unc-3 (Caenorhabditis elegans)
EBF1

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF16422 (COE1_DBD) (none) WBGene00006743 T174782_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; histone acetyltransferase binding activity; and identical protein binding activity. Involved in several processes, including axon guidance; dauer larval development; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in ABalappaap; ABalappaapp; and neurons. Orthologous to several human genes including EBF3 (EBF transcription factor 3). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
kn
M03721_2.00 		Drosophila melanogaster
BWATTCCCHDGGGAATWV
BWATTCCCHDGGGAATWV		 SELEX
Nitta et al.(2015)
kn_1 		0.730 0.730
Ebf1
M09045_2.00 		Mus musculus
DBYCCCWRGGGAV
BTCCCYWGGGRVH		 Misc
Kulakovskiy et al.(2013)
COE1_MOUSE.H11MO.0.A 		0.730 0.730
Ebf1
M09527_2.00 		Mus musculus
DBTCCCHDGGGA
TCCCHDGGGAVH		 Misc
Heinz et al.(2010)
proBcell-EBF_GSE21978 		0.730 0.730
Ebf1
M10469_2.00 		Mus musculus
VYMHVYYCYYBRGGGAVTHKHB
VDMDABTCCCYVRRGRRBDKRB		 Transfac
Matys et al.(2006)
V$OLF1_01 		0.730 0.730
EBF4
M10460_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EBF4_02 		0.721 0.721
Ebf4
M10468_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EBF4_01 		0.716 0.716
EBF3
M10461_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$EBF_Q6 		0.716 0.716
Ebf2
M10467_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$COE2_01 		0.703 0.703
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
Y16B4A.1 EBF1 27 250

Links

Other EBF1 family TFs
Other Caenorhabditis elegans TFs

189 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CRE15310 Caenorhabditis remanei CRE15310 I 0.905
CBN13270 Caenorhabditis brenneri CBN13270 I 0.901
CBG07590 Caenorhabditis briggsae CBG07590 I 0.878
ASU_01180 Ascaris suum ASU_01180 I 0.815
Bm6296 Brugia malayi Bm6296 I 0.811
nDi.2.2.2.g04990 Dirofilaria immitis nDi.2.2.2.g04990 I 0.802
nAv.1.0.1.g03521 Acanthocheilonema viteae nAv.1.0.1.g03521 I 0.802
LOAG_18199 Loa loa LOAG_18199 I 0.802
WBGene00240610 Onchocerca volvulus WBGene00240610 I 0.797
nLs.2.1.2.g08363 Litomosoides sigmodontis nLs.2.1.2.g08363 I 0.797
HPLM_0000807901 Haemonchus placei HPLM_0000807901 I 0.793
HCOI01630600 Haemonchus contortus HCOI01630600 I 0.793
WUBG_00630 Wuchereria bancrofti WUBG_00630 I 0.793
NECAME_10162 Necator americanus NECAME_10162 I 0.793
SVUK_0001114801 Strongylus vulgaris SVUK_0001114801 I 0.793
TCLT_0000613901 Thelazia callipaeda TCLT_0000613901 I 0.788
DME_0000265301 Dracunculus medinensis DME_0000265301 I 0.784
L898_g8304 Steinernema monticolum L898_g8304 I 0.770
L889_g1820 Steinernema feltiae L889_g1820 I 0.770
PTRK_0001642500 Parastrongyloides trichosuri PTRK_0001642500 I 0.766
L596_g20342 Steinernema carpocapsae L596_g20342 I 0.766
nRc.2.0.1.g06532 Romanomermis culicivorax nRc.2.0.1.g06532 I 0.766
D917_06660 Trichinella nativa D917_06660 I 0.757
L893_g31120 Steinernema glaseri L893_g31120 I 0.757
