nLs.2.1.2.g05605 (Litomosoides sigmodontis)
CBF/NF-Y

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF02045 (CBFB_NFYA) IPR001289 nLs.2.1.2.g05605 T160894_2.00 WormBase:ParaSite (2015-Oct-22)

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
NFYA
M08104_2.00
Homo sapiens
NSTGATTGGYB

VRCCAATCASN
ChIP-seq
Mathelier et al.(2014)
MA0060.3
0.857 0.857
NFYA
M09018_2.00
Homo sapiens
YKBYSATTGGYYRV

BYRRCCAATSRVMR
Misc
Kulakovskiy et al.(2013)
NFYA_HUMAN.H11MO.0.A
0.857 0.857
Nfya
M09019_2.00
Mus musculus
YKBYSATTGGYYRV

BYRRCCAATSRVMR
Misc
Kulakovskiy et al.(2013)
NFYA_MOUSE.H11MO.0.A
0.857 0.857
NFYA
M10403_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NFYA_02
0.857 0.857
NFYA
M10404_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NFYA_Q5
0.857 0.857
NFYA
M10405_2.00
Homo sapiens
NYTGATTGGYTAVH

DBTARCCAATCARN
Transfac
Matys et al.(2006)
V$NFY_C
0.857 0.857
HAP2
M08452_2.00
Saccharomyces cerevisiae
TTGGH

DCCAA
COMPILED
Mathelier et al.(2014)
MA0313.1
0.732 0.732
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
nLs.2.1.2.t05605-RA CBF/NF-Y 168 223

Links

Other CBF/NF-Y family TFs
Other Litomosoides sigmodontis TFs

269 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
WUBG_05875 Wuchereria bancrofti WUBG_05875 I 0.982
Bm6776 Brugia malayi Bm6776 I 0.982
LOAG_02863 Loa loa LOAG_02863 I 0.982
WBGene00242147 Onchocerca volvulus WBGene00242147 I 0.982
nAv.1.0.1.g00776 Acanthocheilonema viteae nAv.1.0.1.g00776 I 0.982
nDi.2.2.2.g05199 Dirofilaria immitis nDi.2.2.2.g05199 I 0.982
nOo.2.0.1.g03339 Onchocerca ochengi nOo.2.0.1.g03339 I 0.982
ALUE_0000650501 Ascaris lumbricoides ALUE_0000650501 I 0.964
ASU_03710 Ascaris suum ASU_03710 I 0.964
GPUH_0002134401 Gongylonema pulchrum GPUH_0002134401 I 0.964
TCNE_0001890401 Toxocara canis TCNE_0001890401 I 0.964
ASIM_0001003201 Anisakis simplex ASIM_0001003201 I 0.946
TCLT_0000871701 Thelazia callipaeda TCLT_0000871701 I 0.946
SBAD_0000676601 Soboliphyme baturini SBAD_0000676601 I 0.929
ENSMEUG00000005917 Macropus eugenii ENSMEUG00000005917 I 0.912
DME_0000143101 Dracunculus medinensis DME_0000143101 I 0.911
ENSEEUG00000006487 Erinaceus europaeus ENSEEUG00000006487 I 0.907
DAPPUDRAFT_300656 Daphnia pulex DAPPUDRAFT_300656 I 0.893
SPU_025589 Strongylocentrotus purpuratus SPU_025589 I 0.893
SPU_025737 Strongylocentrotus purpuratus SPU_025737 I 0.893
NFYA Anolis carolinensis ENSACAG00000016527 I 0.857
ENSAMEG00000004435 Ailuropoda melanoleuca ENSAMEG00000004435 I 0.857
ENSAPLG00000002694 Anas platyrhynchos ENSAPLG00000002694 I 0.857
NFYA Bos taurus ENSBTAG00000009905 I 0.857
NFYA Canis familiaris ENSCAFG00000001580 I 0.857
NFYA Callithrix jacchus ENSCJAG00000004074 I 0.857
NFYA Cavia porcellus ENSCPOG00000011146 I 0.857
