ISL1 (Choloepus hoffmanni)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSCHOG00000012504 T207802_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Isl2
M00458_2.00 		Mus musculus
NWDWDNN
NNHWHWN		 PBM
Berger et al.(2008)
Isl2_3430 		0.867 1.000
ISL2
M03177_2.00 		Homo sapiens
YTAAKTGB
VCAMTTAR		 SELEX
Jolma et al.(2013)
ISL2_1 		0.867 1.000
ISL1
M04908_2.00 		Homo sapiens
BTAAKTGS
SCAMTTAV		 SELEX
Yin et al.(2017)
ISL1_eDBD_HT-SELEX 		0.867 1.000
ISL1
M04910_2.00 		Homo sapiens
NTAAKTGS
SCAMTTAN		 SELEX
Yin et al.(2017)
ISL1_FL_HT-SELEX 		0.867 1.000
ISL2
M05204_2.00 		Homo sapiens
NTAAKTGS
SCAMTTAN		 SELEX
Yin et al.(2017)
ISL2_eDBD_HT-SELEX 		0.867 1.000
ISL1
M09128_2.00 		Homo sapiens
NYWRAKKGV
BCMMTYWRN		 Misc
Kulakovskiy et al.(2013)
ISL1_HUMAN.H11MO.0.A 		0.867 1.000
Isl1
M09209_2.00 		Mus musculus
NYWRAKKGV
BCMMTYWRN		 Misc
Kulakovskiy et al.(2013)
ISL1_MOUSE.H11MO.0.A 		0.867 1.000
Isl1
M09578_2.00 		Mus musculus
YTAAKKGV
BCMMTTAR		 Misc
Heinz et al.(2010)
Neuron-Isl1_GSE31456 		0.867 1.000
ISL1
M10634_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ISL1_Q3 		0.867 1.000
ISL1
M10635_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ISL1_Q6 		0.867 1.000
ISL1
M04909_2.00 		Homo sapiens
BTAAKTGS
SCAMTTAV		 SELEX
Yin et al.(2017)
ISL1_eDBD_Methyl-HT-SELEX 		0.867 1.000
ISL1
M04911_2.00 		Homo sapiens
BTAAKTGS
SCAMTTAV		 SELEX
Yin et al.(2017)
ISL1_FL_Methyl-HT-SELEX 		0.867 1.000
ISL2
M05205_2.00 		Homo sapiens
NTAAKTGN
NCAMTTAN		 SELEX
Yin et al.(2017)
ISL2_eDBD_Methyl-HT-SELEX 		0.867 1.000
ISL2B_ONCTS
M10798_2.00 		Oncorhynchus tshawytscha Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ISL2_02 		0.866 0.982
ISL2B_ONCTS
M10799_2.00 		Oncorhynchus tshawytscha Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ISL2_03 		0.866 0.982
ISL2B_ONCTS
M10800_2.00 		Oncorhynchus tshawytscha Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ISL2_04 		0.866 0.982
ISL2B_ONCTS
M10801_2.00 		Oncorhynchus tshawytscha Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ISL2_05 		0.866 0.982
tup
M06498_2.00 		Drosophila melanogaster
WTAATKG
CMATTAW		 B1H
Mathelier et al.(2014)
MA0248.1 		0.864 0.965
tup
M06270_2.00 		Drosophila melanogaster
SWTAATKG
CMATTAWS		 B1H
Zhu et al.(2011)
Tup_Cell_FBgn0003896 		0.864 0.965
tup
M06271_2.00 		Drosophila melanogaster
NYTAATKRV
BYMATTARN		 B1H
Zhu et al.(2011)
tup_SOLEXA_10_FBgn0003896 		0.864 0.965
tup
M06272_2.00 		Drosophila melanogaster