SSTP_0000472000 Strongyloides stercoralis SSTP_0000472000 I 0.757
EFV50386 Trichinella spiralis EFV50386 I 0.757
NV10306 Nasonia vitripennis NV10306 I 0.757
SPAL_0001132500 Strongyloides papillosus SPAL_0001132500 I 0.752
SVE_0119400 Strongyloides venezuelensis SVE_0119400 I 0.752
CGI_10023990 Crassostrea gigas CGI_10023990 I 0.748
TTRE_0000372001 Trichuris trichiura TTRE_0000372001 I 0.748
PHUM119360 Pediculus humanus PHUM119360 I 0.743
AAEL003436 Aedes aegypti AAEL003436 I 0.739
kn Drosophila melanogaster FBgn0001319 D 0.739
MDOA011385 Musca domestica MDOA011385 I 0.734
ENSFALG00000008502 Ficedula albicollis ENSFALG00000008502 I 0.734
EBF1 Gallus gallus ENSGALG00000003699 I 0.734
ENSLOCG00000009282 Lepisosteus oculatus ENSLOCG00000009282 I 0.734
ebf1a Danio rerio ENSDARG00000099849 I 0.734
ENSPPYG00000015995 Pongo abelii ENSPPYG00000015995 I 0.730
GE12286 Drosophila yakuba FBgn0230042 I 0.730
GA24435 Drosophila pseudoobscura FBgn0245832 I 0.730
GK23295 Drosophila willistoni FBgn0225257 I 0.730
EBF1 Bos taurus ENSBTAG00000037508 I 0.730
GL10656 Drosophila persimilis FBgn0148266 I 0.730
EBF1 Pan troglodytes ENSPTRG00000017477 I 0.730
ENSPFOG00000000294 Poecilia formosa ENSPFOG00000000294 I 0.730
EBF4 Monodelphis domestica ENSMODG00000005256 I 0.730
EBF1 Ornithorhynchus anatinus ENSOANG00000012338 I 0.730
SPU_004702 Strongylocentrotus purpuratus SPU_004702 I 0.730
Ebf1 Mus musculus ENSMUSG00000057098 D 0.730
ENSONIG00000017655 Oreochromis niloticus ENSONIG00000017655 I 0.730
EBF1 Monodelphis domestica ENSMODG00000008198 I 0.730
EBF1 Oryzias latipes ENSORLG00000007471 I 0.730
Ebf1 Rattus norvegicus ENSRNOG00000028845 I 0.730
GM20182 Drosophila sechellia FBgn0175065 I 0.730
ENSGACG00000010053 Gasterosteus aculeatus ENSGACG00000010053 I 0.730
GG22397 Drosophila erecta FBgn0114569 I 0.730
ENSSHAG00000017239 Sarcophilus harrisii ENSSHAG00000017239 I 0.730
EBF1 Homo sapiens ENSG00000164330 D 0.730
EBF1 Callithrix jacchus ENSCJAG00000019016 I 0.730
AGAP011437 Anopheles gambiae AGAP011437 I 0.730
EBF1 Echinops telfairi ENSETEG00000011711 I 0.730
EBF1 Gorilla gorilla ENSGGOG00000000033 I 0.730
ENSONIG00000004376 Oreochromis niloticus ENSONIG00000004376 I 0.725
ENSAMEG00000006442 Ailuropoda melanoleuca ENSAMEG00000006442 I 0.725
KGM_09934 Danaus plexippus KGM_09934 I 0.725
ebf1b Danio rerio ENSDARG00000069196 I 0.725
L798_15574 Zootermopsis nevadensis L798_15574 I 0.725
ENSAMXG00000003402 Astyanax mexicanus ENSAMXG00000003402 I 0.725
EBF1 Takifugu rubripes ENSTRUG00000009320 I 0.725
GB42304 Apis mellifera GB42304 I 0.725
ENSLOCG00000001693 Lepisosteus oculatus ENSLOCG00000001693 I 0.725
EBF1 Loxodonta africana ENSLAFG00000017522 I 0.725
GH20479 Drosophila grimshawi FBgn0127942 I 0.725
GF11778 Drosophila ananassae FBgn0088818 I 0.725
GJ21945 Drosophila virilis FBgn0209060 I 0.725
EBF1 Gasterosteus aculeatus ENSGACG00000018450 I 0.725
CapteG93575 Capitella teleta CapteG93575 I 0.721
EBF4 Otolemur garnettii ENSOGAG00000004688 I 0.721
EBF4 Tursiops truncatus ENSTTRG00000003459 I 0.721
