NKX6-1 (Choloepus hoffmanni)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSCHOG00000005454 T207762_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Nkx6-1
M00466_2.00 		Mus musculus
NDTDATNRN
NYNATHAHN		 PBM
Berger et al.(2008)
Nkx6-1_2825 		0.360 1.000
NKX6-1
M09151_2.00 		Homo sapiens
RAHWRATKDSNWWWTRATD
HATYAWWWNSHMATYWDTY		 Misc
Kulakovskiy et al.(2013)
NKX61_HUMAN.H11MO.0.B 		0.360 1.000
Nkx6-1
M09200_2.00 		Mus musculus
HNWRATKDNHWWWTRATDR
YHATYAWWWDNHMATYWND		 Misc
Kulakovskiy et al.(2013)
NKX61_MOUSE.H11MO.0.A 		0.360 1.000
Nkx6-1
M09573_2.00 		Mus musculus
NDTAATKR
YMATTAHN		 Misc
Heinz et al.(2010)
Islet-Nkx6.1_GSE40975 		0.360 1.000
NKX6-1
M10718_2.00 		Homo sapiens
HWTTTAATKGRWT
AWYCMATTAAAWD		 Transfac
Matys et al.(2006)
V$NKX61_01 		0.360 1.000
NKX6-1
M10719_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$NKX61_08 		0.360 1.000
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSCHOP00000004825 Homeodomain 239 283

Links

Other Homeodomain family TFs
Other Choloepus hoffmanni TFs

132 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSMICG00000006922 Microcebus murinus ENSMICG00000006922 I 0.867
ENSMEUG00000009353 Macropus eugenii ENSMEUG00000009353 I 0.858
ENSECAG00000018325 Equus caballus ENSECAG00000018325 I 0.849
ENSOANG00000006212 Ornithorhynchus anatinus ENSOANG00000006212 I 0.849
ENSPFOG00000002761 Poecilia formosa ENSPFOG00000002761 I 0.849
NKX6-1 Sus scrofa ENSSSCG00000009232 I 0.849
Myotis_brandtii_NKX6_10030510 Myotis brandtii Myotis_brandtii_NKX6_10030510 N 0.849
ENSAPLG00000005538 Anas platyrhynchos ENSAPLG00000005538 I 0.840
NKX6-2 Procavia capensis ENSPCAG00000000708 N 0.840
ENSSHAG00000002937 Sarcophilus harrisii ENSSHAG00000002937 I 0.840
Gfo_R008628 Geospiza fortis Gfo_R008628 I 0.840
CpipJ_CPIJ001377 Culex pipiens CpipJ_CPIJ001377 N 0.837
AAEL004033 Aedes aegypti AAEL004033 N 0.837
ACEP17328 Atta cephalotes ACEP17328 N 0.837
BGIBMGA010051 Bombyx mori BGIBMGA010051 N 0.837
CapteG6193 Capitella teleta CapteG6193 N 0.837
CPIJ001377 Culex quinquefasciatus CPIJ001377 N 0.837
KGM_13904 Danaus plexippus KGM_13904 N 0.837
MCINX004710 Melitaea cinxia MCINX004710 N 0.837
PHUM359870 Pediculus humanus PHUM359870 N 0.837
SINV25324 Solenopsis invicta SINV25324 I 0.837
YQE_09155 Dendroctonus ponderosae YQE_09155 N 0.837
Hsal_06171--XP_001121097.1_APIME Harpegnathos saltator Hsal_06171--XP_001121097.1_APIME N 0.837
Ocbimv22025901m.g Octopus bimaculoides Ocbimv22025901m.g N 0.837
CLEC002616 Cimex lectularius CLEC002616 N 0.837
HHAL007703-PA Halyomorpha halys HHAL007703-PA N 0.837
LCUP008694 Lucilia cuprina LCUP008694 N 0.837
LDEC017209 Leptinotarsa decemlineata LDEC017209 N 0.837
Sjc_0111830 Schistosoma japonicum Sjc_0111830 N 0.837
AALB008452 Anopheles albimanus AALB008452 N 0.837
AATE008437 Anopheles atroparvus AATE008437 N 0.837
ACUA026159 Anopheles culicifacies ACUA026159 N 0.837