YTAATKR
YMATTAR		 B1H
Zhu et al.(2011)
Tup_SOLEXA_FBgn0003896 		0.864 0.965
CBG04010
M01242_2.00 		Caenorhabditis briggsae
NNKTAATDDMN
NKHHATTAMNN		 PBM
Lambert et al.(2019)
pTH11489 		0.835 0.772
NEMVEDRAFT_v1g81309
M02152_2.00 		Nematostella vectensis
NTAATDNNN
NNNHATTAN		 PBM
Weirauch et al.(2014)
pTH5477 		0.636 0.351
NOTO
M03241_2.00 		Homo sapiens
NNTAATKWRN
NYWMATTANN		 SELEX
Jolma et al.(2013)
NOTO_1 		0.631 0.368
NOTO
M05390_2.00 		Homo sapiens
BTAATKRV
BYMATTAV		 SELEX
Yin et al.(2017)
NOTO_eDBD_HT-SELEX 		0.631 0.368
NOTO
M05391_2.00 		Homo sapiens
BTMATKRV
BYMATKAV		 SELEX
Yin et al.(2017)
NOTO_eDBD_Methyl-HT-SELEX 		0.631 0.368
PHOX2B
M00278_2.00 		Homo sapiens
NNNNNRY
RYNNNNN		 PBM
Barrera et al.(2016)
PHOX2B_Q143R 		0.623 0.368
Noto
M02101_2.00 		Mus musculus
NNHHATDDNN
NNHHATDDNN		 PBM
Weirauch et al.(2014)
pTH6268 		0.613 0.351
VSX1
M00269_2.00 		Homo sapiens
NNWAAYNNN
NNNRTTWNN		 PBM
Barrera et al.(2016)
VSX1_REF 		0.608 0.386
Vsx1
M00459_2.00 		Mus musculus
NNTAATDDN
NHHATTANN		 PBM
Berger et al.(2008)
Vsx1_1728 		0.608 0.386
Vsx1
M03267_2.00 		Mus musculus
NTAATTRN
NYAATTAN		 SELEX
Jolma et al.(2013)
Vsx1_1 		0.608 0.386
VSX1
M00266_2.00 		Homo sapiens
NNTAAYNNN
NNNRTTANN		 PBM
Barrera et al.(2016)
VSX1_G160D 		0.608 0.386
Sebox
M02097_2.00 		Mus musculus
NHTTAATTAN
NTAATTAADN		 PBM
Weirauch et al.(2014)
pTH6379 		0.605 0.421
ceh-5
M02179_2.00 		Caenorhabditis elegans
NNTAATDDN
NHHATTANN		 PBM
Weirauch et al.(2014)
pTH6562 		0.604 0.368
SHOX
M02095_2.00 		Homo sapiens
NTAATTRN
NYAATTAN		 PBM
Weirauch et al.(2014)
pTH5805 		0.601 0.404
Shox2
M00439_2.00 		Mus musculus
NTAATDDN
NHHATTAN		 PBM
Berger et al.(2008)
Shox2_2641 		0.601 0.404
SHOX
M03232_2.00 		Homo sapiens
NTAATTRN
NYAATTAN		 SELEX
Jolma et al.(2013)
SHOX_1 		0.601 0.404
SHOX2
M03204_2.00 		Homo sapiens
BTAATTRN
NYAATTAV		 SELEX
Jolma et al.(2013)
SHOX2_1 		0.601 0.404
Shox2
M03263_2.00 		Mus musculus
NTAATTRN
NYAATTAN		 SELEX
Jolma et al.(2013)
Shox2_1 		0.601 0.404
CG5369
M03876_2.00 		Drosophila melanogaster
TAATTHVATTA
TAATBDAATTA		 SELEX
Nitta et al.(2015)
CG5369_1 		0.601 0.404
CG5369
M03877_2.00 		Drosophila melanogaster
TAATTRNNTAATBN
NVATTANNYAATTA		 SELEX
Nitta et al.(2015)
CG5369_2 		0.601 0.404
CG5369
M03878_2.00 		Drosophila melanogaster
TAATTVRATWA
TWATYBAATTA		 SELEX
Nitta et al.(2015)
CG5369_3 		0.601 0.404
SHOX
M05366_2.00 		Homo sapiens
NTAATTRV
BYAATTAN		 SELEX
Yin et al.(2017)