ENSPPYG00000010836 Pongo abelii ENSPPYG00000010836 I 0.721
ENSSSCG00000010757 Sus scrofa ENSSSCG00000010757 I 0.721
ENSAMEG00000011229 Ailuropoda melanoleuca ENSAMEG00000011229 I 0.721
EBF4 Gorilla gorilla ENSGGOG00000015503 I 0.721
BXY_1639700 Bursaphelenchus xylophilus BXY_1639700 I 0.721
EBF4 Myotis lucifugus ENSMLUG00000023832 I 0.721
ENSGMOG00000015541 Gadus morhua ENSGMOG00000015541 I 0.721
EBF4 Bos taurus ENSBTAG00000037757 I 0.721
ebf4 Xenopus tropicalis XB-GENE-6030626 I 0.721
Pvit_16838 Pogona vitticeps Pvit_16838 I 0.721
EBF4 Canis familiaris ENSCAFG00000006631 I 0.721
ENSMPUG00000009093 Mustela putorius furo ENSMPUG00000009093 I 0.721
TC001270 Tribolium castaneum TC001270 I 0.721
EBF4 Equus caballus ENSECAG00000010003 I 0.721
EBF4 Homo sapiens ENSG00000088881 D 0.721
Ebf3 Rattus norvegicus ENSRNOG00000016102 I 0.716
EBF1 Takifugu rubripes ENSTRUG00000013805 I 0.716
ENSXMAG00000006633 Xiphophorus maculatus ENSXMAG00000006633 I 0.716
ENSXMAG00000010668 Xiphophorus maculatus ENSXMAG00000010668 I 0.716
EBF3 Cavia porcellus ENSCPOG00000005096 I 0.716
ENSPSIG00000016691 Pelodiscus sinensis ENSPSIG00000016691 I 0.716
EBF1 Canis familiaris ENSCAFG00000017318 I 0.716
EBF3 Homo sapiens ENSG00000108001 D 0.716
EBF3 Taeniopygia guttata ENSTGUG00000011600 I 0.716
EBF1 Cavia porcellus ENSCPOG00000026184 I 0.716
ENSXMAG00000000489 Xiphophorus maculatus ENSXMAG00000000489 I 0.716
ENSONIG00000019141 Oreochromis niloticus ENSONIG00000019141 I 0.716
EBF1 Oryzias latipes ENSORLG00000002342 I 0.716
Ebf3 Mus musculus ENSMUSG00000010476 I 0.716
Ebf4 Mus musculus ENSMUSG00000053552 D 0.716
EBF3 Anolis carolinensis ENSACAG00000008590 I 0.716
ENSFALG00000001212 Ficedula albicollis ENSFALG00000001212 I 0.716
LotgiG225788 Lottia gigantea LotgiG225788 I 0.716
EBF1 Oryctolagus cuniculus ENSOCUG00000008985 I 0.716
EBF3 Otolemur garnettii ENSOGAG00000007572 I 0.716
EBF4 Oryzias latipes ENSORLG00000020414 I 0.716
Cmyd_10020950 Chelonia mydas Cmyd_10020950 I 0.716
ENSPPYG00000002766 Pongo abelii ENSPPYG00000002766 I 0.716
ENSPFOG00000002559 Poecilia formosa ENSPFOG00000002559 I 0.716
EBF3 Macaca mulatta ENSMMUG00000011447 I 0.716
Myotis_brandtii_EBF4_10032372 Myotis brandtii Myotis_brandtii_EBF4_10032372 I 0.712
ebf3 Xenopus tropicalis XB-GENE-962543 I 0.712
ENSXMAG00000012715 Xiphophorus maculatus ENSXMAG00000012715 I 0.712
Aan_R007097 Calypte anna Aan_R007097 I 0.712
ENSP00000405003 Macaca fascicularis ENSP00000405003 I 0.712
GI21022 Drosophila mojavensis FBgn0143754 I 0.712
ebf2 Oryzias latipes ENSORLG00000006408 I 0.712
ENSONIG00000008631 Oreochromis niloticus ENSONIG00000008631 I 0.712
ENSONIG00000000451 Oreochromis niloticus ENSONIG00000000451 I 0.712
ENSONIG00000013342 Oreochromis niloticus ENSONIG00000013342 I 0.712
ebf3a Oryzias latipes ENSORLG00000005870 I 0.712
ENSPFOG00000009617 Poecilia formosa ENSPFOG00000009617 I 0.712
EBF3 Tursiops truncatus ENSTTRG00000014010 I 0.712
ENSLOCG00000007615 Lepisosteus oculatus ENSLOCG00000007615 I 0.712