ENSCSAG00000011196 Chlorocebus sabaeus ENSCSAG00000011196 I 0.857
NFYA Dasypus novemcinctus ENSDNOG00000039692 I 0.857
Nfya Dipodomys ordii ENSDORG00000006450 I 0.857
NFYA Equus caballus ENSECAG00000007952 I 0.857
ENSETEG00000000629 Echinops telfairi ENSETEG00000000629 I 0.857
ENSFALG00000002949 Ficedula albicollis ENSFALG00000002949 I 0.857
NFYA Felis catus ENSFCAG00000027813 I 0.857
NFYA Homo sapiens ENSG00000001167 D 0.857
NFYA Gallus gallus ENSGALG00000003247 I 0.857
NFYA Gorilla gorilla ENSGGOG00000008485 I 0.857
ENSLACG00000015334 Latimeria chalumnae ENSLACG00000015334 I 0.857
NFYA Loxodonta africana ENSLAFG00000016570 I 0.857
NFYA Meleagris gallopavo ENSMGAG00000010140 I 0.857
NFYA Myotis lucifugus ENSMLUG00000008253 I 0.857
NFYA Macaca mulatta ENSMMUG00000021173 I 0.857
NFYA Monodelphis domestica ENSMODG00000013084 I 0.857
ENSMPUG00000013686 Mustela putorius furo ENSMPUG00000013686 I 0.857
Nfya Mus musculus ENSMUSG00000023994 D 0.857
ENSNLEG00000005028 Nomascus leucogenys ENSNLEG00000005028 I 0.857
NFYA Ornithorhynchus anatinus ENSOANG00000011990 I 0.857
ENSOARG00000000894 Ovis aries ENSOARG00000000894 I 0.857
NFYA Oryctolagus cuniculus ENSOCUG00000016869 I 0.857
NFYA Otolemur garnettii ENSOGAG00000002636 I 0.857
ENSPANG00000009714 Papio anubis ENSPANG00000009714 I 0.857
NFYA Procavia capensis ENSPCAG00000011508 I 0.857
ENSPMAG00000000964 Petromyzon marinus ENSPMAG00000000964 I 0.857
ENSPPYG00000016588 Pongo abelii ENSPPYG00000016588 I 0.857
ENSPSIG00000013239 Pelodiscus sinensis ENSPSIG00000013239 I 0.857
NFYA Pan troglodytes ENSPTRG00000018146 I 0.857
NFYA Pteropus vampyrus ENSPVAG00000008318 I 0.857
Nfya Rattus norvegicus ENSRNOG00000012702 I 0.857
ENSSHAG00000017808 Sarcophilus harrisii ENSSHAG00000017808 I 0.857
ENSSSCG00000001600 Sus scrofa ENSSSCG00000001600 I 0.857
NFYA Sus scrofa ENSSSCG00000001611 I 0.857
ENSSSCG00000022941 Sus scrofa ENSSSCG00000022941 I 0.857
ENSSTOG00000023405 Ictidomys tridecemlineatus ENSSTOG00000023405 I 0.857
NFYA Taeniopygia guttata ENSTGUG00000001832 I 0.857
ENSTSYG00000007176 Tarsius syrichta ENSTSYG00000007176 I 0.857
NFYA Tursiops truncatus ENSTTRG00000013394 I 0.857
NFYA Vicugna pacos ENSVPAG00000008028 I 0.857
ISCW017122 Ixodes scapularis ISCW017122 I 0.857
Aan_R003793 Calypte anna Aan_R003793 I 0.857
Afo_R002068 Aptenodytes forsteri Afo_R002068 I 0.857
Alligator_sinensis_CCG020430.1 Alligator sinensis Alligator_sinensis_CCG020430.1 I 0.857
Brh_R001483 Buceros rhinoceros Brh_R001483 I 0.857
Cmyd_10011198 Chelonia mydas Cmyd_10011198 I 0.857
ENSP00000345702-D2 Bos grunniens ENSP00000345702-D2 I 0.857
ENSP00000345702 Macaca fascicularis ENSP00000345702 I 0.857
Myotis_brandtii_NFYA_10015424 Myotis brandtii Myotis_brandtii_NFYA_10015424 I 0.857
Pvit_06013 Pogona vitticeps Pvit_06013 I 0.857