SHOX_eDBD_HT-SELEX 		0.601 0.404
Shox2
M10772_2.00 		Rattus norvegicus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SHOX2_05 		0.601 0.404
SHOX
M05367_2.00 		Homo sapiens
NTAATTRV
BYAATTAN		 SELEX
Yin et al.(2017)
SHOX_eDBD_Methyl-HT-SELEX_1 		0.601 0.404
SHOX
M05368_2.00 		Homo sapiens
NTAAYGAN
NTCRTTAN		 SELEX
Yin et al.(2017)
SHOX_eDBD_Methyl-HT-SELEX_2 		0.601 0.404
C4B866_NEMVE
M02052_2.00 		Nematostella vectensis
NNTTAATTARNN
NNYTAATTAANN		 PBM
Weirauch et al.(2014)
pTH6176 		0.600 0.421
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSCHOP00000011070 Homeodomain 182 238

Links

Other Homeodomain family TFs
Other Choloepus hoffmanni TFs

604 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
DREB1A Oryza sativa OS09G0522200 D 0.000
Q8GZQ2_MAIZE Zea mays Q8GZQ2_MAIZE D 0.000
Traes_5BL_D16B19610 Triticum aestivum Traes_5BL_D16B19610 I 0.000
Sb02g030320 Sorghum bicolor Sb02g030320 I 0.000
Sb02g030330 Sorghum bicolor Sb02g030330 I 0.000
Sb02g030340 Sorghum bicolor Sb02g030340 I 0.000
Sb05g006275 Sorghum bicolor Sb05g006275 I 0.000
Si030998m.g Setaria italica Si030998m.g I 0.000
Si031001m.g Setaria italica Si031001m.g I 0.000
ORGLA08G0220100 Oryza glaberrima ORGLA08G0220100 I 0.000
Pavir.Ba01280 Panicum virgatum Pavir.Ba01280 I 0.000
Pavir.Ba01281 Panicum virgatum Pavir.Ba01281 I 0.000
Pavir.Fb02246 Panicum virgatum Pavir.Fb02246 I 0.000
Pavir.J03891 Panicum virgatum Pavir.J03891 I 0.000
Pavir.J03892 Panicum virgatum Pavir.J03892 I 0.000
Pavir.J03893 Panicum virgatum Pavir.J03893 I 0.000
Pavir.J27101 Panicum virgatum Pavir.J27101 I 0.000
LPERR09G12950 Leersia perrieri LPERR09G12950 I 0.000
BRADI4G35610 Brachypodium distachyon BRADI4G35610 I 0.000
BRADI4G35650 Brachypodium distachyon BRADI4G35650 I 0.000
F775_27111 Aegilops tauschii F775_27111 I 0.000
GRMZM2G069082 Zea mays GRMZM2G069082 I 0.000
GRMZM2G069126 Zea mays GRMZM2G069126 I 0.000
GRMZM2G069146 Zea mays GRMZM2G069146 I 0.000
GRMZM2G124011 Zea mays GRMZM2G124011 I 0.000
GRMZM2G124037 Zea mays GRMZM2G124037 I 0.000
DREB1A Oryza indica BGIOSGA029415 I 0.000
OBART09G16810 Oryza barthii OBART09G16810 I 0.000
OBART09G16830 Oryza barthii OBART09G16830 I 0.000
OGLUM09G17430 Oryza glumaepatula OGLUM09G17430 I 0.000
OMERI09G12490 Oryza meridionalis OMERI09G12490 I 0.000
ONIVA09G17900 Oryza nivara ONIVA09G17900 I 0.000
OPUNC09G15260 Oryza punctata OPUNC09G15260 I 0.000
OPUNC09G15290 Oryza punctata OPUNC09G15290 I 0.000