IRF6 (Homo sapiens)
IRF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00605 (IRF) IPR001346 ENSG00000117595 T244077_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
IRF6
M05527_2.00		 Homo sapiens
RGTWTCGNNNNNNYGAWACY
RGTWTCRNNNNNNCGAWACY		 SELEX
Yin et al.(2017)
IRF6_eDBD_HT-SELEX		 (Direct) (Direct)
IRF6
M05528_2.00		 Homo sapiens
RGTWTCGNHNNDNYGAWACY
RGTWTCRNHNNDNCGAWACY		 SELEX
Yin et al.(2017)
IRF6_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
IRF6
M05529_2.00		 Homo sapiens
ACCGAAACT
AGTTTCGGT		 SELEX
Yin et al.(2017)
IRF6_FL_HT-SELEX		 (Direct) (Direct)
IRF6
M05530_2.00		 Homo sapiens
ACCGAWACY
RGTWTCGGT		 SELEX
Yin et al.(2017)
IRF6_FL_Methyl-HT-SELEX		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Irf6
M00176_2.00 		Mus musculus
NNNHGADASN
NSTHTCDNNN		 PBM
Badis et al.(2009)
Irf6_3803 		1.000 1.000
IRF6
M02254_2.00 		Meleagris gallopavo
NRNCGAWACY
RGTWTCGNYN		 PBM
Weirauch et al.(2014)
pTH9210 		0.943 0.943
IRF6
M02253_2.00 		Gallus gallus
NNMCNAAWNN
NNWTTNGKNN		 PBM
Weirauch et al.(2014)
pTH9178 		0.933 0.933
irf6.2
M02259_2.00 		Xenopus tropicalis
NVNHGAWACH
DGTWTCDNBN		 PBM
Weirauch et al.(2014)
pTH9302 		0.914 0.914
irf5.L
M02260_2.00 		Xenopus laevis
VNCGADACHN
NDGTHTCGNB		 PBM
Weirauch et al.(2014)
pTH9367 		0.790 0.790
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000355988 IRF 9 114
ENSP00000403855 IRF 9 114

Links

Other IRF family TFs
Other Homo sapiens TFs

91 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ACAC_0000945701 Angiostrongylus cantonensis ACAC_0000945701 N
ACOC_0000968101 Angiostrongylus costaricensis ACOC_0000968101 N
ANCCAN_18878 Ancylostoma caninum ANCCAN_18878 I
ANCCEY_14798 Ancylostoma ceylanicum ANCCEY_14798 N
ANCDUO_21609 Ancylostoma duodenale ANCDUO_21609 I
ASIM_0001398401 Anisakis simplex ASIM_0001398401 N
Bm6553 Brugia malayi Bm6553 N
BXY_0367500 Bursaphelenchus xylophilus BXY_0367500 N
CBG05538 Caenorhabditis briggsae CBG05538 I
CBN19762 Caenorhabditis brenneri CBN19762 I
CGOC_0000345301 Cylicostephanus goldi CGOC_0000345301 I
CRE21236 Caenorhabditis remanei CRE21236 I
DICVIV_05295 Dictyocaulus viviparus DICVIV_05295 N
DME_0000033301 Dracunculus medinensis DME_0000033301 N
GPUH_0001120501 Gongylonema pulchrum GPUH_0001120501 N
Hba_18627 Heterorhabditis bacteriophora Hba_18627 I
HCOI02081600 Haemonchus contortus HCOI02081600 N
HPBE_0001384101 Heligmosomoides bakeri HPBE_0001384101 N
HPLM_0000626701 Haemonchus placei HPLM_0000626701 N
L893_g17711 Steinernema glaseri L893_g17711 N
NBR_0001584001 Nippostrongylus brasiliensis NBR_0001584001 N
NBR_0002149901 Nippostrongylus brasiliensis NBR_0002149901 N
nDi.2.2.2.g11238 Dirofilaria immitis nDi.2.2.2.g11238 I
nLs.2.1.2.g08792 Litomosoides sigmodontis nLs.2.1.2.g08792 N
OESDEN_01522 Oesophagostomum dentatum OESDEN_01522 N
PPA12559 Pristionchus pacificus PPA12559 N
TCLT_0000958101 Thelazia callipaeda TCLT_0000958101 N
WBGene00242919 Onchocerca volvulus WBGene00242919 N
WUBG_06876 Wuchereria bancrofti WUBG_06876 N
Y44A6D.3 Caenorhabditis elegans WBGene00012854 D