Tal_R012767 Tyto alba Tal_R012767 I 0.857
estExt_fgenesh2_pg.C_2670023 Branchiostoma floridae estExt_fgenesh2_pg.C_2670023 I 0.857
fgenesh2_pg.scaffold_208000070 Branchiostoma floridae fgenesh2_pg.scaffold_208000070 I 0.857
Sakowv30001860m.g Saccoglossus kowalevskii Sakowv30001860m.g I 0.857
ANCCAN_07957 Ancylostoma caninum ANCCAN_07957 I 0.857
ANCCEY_15520 Ancylostoma ceylanicum ANCCEY_15520 I 0.857
ANCDUO_00071 Ancylostoma duodenale ANCDUO_00071 I 0.857
D915_02266 Fasciola hepatica D915_02266 I 0.857
DICVIV_12815 Dictyocaulus viviparus DICVIV_12815 I 0.857
HCOI00898900 Haemonchus contortus HCOI00898900 I 0.857
HPBE_0000764601 Heligmosomoides bakeri HPBE_0000764601 I 0.857
HPLM_0000552201 Haemonchus placei HPLM_0000552201 I 0.857
L596_g5816 Steinernema carpocapsae L596_g5816 I 0.857
L893_g18096 Steinernema glaseri L893_g18096 I 0.857
L898_g620 Steinernema monticolum L898_g620 I 0.857
NECAME_09605 Necator americanus NECAME_09605 I 0.857
TELCIR_00805 Teladorsagia circumcincta TELCIR_00805 I 0.857
CAOG_07995 Capsaspora owczarzaki CAOG_07995 I 0.839
ENSAMXG00000002532 Astyanax mexicanus ENSAMXG00000002532 I 0.839
ENSCING00000013482 Ciona intestinalis ENSCING00000013482 I 0.839
ENSCSAVG00000007408 Ciona savignyi ENSCSAVG00000007408 I 0.839
nfyal Danio rerio ENSDARG00000001621 I 0.839
nfya Danio rerio ENSDARG00000042004 I 0.839
nfyal Gasterosteus aculeatus ENSGACG00000007867 I 0.839
ENSGMOG00000001226 Gadus morhua ENSGMOG00000001226 I 0.839
ENSLOCG00000012292 Lepisosteus oculatus ENSLOCG00000012292 I 0.839
NFYA Microcebus murinus ENSMICG00000009686 I 0.839
nfyal Oryzias latipes ENSORLG00000006088 I 0.839
ENSPFOG00000012890 Poecilia formosa ENSPFOG00000012890 I 0.839
nfyal Tetraodon nigroviridis ENSTNIG00000015135 I 0.839
nfyal Takifugu rubripes ENSTRUG00000003925 I 0.839
ENSXMAG00000010069 Xiphophorus maculatus ENSXMAG00000010069 I 0.839
RPRC000951 Rhodnius prolixus RPRC000951 I 0.839
Smp_030250 Schistosoma mansoni Smp_030250 I 0.839
tetur23g00370 Tetranychus urticae tetur23g00370 I 0.839
AAI00179 Xenopus laevis AAI00179 I 0.839
HHAL009455-PA Halyomorpha halys HHAL009455-PA I 0.839
Sjc_0096630 Schistosoma japonicum Sjc_0096630 I 0.839
SMU15029949 Schmidtea mediterranea SMU15029949 I 0.839
nfya Xenopus tropicalis XB-GENE-942007 I 0.839
nfya.S Xenopus laevis XB-GENE-942013 I 0.839
A_04341 Schistosoma haematobium A_04341 I 0.839
csin107256 Clonorchis sinensis csin107256 I 0.839
ECPE_0000487901 Echinostoma caproni ECPE_0000487901 I 0.839
L889_g30157 Steinernema feltiae L889_g30157 I 0.839
L892_g3951 Steinernema scapterisci L892_g3951 I 0.839
maker-nMf.1.1.scaf00089-snap-gene-0.29 Meloidogyne floridensis maker-nMf.1.1.scaf00089-snap-gene-0.29 I 0.839