ADIR006386 Anopheles dirus ADIR006386 N 0.837
AEPI002734 Anopheles epiroticus AEPI002734 N 0.837
AFAF005788 Anopheles farauti AFAF005788 N 0.837
AMAM013696 Anopheles maculatus AMAM013696 N 0.837
AMEC022035 Anopheles melas AMEC022035 N 0.837
AMEM013182 Anopheles merus AMEM013182 N 0.837
AQUA009532 Anopheles quadriannulatus AQUA009532 N 0.837
ASIS022603 Anopheles sinensis ASIS022603 N 0.837
PPAI007703 Phlebotomus papatasi PPAI007703 N 0.837
A_02867 Schistosoma haematobium A_02867 N 0.837
ECPE_0000358001 Echinostoma caproni ECPE_0000358001 N 0.837
SCUD_0002097601 Schistosoma curassoni SCUD_0002097601 N 0.837
SROB_0001257001 Schistosoma rodhaini SROB_0001257001 N 0.837
PXEA_0000446101 Protopolystoma xenopodis PXEA_0000446101 N 0.835
ISCW014430 Ixodes scapularis ISCW014430 N 0.820
D917_05078 Trichinella nativa D917_05078 N 0.814
D917_08408 Trichinella nativa D917_08408 N 0.814
WUBG_08661 Wuchereria bancrofti WUBG_08661 N 0.812
ANCDUO_24100 Ancylostoma duodenale ANCDUO_24100 N 0.794
ASIM_0001695301 Anisakis simplex ASIM_0001695301 N 0.794
DICVIV_02945 Dictyocaulus viviparus DICVIV_02945 N 0.794
TCNE_0001839401 Toxocara canis TCNE_0001839401 N 0.794
TRE_0000644601 Trichobilharzia regenti TRE_0000644601 N 0.790
nRc.2.0.1.g06912 Romanomermis culicivorax nRc.2.0.1.g06912 N 0.784
nLs.2.1.2.g06018 Litomosoides sigmodontis nLs.2.1.2.g06018 N 0.779
AMIN002697 Anopheles minimus AMIN002697 N 0.775
augustus_masked-nMf.1.1.scaf02139-processed-gene-0.0 Meloidogyne floridensis augustus_masked-nMf.1.1.scaf02139-processed-gene-0.0 N 0.773
Afo_R002915 Aptenodytes forsteri Afo_R002915 N 0.756
Ppa-cog-1 Pristionchus pacificus PPA04716 N 0.747
EVEC_0000660801 Enterobius vermicularis EVEC_0000660801 N 0.747
Bm5188 Brugia malayi Bm5188 N 0.732
OFLC_0001516501 Onchocerca flexuosa OFLC_0001516501 N 0.732
scaffold37-EXSNAP2012.8 Pristionchus exspectatus scaffold37-EXSNAP2012.8 N 0.726
ENSOARG00000007317 Ovis aries ENSOARG00000007317 N 0.656
MESCA000156 Megaselia scalaris MESCA000156 I 0.617
nOo.2.0.1.g02038 Onchocerca ochengi nOo.2.0.1.g02038 I 0.606
CpipJ_CPIJ001077 Culex pipiens CpipJ_CPIJ001077 I 0.601
CPIJ001077 Culex quinquefasciatus CPIJ001077 I 0.601
ISCW002094 Ixodes scapularis ISCW002094 I 0.601
RPRC003712 Rhodnius prolixus RPRC003712 I 0.601
CLEC013163 Cimex lectularius CLEC013163 I 0.601
HHAL002696-PA Halyomorpha halys HHAL002696-PA I 0.601
LCUP012257 Lucilia cuprina LCUP012257 I 0.601
AARA011457 Anopheles arabiensis AARA011457 I 0.601
AFUN008465 Anopheles funestus AFUN008465 I 0.601
AMEC008489 Anopheles melas AMEC008489 I 0.601
ASIS009140 Anopheles sinensis ASIS009140 I 0.601
ENSAMEG00000003692 Ailuropoda melanoleuca ENSAMEG00000003692 I 0.360
ENSAMXG00000001095 Astyanax mexicanus ENSAMXG00000001095 I 0.360
NKX6-1 Bos taurus ENSBTAG00000002518 I 0.360
NKX6-1 Canis familiaris ENSCAFG00000009157 I 0.360
NKX6-1 Callithrix jacchus ENSCJAG00000005335 I 0.360
