lin-28 (Drosophila melanogaster)
CSD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00313 (CSD) IPR002059 FBgn0035626 T164862_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables mRNA 3'-UTR binding activity. Involved in several processes, including germ-line stem-cell niche homeostasis; negative regulation of RNA metabolic process; and positive regulation of signal transduction. Located in cytoplasmic stress granule and cytosol. Is expressed in several structures, including circulatory system; cuboidal/columnar epithelium; embryonic/larval muscle system; extended germ band embryo; and testis. Orthologous to several human genes including LIN28A (lin-28 homolog A). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
lin-28
M03713_2.00		 Drosophila melanogaster
KCGTGTAGGTCGGTGGB
VCCACCGACCTACACGM		 SELEX
Nitta et al.(2015)
lin-28_1		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0076798 CSD 39 104

Links

Other CSD family TFs
Other Drosophila melanogaster TFs

31 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
GA14466 Drosophila pseudoobscura FBgn0074494 I 0.939
MDOA004026 Musca domestica MDOA004026 I 0.879
LCUP008192 Lucilia cuprina LCUP008192 I 0.864
TC014742 Tribolium castaneum TC014742 I 0.803
AMIN007802 Anopheles minimus AMIN007802 I 0.773
LLOJ008847 Lutzomyia longipalpis LLOJ008847 I 0.758
ACUA024423 Anopheles culicifacies ACUA024423 I 0.758
AFUN002605 Anopheles funestus AFUN002605 I 0.758
AFAF013794 Anopheles farauti AFAF013794 I 0.758
ASIS012373 Anopheles sinensis ASIS012373 I 0.758
HMEL007073 Heliconius melpomene HMEL007073 I 0.758
AATE020348 Anopheles atroparvus AATE020348 I 0.742
MCINX009795 Melitaea cinxia MCINX009795 I 0.742
ASTEI02701 Anopheles stephensi ASTEI02701 I 0.742
AALB005062 Anopheles albimanus AALB005062 I 0.742
tetur15g00620 Tetranychus urticae tetur15g00620 I 0.742
RPRC012403 Rhodnius prolixus RPRC012403 I 0.742
BGIBMGA000377 Bombyx mori BGIBMGA000377 I 0.742
KGM_16662 Danaus plexippus KGM_16662 I 0.742
AQUA004698 Anopheles quadriannulatus AQUA004698 I 0.727
AMEC021668 Anopheles melas AMEC021668 I 0.727
AARA008465 Anopheles arabiensis AARA008465 I 0.727
HHAL010561-PA Halyomorpha halys HHAL010561-PA I 0.727
SMAR011791 Strigamia maritima SMAR011791 I 0.727
AEPI008253 Anopheles epiroticus AEPI008253 I 0.727
ACHR009791 Anopheles christyi ACHR009791 I 0.727
ADIR007387 Anopheles dirus ADIR007387 I 0.727
ACOM039486 Anopheles coluzzii ACOM039486 I 0.727
AGAP006591 Anopheles gambiae AGAP006591 I 0.727
CpipJ_CPIJ011213 Culex pipiens CpipJ_CPIJ011213 I 0.712
CPIJ011213 Culex quinquefasciatus CPIJ011213 I 0.712