MhA1_Contig2248.frz3.gene3 Meloidogyne hapla MhA1_Contig2248.frz3.gene3 I 0.839
NBR_0000887901 Nippostrongylus brasiliensis NBR_0000887901 I 0.839
nRc.2.0.1.g32781 Romanomermis culicivorax nRc.2.0.1.g32781 I 0.839
OESDEN_02547 Oesophagostomum dentatum OESDEN_02547 I 0.839
OESDEN_11135 Oesophagostomum dentatum OESDEN_11135 I 0.839
SCUD_0001212601 Schistosoma curassoni SCUD_0001212601 I 0.839
SMRZ_0000504601 Schistosoma margrebowiei SMRZ_0000504601 I 0.839
SMTD_0000774701 Schistosoma mattheei SMTD_0000774701 I 0.839
SROB_0000925201 Schistosoma rodhaini SROB_0000925201 I 0.839
SSLN_0000312901 Schistocephalus solidus SSLN_0000312901 I 0.839
T265_04195 Opisthorchis viverrini T265_04195 I 0.839
TRE_0001025401 Trichobilharzia regenti TRE_0001025401 I 0.839
NFYA Sorex araneus ENSSARG00000009765 I 0.836
ACEP21720 Atta cephalotes ACEP21720 I 0.821
Aqu1.224085 Amphimedon queenslandica Aqu1.224085 I 0.821
CapteG223273 Capitella teleta CapteG223273 I 0.821
CGI_10002627 Crassostrea gigas CGI_10002627 I 0.821
CGI_10012001 Crassostrea gigas CGI_10012001 I 0.821
GB50732 Apis mellifera GB50732 I 0.821
HelroG146050 Helobdella robusta HelroG146050 I 0.821
NV16776 Nasonia vitripennis NV16776 I 0.821
PHUM011400 Pediculus humanus PHUM011400 I 0.821
SINV17788 Solenopsis invicta SINV17788 I 0.821
TC007453 Tribolium castaneum TC007453 I 0.821
YQE_10237 Dendroctonus ponderosae YQE_10237 I 0.821
Cflo_01621--XP_001121566.1_APIME Camponotus floridanus Cflo_01621--XP_001121566.1_APIME I 0.821
Hsal_09569--XP_001121566.1_APIME Harpegnathos saltator Hsal_09569--XP_001121566.1_APIME I 0.821
LDEC000161 Leptinotarsa decemlineata LDEC000161 I 0.821
SMU15024997 Schmidtea mediterranea SMU15024997 I 0.821
PXEA_0001432401 Protopolystoma xenopodis PXEA_0001432401 I 0.820
Nf-YA Drosophila melanogaster FBgn0035993 I 0.815
GA17755 Drosophila pseudoobscura FBgn0077764 I 0.815
GF24667 Drosophila ananassae FBgn0101660 I 0.815
GG14038 Drosophila erecta FBgn0106300 I 0.815
GH15528 Drosophila grimshawi FBgn0123000 I 0.815
GI16805 Drosophila mojavensis FBgn0139552 I 0.815
GJ12551 Drosophila virilis FBgn0199791 I 0.815
GE21241 Drosophila yakuba FBgn0238513 I 0.815
CpipJ_CPIJ010764 Culex pipiens CpipJ_CPIJ010764 I 0.804
CpipJ_CPIJ017497 Culex pipiens CpipJ_CPIJ017497 I 0.804
ACYPI008647 Acyrthosiphon pisum ACYPI008647 I 0.804
AGAP007376 Anopheles gambiae AGAP007376 I 0.804
CPIJ010764 Culex quinquefasciatus CPIJ010764 I 0.804
CPIJ017497 Culex quinquefasciatus CPIJ017497 I 0.804
LotgiG159581 Lottia gigantea LotgiG159581 I 0.804
LotgiG96004 Lottia gigantea LotgiG96004 I 0.804
MESCA012339 Megaselia scalaris MESCA012339 I 0.804
ML027313a Mnemiopsis leidyi ML027313a I 0.804
Ocbimv22031841m.g Octopus bimaculoides Ocbimv22031841m.g I 0.804
Sakowv30044373m.g Saccoglossus kowalevskii Sakowv30044373m.g I 0.804