ENSCPOG00000026192 Cavia porcellus ENSCPOG00000026192 I 0.360
ENSCSAG00000004373 Chlorocebus sabaeus ENSCSAG00000004373 I 0.360
nkx6.1 Danio rerio ENSDARG00000022569 I 0.360
NKX6-1 Dasypus novemcinctus ENSDNOG00000014879 I 0.360
Nkx6-1 Dipodomys ordii ENSDORG00000004413 I 0.360
NKX6-1 Equus caballus ENSECAG00000021703 I 0.360
ENSFALG00000005328 Ficedula albicollis ENSFALG00000005328 I 0.360
ENSFCAG00000028918 Felis catus ENSFCAG00000028918 I 0.360
NKX6-1 Homo sapiens ENSG00000163623 D 0.360
nkx6.1 Gasterosteus aculeatus ENSGACG00000013430 I 0.360
NKX6-1 Gorilla gorilla ENSGGOG00000008459 I 0.360
ENSGMOG00000012973 Gadus morhua ENSGMOG00000012973 I 0.360
ENSLACG00000010778 Latimeria chalumnae ENSLACG00000010778 I 0.360
ENSLAFG00000030127 Loxodonta africana ENSLAFG00000030127 I 0.360
ENSLOCG00000012142 Lepisosteus oculatus ENSLOCG00000012142 I 0.360
ENSMEUG00000004857 Macropus eugenii ENSMEUG00000004857 I 0.360
NKX6-1 Myotis lucifugus ENSMLUG00000012584 I 0.360
ENSMMUG00000021161 Macaca mulatta ENSMMUG00000021161 I 0.360
NKX6-1 Monodelphis domestica ENSMODG00000020778 I 0.360
ENSMPUG00000010488 Mustela putorius furo ENSMPUG00000010488 I 0.360
Nkx6-1 Mus musculus ENSMUSG00000035187 D 0.360
ENSNLEG00000009157 Nomascus leucogenys ENSNLEG00000009157 I 0.360
NKX6-1 Oryctolagus cuniculus ENSOCUG00000028183 I 0.360
NKX6-1 Otolemur garnettii ENSOGAG00000000028 I 0.360
ENSONIG00000012511 Oreochromis niloticus ENSONIG00000012511 I 0.360
ENSORLG00000019018 Oryzias latipes ENSORLG00000019018 I 0.360
ENSPANG00000025577 Papio anubis ENSPANG00000025577 I 0.360
ENSPPYG00000014901 Pongo abelii ENSPPYG00000014901 I 0.360
ENSPSIG00000015332 Pelodiscus sinensis ENSPSIG00000015332 I 0.360
NKX6-1 Pan troglodytes ENSPTRG00000016239 I 0.360
Nkx6-1 Rattus norvegicus ENSRNOG00000002149 I 0.360
ENSSHAG00000014919 Sarcophilus harrisii ENSSHAG00000014919 I 0.360
ENSSTOG00000012588 Ictidomys tridecemlineatus ENSSTOG00000012588 I 0.360
ENSTGUG00000002130 Taeniopygia guttata ENSTGUG00000002130 I 0.360
nkx6.1 Tetraodon nigroviridis ENSTNIG00000009010 I 0.360
nkx6.1 Takifugu rubripes ENSTRUG00000002910 I 0.360
ENSTRUG00000018647 Takifugu rubripes ENSTRUG00000018647 I 0.360
nkx6.1 Takifugu rubripes ENSTRUG00000018648 I 0.360
ENSTSYG00000009252 Tarsius syrichta ENSTSYG00000009252 I 0.360
NKX6-1 Tursiops truncatus ENSTTRG00000001971 I 0.360
ENSXMAG00000012212 Xiphophorus maculatus ENSXMAG00000012212 I 0.360
Alligator_sinensis_CCG001589.1 Alligator sinensis Alligator_sinensis_CCG001589.1 I 0.360
ENSBTAP00000003266-D2 Bos grunniens ENSBTAP00000003266-D2 I 0.360
ENSMMUP00000027862 Macaca fascicularis ENSMMUP00000027862 I 0.360
Ogr08540 Ophisaurus gracilis Ogr08540 I 0.360
estExt_GenewiseH_1.C_2940047 Branchiostoma floridae estExt_GenewiseH_1.C_2940047 I 0.360
nkx6-1 Xenopus tropicalis XB-GENE-483574 I 0.360
nkx6-1.L Xenopus laevis XB-GENE-864993 I 0.360