irf5.L (Xenopus laevis)
IRF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00605 (IRF) IPR001346 XB-GENE-998629 T244635_2.00 Misc (2018-Jan-19)

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
irf5.L
M02260_2.00		 Xenopus laevis
VNCGADACHN
NDGTHTCGNB		 PBM
Weirauch et al.(2014)
pTH9367		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Irf6
M00176_2.00 		Mus musculus
NNNHGADASN
NSTHTCDNNN		 PBM
Badis et al.(2009)
Irf6_3803 		0.790 0.790
IRF6
M05527_2.00 		Homo sapiens
RGTWTCGNNNNNNYGAWACY
RGTWTCRNNNNNNCGAWACY		 SELEX
Yin et al.(2017)
IRF6_eDBD_HT-SELEX 		0.790 0.790
IRF6
M05529_2.00 		Homo sapiens
ACCGAAACT
AGTTTCGGT		 SELEX
Yin et al.(2017)
IRF6_FL_HT-SELEX 		0.790 0.790
IRF6
M05528_2.00 		Homo sapiens
RGTWTCGNHNNDNYGAWACY
RGTWTCRNHNNDNCGAWACY		 SELEX
Yin et al.(2017)
IRF6_eDBD_Methyl-HT-SELEX 		0.790 0.790
IRF6
M05530_2.00 		Homo sapiens
ACCGAWACY
RGTWTCGGT		 SELEX
Yin et al.(2017)
IRF6_FL_Methyl-HT-SELEX 		0.790 0.790
IRF6
M02254_2.00 		Meleagris gallopavo
NRNCGAWACY
RGTWTCGNYN		 PBM
Weirauch et al.(2014)
pTH9210 		0.781 0.781
IRF6
M02253_2.00 		Gallus gallus
NNMCNAAWNN
NNWTTNGKNN		 PBM
Weirauch et al.(2014)
pTH9178 		0.771 0.771
irf6.2
M02259_2.00 		Xenopus tropicalis
NVNHGAWACH
DGTWTCDNBN		 PBM
Weirauch et al.(2014)
pTH9302 		0.752 0.752
Irf5
M00177_2.00 		Mus musculus
NNNHGADASH
DSTHTCDNNN		 PBM
Badis et al.(2009)
Irf5_3874 		0.724 0.724
IRF5
M02256_2.00 		Oryctolagus cuniculus
NHCGAAACYN
NRGTTTCGDN		 PBM
Weirauch et al.(2014)
pTH9272 		0.724 0.724
IRF5
M03332_2.00 		Homo sapiens
YCGAAACCGAAMCY
RGKTTCGGTTTCGR		 SELEX
Jolma et al.(2013)
IRF5_1 		0.724 0.724
IRF5
M03333_2.00 		Homo sapiens
HACCGAAACYV
BRGTTTCGGTD		 SELEX
Jolma et al.(2013)
IRF5_2 		0.724 0.724
IRF5
M05535_2.00 		Homo sapiens
NCGAAACCGAWACH
DGTWTCGGTTTCGN		 SELEX
Yin et al.(2017)
IRF5_eDBD_HT-SELEX 		0.724 0.724
IRF5
M05537_2.00 		Homo sapiens
NCGAAACCGAAACY
RGTTTCGGTTTCGN		 SELEX
Yin et al.(2017)
IRF5_FL_HT-SELEX 		0.724 0.724
IRF5
M10884_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$IRF5_Q3 		0.724 0.724
IRF5
M05536_2.00 		Homo sapiens
NYGAWACYGAWACH
DGTWTCRGTWTCRN		 SELEX
Yin et al.(2017)
IRF5_eDBD_Methyl-HT-SELEX 		0.724 0.724
IRF5
M05538_2.00 		Homo sapiens
NYGAAACCGAWACY
RGTWTCGGTTTCRN		 SELEX
Yin et al.(2017)
IRF5_FL_Methyl-HT-SELEX 		0.724 0.724
For this family, TFs with SR scores > 0.700 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M02260_2.00 IRF 9 114

DNA Binding Domains

Protein ID Domain From To Sequence
AAH82862 IRF 9 114

Links

Other IRF family TFs
Other Xenopus laevis TFs

125 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ACAC_0000945701 Angiostrongylus cantonensis ACAC_0000945701 N
ANCCAN_18878 Ancylostoma caninum ANCCAN_18878 I
ANCDUO_21609 Ancylostoma duodenale ANCDUO_21609 I
ASIM_0001398401 Anisakis simplex ASIM_0001398401 N
BXY_0367500 Bursaphelenchus xylophilus BXY_0367500 N
CBG05538 Caenorhabditis briggsae CBG05538 I
CGOC_0000345301 Cylicostephanus goldi CGOC_0000345301 I
CRE21236 Caenorhabditis remanei CRE21236 I
DME_0000033301 Dracunculus medinensis DME_0000033301 N
GPUH_0001120501 Gongylonema pulchrum GPUH_0001120501 N
Hba_18627 Heterorhabditis bacteriophora Hba_18627 I
HPBE_0001384101 Heligmosomoides bakeri HPBE_0001384101 N
L889_g9935 Steinernema feltiae L889_g9935 N
L892_g11291 Steinernema scapterisci L892_g11291 N
L893_g17711 Steinernema glaseri L893_g17711 N
L898_g18025 Steinernema monticolum L898_g18025 N
MhA1_Contig468.frz3.gene12 Meloidogyne hapla MhA1_Contig468.frz3.gene12 N
Minc03820 Meloidogyne incognita Minc03820 N
nAv.1.0.1.g02361 Acanthocheilonema viteae nAv.1.0.1.g02361 N
nDi.2.2.2.g11238 Dirofilaria immitis nDi.2.2.2.g11238 I
NECAME_08042 Necator americanus NECAME_08042 N
nLs.2.1.2.g08792 Litomosoides sigmodontis nLs.2.1.2.g08792 N
OESDEN_01522 Oesophagostomum dentatum OESDEN_01522 N
OFLC_0000276401 Onchocerca flexuosa OFLC_0000276401 N
PPA12559 Pristionchus pacificus PPA12559 N
PTRK_0001041600 Parastrongyloides trichosuri PTRK_0001041600 N
RSKR_0000031900 Rhabditophanes kr3021 RSKR_0000031900 N
SPAL_0000348500 Strongyloides papillosus SPAL_0000348500 N
SVE_0177100 Strongyloides venezuelensis SVE_0177100 N
TCLT_0000958101 Thelazia callipaeda TCLT_0000958101 N
WBGene00242919 Onchocerca volvulus WBGene00242919 N
WUBG_06876 Wuchereria bancrofti WUBG_06876 N