AALB004535 Anopheles albimanus AALB004535 I 0.804
MDOA015095 Musca domestica MDOA015095 I 0.804
GPLIN_001226400 Globodera pallida GPLIN_001226400 I 0.804
Hba_19892 Heterorhabditis bacteriophora Hba_19892 I 0.804
MCOS_0000435001 Mesocestoides corti MCOS_0000435001 I 0.804
TMUE_s0062005000 Trichuris muris TMUE_s0062005000 I 0.804
TsM_000826500 Taenia solium TsM_000826500 I 0.804
TTAC_0000640001 Hydatigera taeniaeformis TTAC_0000640001 I 0.804
ACOC_0000844001 Angiostrongylus costaricensis ACOC_0000844001 I 0.796
ACYPI48827 Acyrthosiphon pisum ACYPI48827 I 0.786
GLOINDRAFT_349601 Rhizophagus irregularis GLOINDRAFT_349601 I 0.786
Ocbimv22027261m.g Octopus bimaculoides Ocbimv22027261m.g I 0.786
SNAPOd2T00008768001 Oikopleura dioica SNAPOd2T00008768001 I 0.786
ACUA028400 Anopheles culicifacies ACUA028400 I 0.786
PPAI000251 Phlebotomus papatasi PPAI000251 I 0.786
D918_06860 Trichuris suis D918_06860 I 0.786
HDID_0001056801 Hymenolepis diminuta HDID_0001056801 I 0.786
HmN_000419600 Hymenolepis microstoma HmN_000419600 I 0.786
HNAJ_0000223001 Hymenolepis nana HNAJ_0000223001 I 0.786
TTRE_0000464501 Trichuris trichiura TTRE_0000464501 I 0.786
ECANG7_02027 Echinococcus canadensis ECANG7_02027 I 0.780
EmuJ_001061700 Echinococcus multilocularis EmuJ_001061700 I 0.780
CLEC007231 Cimex lectularius CLEC007231 I 0.774
AMAM001825 Anopheles maculatus AMAM001825 I 0.771
NEMVEDRAFT_v1g248844 Nematostella vectensis NEMVEDRAFT_v1g248844 I 0.768
NEMVEDRAFT_v1g82757 Nematostella vectensis NEMVEDRAFT_v1g82757 I 0.768
Gfo_R002980 Geospiza fortis Gfo_R002980 I 0.768
scaffold5-EXSNAP2012.16 Pristionchus exspectatus scaffold5-EXSNAP2012.16 I 0.768
SMUV_0000428301 Syphacia muris SMUV_0000428301 I 0.768
BOTBODRAFT_182611 Botryobasidium botryosum BOTBODRAFT_182611 I 0.750
CAGL0H07843g Candida glabrata CAGL0H07843g I 0.750
nfyA Dictyostelium discoideum DDB_G0282697 I 0.750
KGM_14733 Danaus plexippus KGM_14733 I 0.750
RHTO_00634 Rhodosporidium toruloides RHTO_00634 I 0.750
RTG_01693 Rhodotorula glutinis RTG_01693 I 0.750
TriadG58635 Trichoplax adhaerens TriadG58635 I 0.750
V565_064680 Rhizoctonia solani V565_064680 I 0.750
estExt_fgenesh1_pg.C_120063 Sporobolomyces roseus estExt_fgenesh1_pg.C_120063 I 0.750
fgeneshMC_pg.10_#_374 Mucor circinelloides fgeneshMC_pg.10_#_374 I 0.750
PTRK_0000025200 Parastrongyloides trichosuri PTRK_0000025200 N 0.750
SPAL_0000205900 Strongyloides papillosus SPAL_0000205900 N 0.750
SSTP_0000922000 Strongyloides stercoralis SSTP_0000922000 N 0.750
SVE_0978200 Strongyloides venezuelensis SVE_0978200 N 0.750
ADAC005077 Anopheles darlingi ADAC005077 I 0.745
AARA007990 Anopheles arabiensis AARA007990 I 0.745
AATE016159 Anopheles atroparvus AATE016159 I 0.745
ACHR000726 Anopheles christyi ACHR000726 I 0.745
