339 Piloderma croceum PILCRDRAFT_818339 N 0.000
PISMIDRAFT_69441 Pisolithus microcarpus PISMIDRAFT_69441 N 0.000
PISMIDRAFT_70573 Pisolithus microcarpus PISMIDRAFT_70573 N 0.000
PLEOSDRAFT_1111247 Pleurotus ostreatus PLEOSDRAFT_1111247 N 0.000
POSPLDRAFT_93814 Postia placenta POSPLDRAFT_93814 I 0.000
SCHCODRAFT_79748 Schizophyllum commune SCHCODRAFT_79748 N 0.000
SCLCIDRAFT_18203 Scleroderma citrinum SCLCIDRAFT_18203 N 0.000
SERLA73DRAFT_78019 Serpula lacrymans SERLA73DRAFT_78019 N 0.000
V565_015180 Rhizoctonia solani V565_015180 N 0.000