ebf3a Danio rerio ENSDARG00000100244 I 0.712
ENSAMXG00000006585 Astyanax mexicanus ENSAMXG00000006585 I 0.712
EBF1 Gasterosteus aculeatus ENSGACG00000020458 I 0.712
ENSGMOG00000016636 Gadus morhua ENSGMOG00000016636 I 0.712
ENSLACG00000017271 Latimeria chalumnae ENSLACG00000017271 I 0.712
ENSPFOG00000017183 Poecilia formosa ENSPFOG00000017183 I 0.712
EBF1 Microcebus murinus ENSMICG00000010036 I 0.712
ENSPSIG00000016837 Pelodiscus sinensis ENSPSIG00000016837 I 0.712
EBF1 Taeniopygia guttata ENSTGUG00000000593 I 0.712
EBF2 Taeniopygia guttata ENSTGUG00000004267 I 0.707
EBF2 Gallus gallus ENSGALG00000000242 I 0.707
ebf3.L Xenopus laevis XB-GENE-962547 I 0.707
ebf2.L Xenopus laevis XB-GENE-6252857 I 0.707
ebf2 Tetraodon nigroviridis ENSTNIG00000015845 I 0.707
ENSLOCG00000015225 Lepisosteus oculatus ENSLOCG00000015225 I 0.707
ebf2 Gasterosteus aculeatus ENSGACG00000008451 I 0.707
ebf2 Takifugu rubripes ENSTRUG00000011528 I 0.707
ENSAMEG00000003291 Ailuropoda melanoleuca ENSAMEG00000003291 I 0.707
ENSAPLG00000009260 Anas platyrhynchos ENSAPLG00000009260 I 0.707
ebf3a Takifugu rubripes ENSTRUG00000005721 I 0.707
EBF2 Meleagris gallopavo ENSMGAG00000000791 I 0.707
ENSFALG00000011234 Ficedula albicollis ENSFALG00000011234 I 0.707
ebf3a Gasterosteus aculeatus ENSGACG00000009548 I 0.707
ebf2 Xenopus tropicalis XB-GENE-971136 I 0.707
Afo_R003215 Aptenodytes forsteri Afo_R003215 I 0.707
ENSSTOG00000006113 Ictidomys tridecemlineatus ENSSTOG00000006113 I 0.707
ebf2 Danio rerio ENSDARG00000042525 I 0.703
EBF2 Cavia porcellus ENSCPOG00000001463 I 0.703
EBF2 Pteropus vampyrus ENSPVAG00000024254 I 0.703
EBF2 Dasypus novemcinctus ENSDNOG00000040488 I 0.703
ENSCING00000003209 Ciona intestinalis ENSCING00000003209 I 0.703
EBF2 Equus caballus ENSECAG00000014179 I 0.703
EBF2 Bos taurus ENSBTAG00000040390 I 0.703
ENSAMEG00000000326 Ailuropoda melanoleuca ENSAMEG00000000326 I 0.703
DAPPUDRAFT_22285 Daphnia pulex DAPPUDRAFT_22285 I 0.703
ENSPANG00000020231 Papio anubis ENSPANG00000020231 I 0.703
HelroG112029 Helobdella robusta HelroG112029 I 0.703
Ebf2 Rattus norvegicus ENSRNOG00000011548 I 0.703
EBF2 Pan troglodytes ENSPTRG00000003058 I 0.703
EBF2 Canis familiaris ENSCAFG00000008918 I 0.703
EBF2 Homo sapiens ENSG00000221818 D 0.703
Ebf2 Mus musculus ENSMUSG00000022053 D 0.703
ENSPPYG00000018454 Pongo abelii ENSPPYG00000018454 I 0.703
EBF2 Loxodonta africana ENSLAFG00000022465 I 0.703
ENSMPUG00000003195 Mustela putorius furo ENSMPUG00000003195 I 0.703
EBF2 Myotis lucifugus ENSMLUG00000011509 I 0.703
ENSNLEG00000016189 Nomascus leucogenys ENSNLEG00000016189 I 0.703
ENSXMAG00000017859 Xiphophorus maculatus ENSXMAG00000017859 I 0.703
EBF2 Otolemur garnettii ENSOGAG00000010783 I 0.703
EBF2 Sus scrofa ENSSSCG00000009655 I 0.703
EBF2 Oryctolagus cuniculus ENSOCUG00000011972 I 0.703
ENSOARG00000009825 Ovis aries ENSOARG00000009825 I 0.703
EBF2 Gorilla gorilla ENSGGOG00000001585 I 0.703
EBF1 Felis catus ENSFCAG00000008547 I 0.703