ACOM025626 Anopheles coluzzii ACOM025626 I 0.745
AFUN002061 Anopheles funestus AFUN002061 I 0.745
AMEC004928 Anopheles melas AMEC004928 I 0.745
AMEM003440 Anopheles merus AMEM003440 I 0.745
AQUA004503 Anopheles quadriannulatus AQUA004503 I 0.745
ASTEI01331 Anopheles stephensi ASTEI01331 I 0.745
EVEC_0000960901 Enterobius vermicularis EVEC_0000960901 N 0.744
DACRYDRAFT_48176 Dacryopinax sp DACRYDRAFT_48176 I 0.732
KNAG_0I00270 Kazachstania naganishii KNAG_0I00270 I 0.732
ML45131a Mnemiopsis leidyi ML45131a I 0.732
NDAI_0I03200 Naumovozyma dairenensis NDAI_0I03200 I 0.732
SKUD_123802 Saccharomyces kudriavzevii SKUD_123802 I 0.732
SU7_1051 Saccharomyces arboricola SU7_1051 I 0.732
TDEL_0D06280 Torulaspora delbrueckii TDEL_0D06280 I 0.732
HAP2 Saccharomyces cerevisiae YGL237C D 0.732
estExt_fgenesh2_pg.C_Chr_130205 Micromonas sp RCC299 estExt_fgenesh2_pg.C_Chr_130205 N 0.732
6941_YGL237C Saccharomyces mikatae 6941_YGL237C I 0.732
7676_YGL237C Saccharomyces paradoxus 7676_YGL237C I 0.732
7831_YGL237C Saccharomyces bayanus 7831_YGL237C I 0.732
MDP0000183865 Malus domestica MDP0000183865 I 0.727
AMIN010496 Anopheles minimus AMIN010496 I 0.725
Ppa-nfya-1 Pristionchus pacificus PPA20666 N 0.721
OESDEN_02553 Oesophagostomum dentatum OESDEN_02553 N 0.717
AMAG_13560 Allomyces macrogynus AMAG_13560 I 0.714
AMAG_13812 Allomyces macrogynus AMAG_13812 I 0.714
RO3G_00980 Rhizopus oryzae RO3G_00980 I 0.714
RO3G_16178 Rhizopus oryzae RO3G_16178 I 0.714
AACERI_AaceriAFR257W Saccharomycetaceae sp ashbya aceri AACERI_AaceriAFR257W I 0.714
AGOS_AFR257W Ashbya gossypii AGOS_AFR257W I 0.714
AWRI1499_3546 Brettanomyces bruxellensis AWRI1499_3546 I 0.714
BN946_scf184796.g4 Trametes cinnabarina BN946_scf184796.g4 I 0.714
GLOTRDRAFT_21409 Gloeophyllum trabeum GLOTRDRAFT_21409 I 0.714
J056_003714 Wallemia ichthyophaga J056_003714 I 0.714
JAAARDRAFT_97747 Jaapia argillacea JAAARDRAFT_97747 I 0.714
KAFR_0J02840 Kazachstania africana KAFR_0J02840 I 0.714
KLLA0_A00891g Kluyveromyces lactis KLLA0_A00891g I 0.714
LALA0_S06e08218g Lachancea lanzarotensis LALA0_S06e08218g I 0.714
NCAS_0E00300 Naumovozyma castellii NCAS_0E00300 I 0.714
SCHCODRAFT_110229 Schizophyllum commune SCHCODRAFT_110229 I 0.714
WALSEDRAFT_57633 Wallemia sebi WALSEDRAFT_57633 I 0.714
ZYRO0E09372g Zygosaccharomyces rouxii ZYRO0E09372g I 0.714
EuGene.0000150165 Micromonas pusilla EuGene.0000150165 N 0.714
fgeneshMC_pg.11_#_166 Mucor circinelloides fgeneshMC_pg.11_#_166 I 0.714
Scas_Contig712.15 Saccharomyces castellii Scas_Contig712.15 I 0.714
SAKL0F00990g Lachancea kluyveri SAKL0F00990g I 0.714
SVUK_0001685001 Strongylus vulgaris SVUK_0001685001 N 0.710
SPPG_06102 Spizellomyces punctatus SPPG_06102 I 0.709
AFAF018449 Anopheles farauti AFAF018449 I 0.706